Top Greater South Side Hotels from ₩85,222

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Our top choices for Greater South Side hotels

A spacious hotel lobby with a central bar, seating area, and a ceiling fan.

1. Hampton Inn Des Moines-Airport

Greater South Side

Tom

₩151,445 total

includes taxes & fees

Nov 27 - Nov 28

A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.

2. Days Inn & Suites by Wyndham Des Moines Airport

Greater South Side

Abdifatah

₩101,812 total

includes taxes & fees

Nov 24 - Nov 25

3. Quality Inn & Suites Des Moines Airport

Greater South Side

Jennifer

₩95,449 total

includes taxes & fees

Dec 6 - Dec 7

A reception desk with a sign reading "AmericInn" and a clock on the wall.

4. AmericInn by Wyndham Des Moines Airport

Greater South Side

Traci

₩95,448 total

includes taxes & fees

Nov 29 - Nov 30

A multi-level indoor atrium with a central pool, surrounded by seating areas and potted plants.

5. Holiday Inn Des Moines-Airport/Conf Center by IHG

Greater South Side

sandeep

₩170,685 total

includes taxes & fees

Dec 13 - Dec 14

A luxurious living room with a stone fireplace, a large mirror, and two blue armchairs.

6. Des Lux Hotel

Court District, 3.9 km from Greater South Side

Bryan

₩241,216 total

includes taxes & fees

Nov 16 - Nov 17

A spacious lobby with high ceilings, large windows, and a chandelier.

7. Hotel Fort Des Moines, Curio Collection by Hilton

Western Gateway, 3.7 km from Greater South Side

Christopher

₩186,616 total

includes taxes & fees

Nov 29 - Nov 30

An indoor swimming pool with clear water, a no diving sign, and a pool ladder.

8. Holiday Inn Express & Suites Des Moines Downtown by IHG

Downtown Des Moines, 3.2 km from Greater South Side

CaSandra

₩200,630 total

includes taxes & fees

Nov 16 - Nov 17

A spacious lobby with a bar area, seating arrangements, and a high ceiling with recessed lighting.

9. Des Moines Marriott Downtown

Downtown Des Moines, 4.1 km from Greater South Side

Benjamin

₩188,651 total

includes taxes & fees

Nov 22 - Nov 23

A modern building with a sign that reads 'Staybridge Suites.' It features a mix of glass and brick facades, large windows, and a flat roof.

10. Staybridge Suites Des Moines Downtown by IHG

Historic East Village, 4.5 km from Greater South Side

Emily

₩145,233 total

includes taxes & fees

Dec 7 - Dec 8

An outdoor seating area with a circular fire pit, wicker furniture, and string lights.

11. Residence Inn Des Moines Downtown

Court District, 3.9 km from Greater South Side

Jill

₩156,792 total

includes taxes & fees

Dec 7 - Dec 8

12. Renaissance Des Moines Savery Hotel

Downtown Des Moines, 4.2 km from Greater South Side

Amy

₩187,305 total

includes taxes & fees

Nov 23 - Nov 24

A modern lobby with a central bar area, seating arrangements, and a distinctive ceiling design.

13. Hilton Des Moines Downtown

Downtown Des Moines, 4.5 km from Greater South Side

Leanna

₩201,065 total

includes taxes & fees

Nov 22 - Nov 23

A modern bar with wooden shelves and a long counter.

14. Surety Hotel, Autograph Collection

Court District, 3.8 km from Greater South Side

Brett

₩227,581 total

includes taxes & fees

Nov 29 - Nov 30

An outdoor dining area with a table set for two, a city skyline in the background, and a Ferris wheel illuminated against the evening sky.

15. Embassy Suites by Hilton Des Moines Downtown

Historic East Village, 4.4 km from Greater South Side

Dennis

₩195,210 total

includes taxes & fees

Nov 22 - Nov 23

A spacious hotel lobby with a blue sofa, a grey armchair, and a flat-screen TV mounted on a textured wall.

16. Comfort Inn & Suites Event Center

Downtown Des Moines, 4.9 km from Greater South Side

Ana

₩138,719 total

includes taxes & fees

Nov 25 - Nov 26

An outdoor patio area with tables and chairs, a fire pit, and string lights.

17. Fairfield Inn & Suites by Marriott Des Moines Downtown

Downtown Des Moines, 4.8 km from Greater South Side

CINDY

₩169,966 total

includes taxes & fees

Nov 23 - Nov 24

An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

18. Home2 Suites by Hilton Des Moines at Drake University

Drake, 5.6 km from Greater South Side

FNU

₩138,719 total

includes taxes & fees

Dec 14 - Dec 15

A modern dining area with a large island table, multiple chairs, and a chandelier.

19. Hampton Inn & Suites Des Moines Downtown

Court District, 3.9 km from Greater South Side

Kristy

₩170,656 total

includes taxes & fees

Nov 22 - Nov 23

A multi-story hotel with a classic brick facade, large windows, and a prominent Liberty Building sign.

20. Hyatt Place Des Moines/Downtown

Downtown Des Moines, 4.1 km from Greater South Side

Valerie

₩164,173 total

includes taxes & fees

Nov 17 - Nov 18

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Compare popular hotels in Greater South Side

Property	Property class	Guest rating
Hampton Inn Des Moines-Airport	2.5 star property	8.8 Excellent 1,002 reviews	View
Days Inn & Suites by Wyndham Des Moines Airport	2.0 star property	8.6 Excellent 1,845 reviews	View
Holiday Inn Des Moines-Airport/Conf Center by IHG	3.0 star property	8.4 Very good 742 reviews	View
AmericInn by Wyndham Des Moines Airport	3.0 star property	8.0 Very good 1,005 reviews	View
Quality Inn & Suites Des Moines Airport	2.5 star property	7.6 Good 1,000 reviews	View

Where to stay in Greater South Side

Find the best Greater South Side areas and neighborhoods for the activities you enjoy most.

The entrance to the Greater Des Moines Botanical Garden with a large dome structure in the background.

Downtown Des Moines

Downtown Des Moines boasts corporate campuses, fine dining, and unique retail destinations. Explore the Pappajohn Sculpture Park, and enjoy easy access to DART transit and skywalk connections.

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Historic East Village

Directly east of Downtown Des Moines, this nationally recognized historic district boasts the Iowa State Capitol complex, State of Iowa Historical Museum, and Des Moines Botanical Gardens. Explore eateries, boutique shops, and loft-style housing in its charming structures.

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A city skyline at night with illuminated buildings and a prominent tower.

Court District

Court District is known for its ample dining options, and you can make a stop by Science Center of Iowa and Principal Park while in the area.

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The exterior and interior of Mars Cafe, featuring a brick facade, large windows, and a red interior with hanging lights and artwork.

Drake

If you're spending some time in Drake, Knapp Center and Des Moines Community Playhouse are top sights worth seeing.

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A city skyline at dusk with illuminated buildings, a bridge, and a river.

Beaverdale

If you're looking for some top things to see and do in Beaverdale and surrounding area, you can visit Merle Hay Mall and Knapp Center.

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Top Greater South Side Hotel Reviews

Hotel Fort Des Moines, Curio Collection by Hilton

Downtown Des Moines

10/10 Excellent

This is one of the nicest hotels I’ve ever stayed at. Absolutely beautiful historic building with a grand scale and fully updated modern rooms. The design and comfort is impeccable. Large room and bathroom, but not so large that it isn’t cozy. Perfect in my opinion. The onsite dining options are fantastic for world class breakfast lunch and dinner at very reasonable prices. And the coffee is amazing. There were a couple of quirks in the room—the sound of trickling water whenever the ac turned...

David Morrow

Home2 Suites by Hilton Des Moines at Drake University

Drake

10/10 Excellent

Cassandra

Surety Hotel, Autograph Collection

Downtown Des Moines

10/10 Excellent

Serenity

A modern hotel lobby with a round coffee table, sofas, and a TV mounted on the wall.

Homewood Suites by Hilton Des Moines Airport

Des Moines

10/10 Excellent

Theodore

A sunroom with a glass ceiling, wicker furniture, and potted plants.

Baymont by Wyndham Des Moines Airport

Southwestern Hills

10/10 Excellent

Andrew

Staybridge Suites Des Moines Downtown by IHG

Downtown Des Moines

10/10 Excellent

Darin

Holiday Inn Express & Suites Des Moines Downtown by IHG

Downtown Des Moines

10/10 Excellent

Anonymous traveler

A hotel with a reflection in a calm body of water, surrounded by open fields.

Fairfield Inn & Suites Des Moines Altoona

Altoona

10/10 Excellent

We love this hotel! We've stayed 2-3 times in the last couple of years. This last time was the best, starting with Michelle, who checked us into the hotel. She was so friendly, knowledgeable, and just great in representing the hotel. Our room was fantastic, beds were so comfortable even after a full day at Adventureland. The shower had multiple adjustments, and it had these awesome shampoo, conditioner, and body wash pumps on the wall of the shower - they smelled wonderful! The pool/whirlpool...

Anonymous traveler

A spacious indoor area with a long wooden table, several chairs, a fireplace, and a view through large windows.

La Quinta Inn & Suites by Wyndham Johnston

Johnston

10/10 Excellent

Erica

Frequently Asked Questions

What's it like in Greater South Side?

Travelers are sure to enjoy a stay in Des Moines's Greater South Side neighborhood. Consider a visit to Gray’s Lake Park as part of your Greater South Side travel plans.

What's a favorite place to stay in Greater South Side?

Based on our traveler data, Days Inn & Suites by Wyndham Des Moines Airport is one of the top choices for your stay in Greater South Side. This hotel offers free breakfast and an indoor pool. Other good options for your stay in the neighborhood include Hampton Inn Des Moines-Airport and AmericInn by Wyndham Des Moines Airport.

How many hotels will I be able to find in Greater South Side?

With 17 Expedia hotels and other accommodations in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.

If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals in Greater South Side.

Where can I learn more about changing or cancelling my trip to Greater South Side?

For more information about changing or cancelling your trip to Greater South Side, head over to our customer service page.

What is there to do around this Des Moines neighborhood?

Gray’s Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.

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Find hotels in Greater South Side, Des Moines from ₩85,222

Change your mind

Treat yourself

Be picky

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Property class

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Our top choices for Greater South Side hotels

1. Hampton Inn Des Moines-Airport

2. Days Inn & Suites by Wyndham Des Moines Airport

3. Quality Inn & Suites Des Moines Airport

4. AmericInn by Wyndham Des Moines Airport

5. Holiday Inn Des Moines-Airport/Conf Center by IHG

6. Des Lux Hotel

7. Hotel Fort Des Moines, Curio Collection by Hilton

8. Holiday Inn Express & Suites Des Moines Downtown by IHG

9. Des Moines Marriott Downtown

10. Staybridge Suites Des Moines Downtown by IHG

11. Residence Inn Des Moines Downtown

12. Renaissance Des Moines Savery Hotel

13. Hilton Des Moines Downtown

14. Surety Hotel, Autograph Collection

15. Embassy Suites by Hilton Des Moines Downtown

16. Comfort Inn & Suites Event Center

17. Fairfield Inn & Suites by Marriott Des Moines Downtown

18. Home2 Suites by Hilton Des Moines at Drake University

19. Hampton Inn & Suites Des Moines Downtown

20. Hyatt Place Des Moines/Downtown

Compare popular hotels in Greater South Side

Where to stay in Greater South Side

Downtown Des Moines

Historic East Village

Court District

Drake

Beaverdale

Top Greater South Side Hotel Reviews

Hotel Fort Des Moines, Curio Collection by Hilton

10/10 Excellent

Frequently Asked Questions

What's it like in Greater South Side?

What's a favorite place to stay in Greater South Side?

How many hotels will I be able to find in Greater South Side?

If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?

Where can I learn more about changing or cancelling my trip to Greater South Side?

What is there to do around this Des Moines neighborhood?

Explore a world of travel with Expedia