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Sep 11 - Sep 13
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Our top choices for Greater South Side hotels

A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.

1. Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1,833 reviews)
"Great location nice staff"
United States
John
The price is ₩94,768
₩106,141 total
includes taxes & fees
Sep 20 - Sep 21
Days Inn & Suites by Wyndham Des Moines Airport
A spacious hotel lobby with a central bar, seating area, and a ceiling fan.

2. Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Greater South Side
8.8 out of 10, Excellent, (1,005 reviews)
"Everything was pleasant enjoyed our stay!"
United States
Crystal
The price is ₩153,433
₩171,845 total
includes taxes & fees
Sep 13 - Sep 14
Hampton Inn Des Moines-Airport
A reception desk with a sign reading "AmericInn" and a clock on the wall.

3. AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport
3.0 star property
Greater South Side
8.0 out of 10, Very Good, (1,010 reviews)
"Great place"
United States
Milagros
The price is ₩86,961
₩97,397 total
includes taxes & fees
Sep 10 - Sep 11
AmericInn by Wyndham Des Moines Airport

4. Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport
2.5 star property
Greater South Side
7.6 out of 10, Good, (1,004 reviews)
"Very convenient, next to airport and free shuttle."
United States
JAVIER
The price is ₩85,816
₩96,114 total
includes taxes & fees
Sep 28 - Sep 29
Quality Inn & Suites Des Moines Airport
A spacious indoor area with multiple levels, featuring a central open space with tables and chairs, surrounded by balconies and a large, colorful ceiling structure.

5. Holiday Inn Des Moines-Airport/Conf Center by IHG

Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
Greater South Side
8.4 out of 10, Very Good, (714 reviews)
"Great place to stay"
United States
Reginald
The price is ₩141,345
₩158,306 total
includes taxes & fees
Sep 13 - Sep 14
Holiday Inn Des Moines-Airport/Conf Center by IHG
A spacious lobby with high ceilings, large windows, and a chandelier.

6. Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton
4.5 star property
Western Gateway, 3.7 km from Greater South Side
9.6 out of 10, Exceptional, (1,295 reviews)
"Very nice and clean I enjoyed my stay"
United States
LaSeana
The price is ₩175,510
₩196,572 total
includes taxes & fees
Sep 7 - Sep 8
Hotel Fort Des Moines, Curio Collection by Hilton
A Holiday Inn Express building with a brick facade, multiple windows, and a covered entrance.

7. Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG
2.5 star property
Downtown Des Moines, 3.2 km from Greater South Side
9.2 out of 10, Wonderful, (1,002 reviews)
"Would stay there again."
United States
Meg
The price is ₩133,268
₩149,261 total
includes taxes & fees
Oct 4 - Oct 5
Holiday Inn Express & Suites Des Moines Downtown by IHG
A luxurious living room with a stone fireplace, a large mirror, and two blue armchairs.

8. Des Lux Hotel

Des Lux Hotel
3.5 star property
Court District, 3.9 km from Greater South Side
9.6 out of 10, Exceptional, (1,089 reviews)
"I love staying here for the ambience and hot breakfast."
United States
Angela
The price is ₩204,748
₩229,329 total
includes taxes & fees
Sep 7 - Sep 8
Des Lux Hotel
An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

9. Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University
3.0 star property
Drake, 5.6 km from Greater South Side
9.4 out of 10, Exceptional, (1,013 reviews)
"Will stay there again!!!"
United States
Ashley
The price is ₩142,395
₩159,482 total
includes taxes & fees
Sep 20 - Sep 21
Home2 Suites by Hilton Des Moines at Drake University
A modern kitchen with dark cabinets, stainless steel appliances, and a tiled backsplash.

10. Staybridge Suites Des Moines Downtown by IHG

Staybridge Suites Des Moines Downtown by IHG
3.0 star property
Historic East Village, 4.5 km from Greater South Side
9.2 out of 10, Wonderful, (1,000 reviews)
"Terrific location, great happy hour, nice staff. Would definitely stay here again"
United States
Dawn R.
The price is ₩173,652
₩194,490 total
includes taxes & fees
Sep 7 - Sep 8
Staybridge Suites Des Moines Downtown by IHG
An outdoor dining area with a table set for two, featuring a cocktail and candles.

11. Embassy Suites Hotel Des Moines Downtown

Embassy Suites Hotel Des Moines Downtown
3.5 star property
Historic East Village, 4.4 km from Greater South Side
8.4 out of 10, Very Good, (1,005 reviews)
"Such a wonderful hotel and amazing staff and fantastic rooms!"
United States
Candy
The price is ₩175,510
₩196,571 total
includes taxes & fees
Sep 20 - Sep 21
Embassy Suites Hotel Des Moines Downtown
A spacious lobby with a bar area, seating arrangements, and a high ceiling with recessed lighting.

12. Des Moines Marriott Downtown

Des Moines Marriott Downtown
3.5 star property
Downtown Des Moines, 4.1 km from Greater South Side
8.8 out of 10, Excellent, (1,001 reviews)
"Beautiful place easy to navigate and staff was super kind"
United States
clayton
The price is ₩193,844
₩217,106 total
includes taxes & fees
Sep 20 - Sep 21
Des Moines Marriott Downtown
A modern dining area with a large island table, multiple chairs, and a chandelier.

13. Hampton Inn & Suites Des Moines Downtown

Hampton Inn & Suites Des Moines Downtown
2.5 star property
Court District, 3.9 km from Greater South Side
8.6 out of 10, Excellent, (1,004 reviews)
"Incredibly clean stay! Lovely staff."
United States
Lauren
The price is ₩142,395
₩159,482 total
includes taxes & fees
Sep 20 - Sep 21
Hampton Inn & Suites Des Moines Downtown
An outdoor seating area with a circular fire pit, wicker furniture, and string lights.

14. Residence Inn Des Moines Downtown

Residence Inn Des Moines Downtown
3.0 star property
Court District, 3.9 km from Greater South Side
8.8 out of 10, Excellent, (682 reviews)
"This is a clean, pleasant, and familiar place to stay with a great location near the ballpark and Court Avenue district."
United States
Michael
The price is ₩176,519
₩197,701 total
includes taxes & fees
Sep 20 - Sep 21
Residence Inn Des Moines Downtown
A modern hotel lobby with a round coffee table, sofas, and a TV mounted on the wall.

15. Homewood Suites by Hilton Des Moines Airport

Homewood Suites by Hilton Des Moines Airport
3.0 star property
3.7 km from Greater South Side
9.4 out of 10, Exceptional, (678 reviews)
"Nice location"
United States
Galen
The price is ₩160,056
₩179,263 total
includes taxes & fees
Sep 13 - Sep 14
Homewood Suites by Hilton Des Moines Airport
A hotel dining area with multiple tables and chairs, a central fireplace, and potted plants.

16. Fairfield Inn & Suites by Marriott Des Moines Airport

Fairfield Inn & Suites by Marriott Des Moines Airport
3.0 star property
3.3 km from Greater South Side
9.2 out of 10, Wonderful, (676 reviews)
"Great clean hotel close to the airport and restaurants!"
United States
Richard
The price is ₩164,969
₩184,766 total
includes taxes & fees
Sep 20 - Sep 21
Fairfield Inn & Suites by Marriott Des Moines Airport
A multi-story hotel with a classic brick facade, large windows, and a prominent Liberty Building sign.

17. Hyatt Place Des Moines/Downtown

Hyatt Place Des Moines/Downtown
3.0 star property
Downtown Des Moines, 4.1 km from Greater South Side
8.2 out of 10, Very Good, (1,010 reviews)
"staff was extremely helpful"
United States
RYAN
The price is ₩150,768
₩168,860 total
includes taxes & fees
Sep 20 - Sep 21
Hyatt Place Des Moines/Downtown
A sunroom with a glass ceiling, wicker furniture, and potted plants.

18. Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport
2.5 star property
Southwestern Hills, 6.2 km from Greater South Side
9.4 out of 10, Exceptional, (1,205 reviews)
"best hotel I've ever had stayed at"
United States
Paul
The price is ₩129,297
₩144,813 total
includes taxes & fees
Sep 22 - Sep 23
Baymont by Wyndham Des Moines Airport
An indoor swimming pool with a waterfall feature, surrounded by Adirondack chairs and a wooden deck.

19. Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston
2.5 star property
14.3 km from Greater South Side
8.8 out of 10, Excellent, (1,888 reviews)
"Breakfast was great selection of food, good coffee."
United States
Susan
The price is ₩131,499
₩147,279 total
includes taxes & fees
Sep 7 - Sep 8
Stoney Creek Hotel Des Moines - Johnston
A spacious hotel lobby with a blue sofa, a grey armchair, and a flat-screen TV mounted on a textured wall.

20. Comfort Inn & Suites Event Center

Comfort Inn & Suites Event Center
2.5 star property
Downtown Des Moines, 4.9 km from Greater South Side
8.8 out of 10, Excellent, (1,011 reviews)
"Excellent accommodations."
United States
Mark
The price is ₩136,902
₩153,332 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites Event Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Greater South Side

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A spacious hotel lobby with a central bar, seating area, and a ceiling fan.
Hampton Inn Des Moines-Airport
2.5 star property
8.8
Excellent
1,005 reviews
View
A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.
Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
8.6
Excellent
1,833 reviews
View
A spacious indoor area with multiple levels, featuring a central open space with tables and chairs, surrounded by balconies and a large, colorful ceiling structure.
Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
8.4
Very Good
714 reviews
View
A reception desk with a sign reading "AmericInn" and a clock on the wall.
AmericInn by Wyndham Des Moines Airport
3.0 star property
8.0
Very Good
1,010 reviews
View
Quality Inn & Suites Des Moines Airport
2.5 star property
7.6
Good
1,004 reviews
View

Where to stay in Greater South Side

Find the best Greater South Side areas and neighborhoods for the activities you enjoy most.
The entrance to the Greater Des Moines Botanical Garden with a large dome structure in the background.

Downtown Des Moines

Downtown Des Moines boasts corporate campuses, fine dining, and unique retail destinations. Explore the Pappajohn Sculpture Park, and enjoy easy access to DART transit and skywalk connections.

A city skyline at night with illuminated buildings and a prominent tower.
Photo by Ryan Brohm
Open Photo by Ryan Brohm

Court District

Court District is known for its ample dining options, and you can make a stop by Science Center of Iowa and Principal Park while in the area.

A sign reading "Historic East Village" with a clear blue sky and clouds in the background.

Historic East Village

Directly east of Downtown Des Moines, this nationally recognized historic district boasts the Iowa State Capitol complex, State of Iowa Historical Museum, and Des Moines Botanical Gardens. Explore eateries, boutique shops, and loft-style housing in its charming structures.

The exterior and interior of Mars Cafe, featuring a brick facade, large windows, and a red interior with hanging lights and artwork.
Photo by Eric Mondres
Open Photo by Eric Mondres

Drake

If you're spending some time in Drake, Knapp Center and Des Moines Community Playhouse are top sights worth seeing.

A paved road flanked by trees and bushes, leading into the distance.
Photo by Emily Ruschill
Open Photo by Emily Ruschill

Southwestern Hills

While Southwestern Hills might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Gray’s Lake Park and Lauridsen Amphitheater.

Top Greater South Side Hotel Reviews

Sonesta Essential Des Moines

Sonesta Essential Des Moines

10/10 Excellent
"Very clean and perhaps priced below what it should be"
George 1-night trip
Posted 8 hours ago
Sonesta Essential Des Moines

Frequently asked questions

What's it like in Greater South Side?
Travelers are sure to enjoy a stay in Des Moines's Greater South Side neighborhood. Consider a visit to Gray's Lake Park as part of your Greater South Side travel plans.
What's a favorite place to stay in Greater South Side?
Based on our traveler data, Days Inn & Suites by Wyndham Des Moines Airport is one of the top choices for your stay in Greater South Side. This hotel offers free breakfast and an indoor pool. Other good options for your stay in the neighborhood include AmericInn by Wyndham Des Moines Airport and Holiday Inn Des Moines-Airport/Conf Center by IHG.
How many hotels will I be able to find in Greater South Side?
With 19 Expedia hotels and other accommodations in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.
If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals in Greater South Side.
Where can I learn more about changing or cancelling my trip to Greater South Side?
For more information about changing or cancelling your trip to Greater South Side, head over to our customer service page.
What is there to do around this Des Moines neighborhood?
Gray's Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.