Photo by Greater Houston Convention and Visitors Bureau (photographer: Hugh Hargrave)

Find hotels in South Central Houston, Houston from ₩92,009

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Discover 1,142 South Central Houston hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Romantic Room, 1 King Bed | Laptop workspace, blackout drapes, soundproofing, iron/ironing board
Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

2.0 star property
South Central Houston
8.0 out of 10, Very Good, (19)
"Its ok"
United States
Armynd
The price is ₩138,349
₩161,868 total
includes taxes & fees
Nov 12 - Nov 13
Downtowner Inns - Houston Downtown
Sundeck
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 star property
South Central Houston
8.4 out of 10, Very Good, (1662)
"This property is centrally located and amazing to stay at. We had to visit for Medical Reasons so it is walking distance to Methodist Medical Center and also Texas Children’s Hospital. The staff was amazing and very welcoming. The room was very clean and comfortable. "
United States
Jose
The price is ₩128,737
₩152,312 total
includes taxes & fees
Nov 30 - Dec 1
Hilton Houston Plaza/Medical Center
Reception
InterContinental Houston by IHG

InterContinental Houston by IHG

4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1003)
"Very well maintenance property, beautiful lobby and friendly staff."
United States
Viji
The price is ₩202,426
₩265,964 total
includes taxes & fees
Nov 28 - Nov 29
InterContinental Houston by IHG
1 bedroom, premium bedding, pillowtop beds, minibar
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (1815)
"The room was spotless, service was amazing, the food was delicious!"
United States
Jeffrey
The price is ₩290,674
₩399,708 total
includes taxes & fees
Nov 16 - Nov 17
Hotel Zaza Houston Museum District
Daily buffet breakfast for a fee
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
South Central Houston
8.2 out of 10, Very Good, (445)
"Very clean, walking distance to MD Anderson buildings "
United States
William
The price is ₩156,115
₩182,654 total
includes taxes & fees
Nov 27 - Nov 28
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Desk, free WiFi, bed sheets, alarm clocks
Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown

2.0 star property
South Central Houston
8.0 out of 10, Very Good, (1003)
"Nice hotel"
United States
Robert Jeanmard
The price is ₩102,742
₩120,208 total
includes taxes & fees
Nov 12 - Nov 13
Americas Best Value Inn Medical Center Downtown
Outdoor pool, free cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1007)
"Loved staying at this property "
United States
Shetasha
The price is ₩199,419
₩248,217 total
includes taxes & fees
Nov 29 - Nov 30
The Westin Houston Medical Center/Museum District
Lobby
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1004)
"Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy."
United States
Elena
The price is ₩208,397
₩290,208 total
includes taxes & fees
Nov 29 - Nov 30
Houston Marriott Medical Center/Museum District
Lobby
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
South Central Houston
5.8 out of 10, (1005)
"It was ok."
United States
Luis
The price is ₩112,703
₩132,276 total
includes taxes & fees
Nov 16 - Nov 17
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Interior
Wanderstay Houston Hostel

Wanderstay Houston Hostel

2.0 star property
South Central Houston
8.4 out of 10, Very Good, (188)
"EXCELLENT AND CLEAN!"
United States
cory
The price is ₩87,378
₩102,232 total
includes taxes & fees
Nov 13 - Nov 14
Wanderstay Houston Hostel
Exterior
La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B

3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (531)
"Breakfast delicious Customer service excellent"
United States
Emily
The price is ₩260,678
₩304,993 total
includes taxes & fees
Nov 12 - Nov 13
La Maison in Midtown an urban B&B
Outdoor pool
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (197)
"Had the most absolutely amazing time. This will be where we stay every single time we go to Houston. It was so quiet and everything is so luxurious. 10/10 no notes! "
United States
Denisha
The price is ₩276,056
₩344,823 total
includes taxes & fees
Nov 12 - Nov 13
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
1 bedroom, premium bedding, down comforters, pillowtop beds
Hilton University of Houston

Hilton University of Houston

3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (882)
"Great location, great room, no issues at all and would stay again. "
United States
Joe
The price is ₩225,697
₩264,066 total
includes taxes & fees
Nov 18 - Nov 19
Hilton University of Houston
Double Room, 1 Queen Bed with Sofa bed | In-room safe, individually decorated, individually furnished, desk
Wanderstay Boutique Hotel

Wanderstay Boutique Hotel

2.0 star property
South Central Houston
9.8 out of 10, Exceptional, (54)
"Great location will stay again "
United States
Jason
The price is ₩188,736
₩220,823 total
includes taxes & fees
Nov 12 - Nov 13
Wanderstay Boutique Hotel
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout drapes, free WiFi
Southmore Boulevard Motel

Southmore Boulevard Motel

2.0 star property
South Central Houston
5.4 out of 10, (223)
"Good area"
United States
Elba
The price is ₩78,640
₩92,009 total
includes taxes & fees
Nov 18 - Nov 19
Southmore Boulevard Motel
House | 3 bedrooms, Internet
Newly Built Modern 3 Bedroom Houston Home

Newly Built Modern 3 Bedroom Houston Home

2.0 star property
South Central Houston
10.0 out of 10, Exceptional, (2)
"The pictures do not do this property justice. The three story home has 3 beautiful bedrooms, each with luxurious bathrooms. The main bedroom and the living room has a small patio and then there's a rooftop seating area that is an excellent spot for gazing at the Houston night skyline. The quiet area is gated off a not too busy street in a beautiful neighborhood. We did have a couple of issues upon our arrival but the hosts were on top of it and had it resolved the next day. They have great...
United States
robin
The price is ₩214,761
₩582,502 total
includes taxes & fees
Dec 7 - Dec 8
Newly Built Modern 3 Bedroom Houston Home
Fridge, microwave, stovetop, coffee/tea maker
Rodeway Inn & Suites Houston near Medical Center

Rodeway Inn & Suites Houston near Medical Center

2.0 star property
South Central Houston
6.0 out of 10, (498)
"Very economical. Great price for one night stay."
United States
AUGUSTIN
The price is ₩81,262
₩95,076 total
includes taxes & fees
Nov 12 - Nov 13
Rodeway Inn & Suites Houston near Medical Center
House | 3 bedrooms, Internet
Spacious Houston 3bed3 Bath Family Townhome

Spacious Houston 3bed3 Bath Family Townhome

2.0 star property
South Central Houston
6.8 out of 10, (3)
"This rental was beautiful very clean and spacious. The location is very convenient if you are visiting the downtown area and for local shopping. The host was prompt with communicating when needed. It is a three story rental so the only issue was how tiring the stairs could be since the elevator was not available to use. I would definitely recommend and book with this host and rental property again. "
United States
Candance
The price is ₩173,773
₩534,547 total
includes taxes & fees
Nov 25 - Nov 26
Spacious Houston 3bed3 Bath Family Townhome
Comfort Townhome | Private kitchen | Full-size fridge, microwave, oven, dishwasher
Modern Cozy Home with King Bed

Modern Cozy Home with King Bed

3.5 star property
South Central Houston
9.4 out of 10, Exceptional, (21)
"Very spacious and close to just about everything. The view is amazing too"
United States
Brenden
The price is ₩196,600
₩506,719 total
includes taxes & fees
Nov 30 - Dec 1
Modern Cozy Home with King Bed
House | 4 bedrooms, desk, iron/ironing board, Internet
Paradise Palace Best Rooftop in HTX w Hot Tub

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
South Central Houston
The price is ₩450,831
₩1,024,321 total
includes taxes & fees
Nov 12 - Nov 13
Paradise Palace Best Rooftop in HTX w Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Northside

While you're in Northside, take in top sights like The Heights Theater or Greenspoint Mall, and hop on the metro to see more the city at Northline Transit Center/HCC Station or Melbourne/North Lindale Station.

Top South Central Houston Hotel Reviews

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

10/10 Excellent
"All was good. The parking was not free. $20 to park."
Judy 1-night trip
Posted 1 day ago
Hilton Houston Plaza/Medical Center

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Frequently asked questions

What's it like in South Central Houston?
Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighborhood.
What's the best accommodation in South Central Houston?
Based on Expedia customer reviews, La Maison in Midtown an urban B&B is the highest ranked property in South Central Houston. This B&B is a short 4-minute walk from Westheimer Road, and it offers free breakfast and free parking. Other favorite options in the area include Wanderstay Boutique Hotel and MyCrib Houston Hostel.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1145 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.
Where can I learn more about changing or cancelling my trip to South Central Houston?
To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.
What is there to do around this Houston neighborhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Bagby Dog Park. Houston Zoo and Continental Club are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station.