Find hotels in South Central Houston, Houston from ₩87,581

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Discover 1,155 South Central Houston hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hilton Houston Plaza/Medical Center
Sundeck

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very Good, (1611)
"Very nice staff, enjoyed our stay"
The price is ₩125,549
₩148,528 total
includes taxes & fees
Oct 12 - Oct 13
Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG
Reception

InterContinental Houston by IHG

4.0 star property
9.4 out of 10, Exceptional, (1019)
"Awesome location. "
The price is ₩218,477
₩283,811 total
includes taxes & fees
Oct 5 - Oct 6
InterContinental Houston by IHG
Hotel Zaza Houston Museum District
1 bedroom, premium bedding, pillowtop beds, minibar

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1784)
"Great stay at Hotel Zaza. The staff is amazing, accommodating, friendly, helpful!"
The price is ₩381,862
₩507,439 total
includes taxes & fees
Oct 2 - Oct 3
Hotel Zaza Houston Museum District
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Daily buffet breakfast for a fee

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.2 out of 10, Very Good, (427)
"Great stay, shuttle to MD Anderson very convenient, they let us check out 1 hour later to accommodate Dr appt. "
The price is ₩192,764
₩225,534 total
includes taxes & fees
Oct 5 - Oct 6
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Americas Best Value Inn Medical Center Downtown
Desk, free WiFi, bed sheets, alarm clocks

Americas Best Value Inn Medical Center Downtown

2.0 star property
8.0 out of 10, Very Good, (1010)
"Clean and convenient to the medical center."
The price is ₩105,305
₩123,208 total
includes taxes & fees
Sep 30 - Oct 1
Americas Best Value Inn Medical Center Downtown
The Westin Houston Medical Center/Museum District
Outdoor pool, free cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1025)
"Great place to stay. "
The price is ₩239,792
₩298,467 total
includes taxes & fees
Oct 5 - Oct 6
The Westin Houston Medical Center/Museum District
Houston Marriott Medical Center/Museum District
Lobby lounge

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1010)
"Enjoyed the stay"
The price is ₩265,166
₩315,073 total
includes taxes & fees
Oct 11 - Oct 12
Houston Marriott Medical Center/Museum District
Wanderstay Houston Hostel
Interior

Wanderstay Houston Hostel

2.0 star property
8.4 out of 10, Very Good, (184)
"This is an amazing place to stay."
The price is ₩84,583
₩98,962 total
includes taxes & fees
Sep 30 - Oct 1
Wanderstay Houston Hostel
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1015)
"the place if very clean, beds are comfortable, A/C works great and quiet and the staff (Maria, Sasha) were great people. I would definitely recommend staying here again. "
The price is ₩111,635
₩131,033 total
includes taxes & fees
Sep 30 - Oct 1
Extended Stay America Suites Houston Med Ctr Braeswood Bl
La Maison in Midtown an urban B&B
Exterior

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (520)
"Nice property we are enjoying our stay. "
The price is ₩252,338
₩295,235 total
includes taxes & fees
Oct 5 - Oct 6
La Maison in Midtown an urban B&B
Downtowner Inns - Houston Downtown
Exterior

Downtowner Inns - Houston Downtown

2.0 star property
7.0 out of 10, Good, (4)
"Clean room"
The price is ₩133,922
₩156,689 total
includes taxes & fees
Sep 30 - Oct 1
Downtowner Inns - Houston Downtown
Wanderstay Boutique Hotel
Double Room, 1 Queen Bed with Sofa bed | In-room safe, individually decorated, individually furnished, desk

Wanderstay Boutique Hotel

2.0 star property
9.8 out of 10, Exceptional, (47)
"The staff was amazing!! The hotel is beautiful and very clean!!"
The price is ₩182,698
₩213,758 total
includes taxes & fees
Sep 30 - Oct 1
Wanderstay Boutique Hotel
Hilton University of Houston
1 bedroom, premium bedding, down comforters, pillowtop beds

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (864)
"Overall decent property "
The price is ₩225,272
₩263,569 total
includes taxes & fees
Oct 24 - Oct 25
Hilton University of Houston
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (191)
"This was a wonderful place to stay!!"
The price is ₩244,359
₩307,049 total
includes taxes & fees
Sep 30 - Oct 1
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Southmore Boulevard Motel
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout drapes, free WiFi

Southmore Boulevard Motel

2.0 star property
5.4 out of 10, (220)
"A classical Motel like in a Movie. The staff was really kind and helpful."
The price is ₩78,930
₩92,350 total
includes taxes & fees
Sep 30 - Oct 1
Southmore Boulevard Motel
Rodeway Inn & Suites Houston near Medical Center
Fridge, microwave, stovetop, coffee/tea maker

Rodeway Inn & Suites Houston near Medical Center

2.0 star property
6.2 out of 10, (491)
"Staff are rude"
The price is ₩74,856
₩87,581 total
includes taxes & fees
Sep 30 - Oct 1
Rodeway Inn & Suites Houston near Medical Center
Modern Cozy Home with King Bed
Comfort Townhome | Private kitchen | Full-size fridge, microwave, oven, dishwasher

Modern Cozy Home with King Bed

3.5 star property
9.4 out of 10, Exceptional, (20)
"Very spacious and close to just about everything. The view is amazing too"
The price is ₩190,311
₩490,509 total
includes taxes & fees
Sep 30 - Oct 1
Modern Cozy Home with King Bed
Posh Dtwn Midtown Home w Stunning Roof-topterrace
House | 4 bedrooms, soundproofing, bed sheets

Posh Dtwn Midtown Home w Stunning Roof-topterrace

3.0 star property
Posh Dtwn Midtown Home w Stunning Roof-topterrace
The Green Haus Luxxe Cabana Rooftop Retreat
Apartment | 4 bedrooms, desk, Internet

The Green Haus Luxxe Cabana Rooftop Retreat

2.0 star property
10.0 out of 10, Exceptional, (1)
The price is ₩372,771
₩917,093 total
includes taxes & fees
Oct 1 - Oct 2
The Green Haus Luxxe Cabana Rooftop Retreat
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
House, 3 Bedrooms | Private kitchen | Fridge, oven, coffee/tea maker, electric kettle

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

3.0 star property
The price is ₩300,733
₩840,948 total
includes taxes & fees
Oct 1 - Oct 2
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Houston featuring a city and a high rise building

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Top South Central Houston Hotel Reviews

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown

10/10 Excellent
"Staff were very accommodating. Room was clean and bed comfortable. Only complaint was the sheets are cheap and itchy. We will definitely stay again when we have to stay over night in Houston. It’s close to the medical district "
Kimberly 1-night trip
Posted 3 days ago
Americas Best Value Inn Medical Center Downtown

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in South Central Houston?

Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighborhood.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, Wanderstay Boutique Hotel is the highest ranked property in South Central Houston. This hotel offers free parking and free WiFi. Other favorite options in the area include La Maison in Midtown an urban B&B and The Westin Houston Medical Center/Museum District.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1153 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.

Where can I learn more about changing or cancelling my trip to South Central Houston?

To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.

What is there to do around this Houston neighborhood?

Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Bagby Dog Park. Houston Zoo and Continental Club are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station.