The Best Hotels Closest to Lewis and Clark Trail Trailhead in St. Louis for 2026

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Our top choices for Lewis and Clark Trail Trailhead hotels

A hotel room with a bed, a sofa, a coffee table, and wall art.

A restaurant with wooden tables and chairs, a blue wall with white floral patterns, and a counter with a coffee machine.

A Sleep Inn & Suites hotel with a modern brick facade, a covered entrance, and a parking lot.

A hotel lobby with a reception desk, seating area, and a large potted plant.

1. Sleep Inn & Suites O'Fallon MO - Technology Drive

3.2 km from Lewis and Clark Trail Trailhead

Matthew

₩109,391

₩129,026 total

includes taxes & fees

Nov 10 - Nov 11

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

A reception desk with a modern design, featuring a blue geometric wall and a wooden finish.

A Holiday Inn Express hotel with a brick facade, a covered entrance, and a clear sky.

A breakfast bar with a digital menu board, fruit bowls, cereal dispensers, and condiments.

2. Holiday Inn Express St. Louis West - O'Fallon by IHG

3.2 km from Lewis and Clark Trail Trailhead

Greg

₩123,788

₩146,008 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a central round table, two sofas, and a chandelier.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

A buffet setup with various food items and a decorative vase of flowers.

3. Drury Plaza Hotel St. Louis Chesterfield

14.8 km from Lewis and Clark Trail Trailhead

Chasity

₩172,464

₩200,038 total

includes taxes & fees

Oct 25 - Oct 26

A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

A modern bathroom with a large mirror, white vanity, and a bathtub.

A formal dining table set for six with a vase of white flowers, candles, and a view of buildings through large windows.

A hotel room with a large bed, a bedside lamp, a telephone, a mirror, and a bathroom with a sink and towel rack.

4. The Wildwood Hotel

14.7 km from Lewis and Clark Trail Trailhead

Lori

₩110,086

₩128,237 total

includes taxes & fees

Oct 26 - Oct 27

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

5. Hyatt Place St. Louis/Chesterfield

14.9 km from Lewis and Clark Trail Trailhead

Debbie

₩160,007

₩185,589 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a high ceiling, a dining area, and a seating area with sofas and a coffee table.

An indoor swimming pool with clear blue water, a tiled floor, and a ceiling with square vents.

An outdoor patio area with a table and chairs, a glass door entrance, and a visible interior with a dining area.

A hotel room with a bed, a dresser, a nightstand with a lamp, a framed map on the wall, and a carpeted floor.

6. Drury Inn & Suites St. Louis St. Peters

15 km from Lewis and Clark Trail Trailhead

Ashley

₩146,402

₩168,289 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio with a built-in grill, seating area, and stone walls.

A spacious lounge area with a stone fireplace, comfortable seating, and a large TV screen.

An indoor swimming pool with clear glass walls, sunlit seating area, and lifeguard station.

A modern lobby with a stone accent wall, a flat-screen TV, a reception desk, seating area with sofas and ottomans, and a patterned rug.

7. Residence Inn by Marriott St. Louis Chesterfield

12.4 km from Lewis and Clark Trail Trailhead

Chelsea

₩251,568

₩294,304 total

includes taxes & fees

Oct 27 - Oct 28

An outdoor seating area with a table and chairs, a fire feature, and a brick wall.

A hotel lobby with a seating area, tables, and a TV screen.

A bar area with a counter, stools, and shelves with bottles and glasses.

A hotel room with a bed, bedside tables, a wardrobe, and a window with curtains.

8. SpringHill Suites by Marriott St. Louis Chesterfield

15.6 km from Lewis and Clark Trail Trailhead

Jamie

₩162,288

₩188,234 total

includes taxes & fees

Nov 19 - Nov 20

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A hotel room with two beds, a desk, a blue sofa, and a TV.

A modern lobby with a reception desk, seating area, and a dining section.

9. Holiday Inn Express & Suites St Peters by IHG

13.4 km from Lewis and Clark Trail Trailhead

Serah

₩157,064

₩188,770 total

includes taxes & fees

Oct 25 - Oct 26

A hotel reception area with a counter, coffee machines, a refrigerated display, and artwork on the wall.

A reception desk with a wooden finish, a clock, and a sign for Marriott Bonvoy.

An indoor swimming pool with clear water, a diving board, and a seating area with tables and chairs.

A snack bar with shelves of chips, candies, and bottled water.

10. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

15.6 km from Lewis and Clark Trail Trailhead

Charles

₩142,555

₩165,347 total

includes taxes & fees

Oct 30 - Oct 31

An indoor swimming pool with clear water, a tiled border, and a no diving sign.

A Hampton Inn by Hilton sign in front of a building with a brick facade and multiple windows.

An indoor swimming pool with a clear water edge, a pool ladder, and a tiled floor.

A Hampton Inn building with a beige facade, American flag, and a sign above the entrance.

11. Hampton Inn St. Louis/Chesterfield

14.8 km from Lewis and Clark Trail Trailhead

joe

₩139,839

₩162,197 total

includes taxes & fees

Nov 2 - Nov 3

An outdoor patio area with wicker furniture, a stone fire pit, and a building in the background.

A modern bar area with wooden furniture, a counter with a menu, and a seating area with tables and chairs.

A modern lobby with a sofa, armchairs, a coffee table, and a bookshelf.

12. Courtyard by Marriott St. Louis St. Peters

17.3 km from Lewis and Clark Trail Trailhead

Krystle

₩160,525

₩192,783 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.

A large, multi-story hotel with the name "Doubletree by Hilton" prominently displayed on the facade.

A hotel room with a large bed, a desk with a chair, a television, a mirror, and a wardrobe.

A hotel room with orange furniture, a glass coffee table, a dining area with a table and chairs, and a patterned carpet.

13. DoubleTree by Hilton Hotel St. Louis - Chesterfield

13.9 km from Lewis and Clark Trail Trailhead

April

₩184,457

₩213,948 total

includes taxes & fees

Oct 30 - Oct 31

A modern hotel with a prominent entrance, a landscaped courtyard, and a well-lit facade.

A modern conference room with a large table, four chairs, a computer, and a bookshelf with books and a framed picture.

An outdoor patio area with a stone wall, seating, and a table.

A spacious lobby with a sectional sofa, a coffee table, and a round table with chairs. There is a large abstract painting on the wall and a staircase in the background.

14. AC Hotel by Marriott St. Louis Chesterfield

13.8 km from Lewis and Clark Trail Trailhead

Richard

₩204,982

₩237,766 total

includes taxes & fees

Nov 1 - Nov 2

A multi-story hotel with a stone facade and a covered entrance.

A modern living room with a wooden dining table, grey chairs, a sofa, and a coffee machine.

A compact hotel room with two beds, a desk with a chair, a television, a microwave, and a refrigerator.

A modern living room with a blue accent wall, a gray sofa, a dining table with chairs, and a coffee table.

15. WoodSpring Suites St Peters-OFallon

13.6 km from Lewis and Clark Trail Trailhead

Joel

₩102,090

₩120,874 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio area with a stone fire pit, wicker furniture, and a covered seating area with a view of the building's interior.

A hotel room with a large bed, bedside lamps, a TV, a desk, and a bathroom.

A multi-story hotel with a brick facade, a covered outdoor seating area with a fire feature, and a sign indicating it is a Marriott property.

A modern kitchen with wooden cabinets, a stainless steel countertop, and various appliances including a coffee maker and a rice cooker.

16. TownePlace Suites by Marriott St. Louis Chesterfield

5.8 km from Lewis and Clark Trail Trailhead

Thomas

₩169,824

₩199,312 total

includes taxes & fees

Nov 20 - Nov 21

A modern kitchen with stainless steel appliances, a central island with stools, and a wine cooler.

A spacious lobby with a seating area, a reception desk, and a kitchen area.

A Hilton Garden Inn with a brick facade, a covered entrance, and landscaped gardens.

A swimming pool with a lifebuoy on the wall, poolside chairs, and a sign with pool rules.

17. Hilton Garden Inn Chesterfield

13.2 km from Lewis and Clark Trail Trailhead

Samantha

₩140,293

₩163,249 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a door, and a wall with a road map mural.

An indoor swimming pool with clear water, surrounded by chairs and a covered area.

A reception area with a sliding glass door, a reception desk, and a window with plants.

A kitchenette with a coffee machine, a coffee dispenser, and a coffee maker.

18. Super 8 by Wyndham St Charles

19.6 km from Lewis and Clark Trail Trailhead

Patrick

₩106,351

₩122,227 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen area with a breakfast bar, a coffee machine, and a refrigerator displaying menu options.

A pool area with a blue pool lift chair, a pool user capacity sign, and a tiled wall.

A coffee station with two coffee machines and a display of coffee pods and cups.

A Holiday Inn Express & Suites building with a brick facade, a covered entrance, and a numbered address.

19. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

10.3 km from Lewis and Clark Trail Trailhead

Terry

₩146,416

₩170,375 total

includes taxes & fees

Oct 25 - Oct 26

A modern kitchen with white cabinets, a central island, and a patterned rug.

A hotel reception area with two counters, a vending machine, and a display cabinet with snacks.

A swimming pool with lounge chairs and a fence.

A modern living room with a sofa, ottoman, and coffee table, a dining area with a table and chairs, and a kitchen with a refrigerator and microwave.

20. Homewood Suites by Hilton St. Louis-Chesterfield

15.1 km from Lewis and Clark Trail Trailhead

Sekar Reddy

₩145,950

₩169,284 total

includes taxes & fees

Oct 27 - Oct 28

View all properties

Compare popular hotels close to Lewis and Clark Trail Trailhead

Property	Property class	Guest rating
Sleep Inn & Suites O'Fallon MO - Technology Drive	9.0 Wonderful 1,146 reviews	View
Holiday Inn Express St. Louis West - O'Fallon by IHG	8.4 Very good 1,001 reviews	View
Drury Plaza Hotel St. Louis Chesterfield	9.6 Exceptional 1,301 reviews	View
The Wildwood Hotel	9.2 Wonderful 1,682 reviews	View
Hyatt Place St. Louis/Chesterfield	9.6 Exceptional 1,008 reviews	View

Hotels recommended for families near Lewis and Clark Trail Trailhead

Holiday Inn Express St. Louis West - O'Fallon by IHG

O'Fallon

₩123,788

₩146,008 total

includes taxes & fees

Oct 25 - Oct 26

Sleep Inn & Suites O'Fallon MO - Technology Drive

O'Fallon

₩109,391

₩129,026 total

includes taxes & fees

Nov 10 - Nov 11

A multi-story hotel with a central entrance featuring a covered patio area.

A hotel room with a desk, chair, sofa, and a window with curtains.

A hotel with a swimming pool, outdoor seating, and a covered patio area.

A hotel lobby with a sectional sofa, a fireplace, a flat-screen TV, and framed artwork on the walls.

Staybridge Suites O'Fallon Chesterfield by IHG

O'Fallon

₩142,422

₩167,985 total

includes taxes & fees

Oct 25 - Oct 26

TownePlace Suites by Marriott St. Louis Chesterfield

Chesterfield

₩170,374

₩199,956 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with a stone fireplace, seating area, and a bar with high stools.

A hotel pantry stocked with beverages and snacks, a refrigerated display case, and a sign reading "The Market".

A hotel lobby with a seating area featuring two armchairs, a round coffee table, and a flat-screen TV mounted on a wooden wall.

A multi-story hotel with a central entrance, large windows, and a well-maintained lawn.

Residence Inn by Marriott O'Fallon

O'Fallon

₩162,388

₩191,537 total

includes taxes & fees

Nov 20 - Nov 21

A spacious lobby with a high ceiling, a central seating area with sofas and a coffee table, and a large window providing natural light.

A spacious lobby with a fireplace, comfortable seating, a large painting, and a view of the kitchen area.

A hotel with a covered entrance, multiple flags, and a well-maintained lawn.

A shop with a variety of snacks and beverages, including a refrigerated section with drinks and a display of packaged snacks.

Hilton Garden Inn St. Louis/O'Fallon MO

O'Fallon

₩142,968

₩169,523 total

includes taxes & fees

Nov 19 - Nov 20

A hotel room with a bed, bedside tables, a desk, a TV, and a window with curtains.

A picnic area with a table and benches, surrounded by grass and trees.

A gym with a treadmill, elliptical, stationary bike, and a rack of dumbbells.

A modern dining area with a brick fireplace, yellow and blue chairs, and a blue sofa.

Comfort Inn & Suites Chesterfield - St. Louis

Chesterfield

₩112,008

₩134,995 total

includes taxes & fees

Oct 27 - Oct 28

An outdoor patio area with wicker furniture and a central fire feature.

A modern hotel lobby with a reception desk, seating area, and a television screen displaying a map.

A hotel room with a bed, a sofa, a desk, and a chair.

A modern hotel lobby with a bar area, seating arrangements, and a reception desk.

Courtyard by Marriott St. Louis Chesterfield

Chesterfield

₩142,555

₩165,881 total

includes taxes & fees

Nov 19 - Nov 20

Top Lewis and Clark Trail Trailhead Hotel Reviews

Comfort Suites St Charles - St Louis

10/10 Excellent

"I truly enjoyed my stay. The staff was excellent. I ran into a problem. They addressed it right away. Everyone was pleasant. I will say again."

Ameristar Casino Resort and Spa

10/10 Excellent

"Experience was Great! Room was clean , always a perfect fit."

Sonesta ES Suites St. Louis - Chesterfield

10/10 Excellent

"From the moment I checked in and was greeted by Omar, my experience was excellent. I had a very good sleep on the comfortable king-sized bed. The room was spotless. It's so convenient that there is a full fridge with freezer, and this is a dog friendly place. The breakfast was outstanding with many hot options and many beverage options. I even received a follow-up call to make sure that I enjoyed my stay."

Drury Plaza Hotel St. Louis Chesterfield

10/10 Excellent

"Staff members friendly. Evening hors d’oeuvres and breakfast was amazing. Room spacious, beds comfortable. Convenient to the highway."

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent

"Very friendly staff. Good breakfast"

The Wildwood Hotel

10/10 Excellent

"The place is nice and clean. Staff is friendly. Everything a person needs is within walking distance and a B&B movie theatre is right across the street."

Sleep Inn & Suites O'Fallon MO - Technology Drive

8/10 Good

"The room was very clean and comfortable. The breakfast was so-so, the biscuits were great. I asked the front desk for a recommendation for somewhere local to eat dinner and they told me that across the street there were places to eat and fast food down the road. I ended up getting lost and ended up a one of the restaurants across the street, which was very expensive and to much food. The location of this hotel is hard to find. And when I checked in there was to much on top of the counter. After a long day of driving it was way too much to try and take it all in."

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

10/10 Excellent

"I love it thank you ."

Other attractions near Lewis and Clark Trail Trailhead

A wooden dock extending into a pond with lily pads, surrounded by lush greenery and a clear blue sky.

August A. Busch Memorial Conservation Area

8.6/10 (7 reviews)

Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savor the top-notch restaurants.

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A chain-link fence with a red sign that reads "REMEMBRANCE DAY" and a date "09-11-01".

9-11 Memorial

7.6/10 (44 reviews)

Learn about the local history of O'Fallon when you spend time at 9-11 Memorial. While in this family-friendly area, you can savor the top-notch restaurants.

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Weldon Spring Site Interpretive Center

8.2/10 (14 reviews)

You can spend time browsing the exhibits at Weldon Spring Site Interpretive Center during your trip to Weldon Spring Heights. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.

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Hamburg Trail Trailhead

You can take time to visit Hamburg Trail Trailhead during your travels to Hamburg.

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Missouri Bluffs Golf Course

7.6/10 (40 reviews)

Enjoy a round of golf in Weldon Spring Heights at Missouri Bluffs Golf Course. Experience the great live music or attend a sporting event in this family-friendly area.

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St. Louis Premium Outlets

8.8/10 (369 reviews)

You can enjoy retail therapy at St. Louis Premium Outlets during your stay in Chesterfield. Discover the top-notch restaurants and great live music in this family-friendly area.

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Golf Headquarters Family Golfplex

You can take time to visit Golf Headquarters Family Golfplex during your travels to O'Fallon. Visit the shops in this family-friendly area, or simply enjoy its restaurants.

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Babler State Park

8.6/10 (59 reviews)

You can take time to visit Babler State Park during your travels to Chesterfield. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.

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Frequently asked questions

What's the area like around Lewis and Clark Trail Trailhead?

Lewis and Clark Trail Trailhead is located in Weldon Spring Heights. You'll find 27 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay close to Lewis and Clark Trail Trailhead?

Sleep Inn & Suites O'Fallon MO - Technology Drive is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 2 mi (3.2 km) from Lewis and Clark Trail Trailhead. Other good options around the area include Holiday Inn Express & Suites St. Louis - Chesterfield by IHG and Sonesta ES Suites St. Louis - Chesterfield.

How many hotels can I expect to find near Lewis and Clark Trail Trailhead?

Expedia has 27 hotels and other accommodations a few miles from Lewis and Clark Trail Trailhead.

If I need to cancel the hotel reservation for my stay near Lewis and Clark Trail Trailhead, will I receive a refund?

Yes, most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available near Lewis and Clark Trail Trailhead.

Where can I learn more about changing or cancelling my trip in the area near Lewis and Clark Trail Trailhead?

For more details about picking new dates or cancelling your stay near Lewis and Clark Trail Trailhead, click here.

What can I see and do near Lewis and Clark Trail Trailhead?

Explore nature at August A. Busch Memorial Conservation Area and Hamburg Trail Trailhead. Missouri Bluffs Golf Course, Babler State Park, and Golf Headquarters Family Golfplex are worth a stop while you're in the area. St. Louis Premium Outlets and 9-11 Memorial are both worth a visit while you're checking out the area.

Find hotels near Lewis and Clark Trail Trailhead, St. Louis from ₩120,874

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Lewis and Clark Trail Trailhead hotels

1. Sleep Inn & Suites O'Fallon MO - Technology Drive

2. Holiday Inn Express St. Louis West - O'Fallon by IHG

3. Drury Plaza Hotel St. Louis Chesterfield

4. The Wildwood Hotel

5. Hyatt Place St. Louis/Chesterfield

6. Drury Inn & Suites St. Louis St. Peters

7. Residence Inn by Marriott St. Louis Chesterfield

8. SpringHill Suites by Marriott St. Louis Chesterfield

9. Holiday Inn Express & Suites St Peters by IHG

10. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

11. Hampton Inn St. Louis/Chesterfield

12. Courtyard by Marriott St. Louis St. Peters

13. DoubleTree by Hilton Hotel St. Louis - Chesterfield

14. AC Hotel by Marriott St. Louis Chesterfield

15. WoodSpring Suites St Peters-OFallon

16. TownePlace Suites by Marriott St. Louis Chesterfield

17. Hilton Garden Inn Chesterfield

18. Super 8 by Wyndham St Charles

19. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

20. Homewood Suites by Hilton St. Louis-Chesterfield

Compare popular hotels close to Lewis and Clark Trail Trailhead

Hotels recommended for families near Lewis and Clark Trail Trailhead

Holiday Inn Express St. Louis West - O'Fallon by IHG

Sleep Inn & Suites O'Fallon MO - Technology Drive

Staybridge Suites O'Fallon Chesterfield by IHG

TownePlace Suites by Marriott St. Louis Chesterfield

Residence Inn by Marriott O'Fallon

Hilton Garden Inn St. Louis/O'Fallon MO

Comfort Inn & Suites Chesterfield - St. Louis

Courtyard by Marriott St. Louis Chesterfield

Top Lewis and Clark Trail Trailhead Hotel Reviews

Comfort Suites St Charles - St Louis

Ameristar Casino Resort and Spa

Sonesta ES Suites St. Louis - Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Embassy Suites by Hilton St. Louis St. Charles

The Wildwood Hotel

Sleep Inn & Suites O'Fallon MO - Technology Drive

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Other attractions near Lewis and Clark Trail Trailhead

August A. Busch Memorial Conservation Area

9-11 Memorial

Weldon Spring Site Interpretive Center

Hamburg Trail Trailhead

Missouri Bluffs Golf Course

St. Louis Premium Outlets

Golf Headquarters Family Golfplex

Babler State Park

Frequently asked questions