Find hotels in O Brien, FL from ₩65,429

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Our top choices for O Brien hotels

1. Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (720 reviews)
"Loved staying here!! Will definitely visit again!! "
United States
Ashley
The price is ₩108,040
₩121,545 total
includes taxes & fees
Jun 7 - Jun 8
Super 8 by Wyndham Lake City

2. Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,003 reviews)
"Was ok"
United States
James
The price is ₩95,178
₩107,076 total
includes taxes & fees
Jun 14 - Jun 15
Days Inn by Wyndham Lake City I-10

3. Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (516 reviews)
"Wonderful place to stay"
United States
Tamela
The price is ₩140,210
₩157,736 total
includes taxes & fees
Jun 21 - Jun 22
Hampton Inn & Suites Alachua I-75

4. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,005 reviews)
"The staff were amazing, great location, big rooms, great breakfast"
United States
Brittani
The price is ₩151,317
₩170,231 total
includes taxes & fees
Jun 14 - Jun 15
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

5. Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,010 reviews)
"Great stay - easy - accommodating - quiet!"
United States
Paula
The price is ₩164,588
₩185,161 total
includes taxes & fees
Jun 9 - Jun 10
Comfort Suites Lake City

6. Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.6 out of 10, Good, (615 reviews)
"REALLY NICE PLACE, VERY CLEAN, WONDERFUL STAFF"
United States
Caroline
The price is ₩98,280
₩110,564 total
includes taxes & fees
Jun 4 - Jun 5
Palms Garden Inn

7. Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very Good, (1,000 reviews)
"Convenient to restaurants "
United States
Bruce
The price is ₩115,213
₩129,615 total
includes taxes & fees
Jun 29 - Jun 30
Quality Inn Lake City

8. Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,000 reviews)
"Breakfast menu was fresh, the room was clean, and the staff friendly and professional."
United States
Claire
The price is ₩181,580
₩204,278 total
includes taxes & fees
Jun 14 - Jun 15
Hampton Inn & Suites Lake City

9. La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1,110 reviews)
"Enjoyed our stay"
United States
Tammie
The price is ₩133,586
₩150,285 total
includes taxes & fees
Jun 4 - Jun 5
La Quinta Inn & Suite by Wyndham Lake City

10. Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,064 reviews)
"Great staff, good room, lovely breakfast"
United States
berendina
The price is ₩166,982
₩187,855 total
includes taxes & fees
Jun 4 - Jun 5
Best Western Plus Lake City

11. Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,000 reviews)
"We stopped for one night. We have stayed here before when visiting. The staff is always helpful and accommodating ."
United States
William
The price is ₩107,586
₩121,053 total
includes taxes & fees
Jun 9 - Jun 10
Americas Best Value Inn Lake City

12. Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (790 reviews)
"Great place to stay we will be back soon. "
United States
William
The price is ₩198,314
₩223,103 total
includes taxes & fees
Jul 2 - Jul 3
Home2 Suites by Hilton Lake City

13. Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (239 reviews)
"Excellent stay. Great breakfast. "
United States
Janet
The price is ₩180,067
₩202,576 total
includes taxes & fees
Jun 4 - Jun 5
Fairfield Inn & Suites Lake City

14. The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (190 reviews)
"Great property! Beautiful renovated!"
United States
Brandi
The price is ₩224,706
₩252,795 total
includes taxes & fees
Jun 15 - Jun 16
The Blanche

15. Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
White Springs
7.2 out of 10, Good, (676 reviews)
"Was great!! Clean rooms and peaceful.. Would stay here again and again.."
United States
Anthony
The price is ₩109,311
₩120,241 total
includes taxes & fees
Jun 29 - Jun 30
Quality Inn White Springs Suwanee

16. Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,008 reviews)
"Clean helpful staff and breakfast was good.parking good also"
United States
John
The price is ₩164,936
₩185,561 total
includes taxes & fees
Jun 21 - Jun 22
Tru by Hilton Lake City

17. Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,000 reviews)
"Great for a short stay and clean"
United States
Brizheet
The price is ₩100,797
₩113,397 total
includes taxes & fees
Jun 7 - Jun 8
Days Inn by Wyndham Lake City I-75

18. Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,000 reviews)
"Staff friendly and helpful. Beds very comfortable."
United States
Candice
The price is ₩172,501
₩194,063 total
includes taxes & fees
Jun 14 - Jun 15
Holiday Inn & Suites Lake City by IHG

19. Regal Inn

Regal Inn
2.5 star property
Lake City
8.4 out of 10, Very Good, (597 reviews)
"older hotel really nicely renovated. Very charmful, comfortable beds. I stayed there because of the reviews and they were accurate. No special amenities' but great value."
United States
William
The price is ₩93,877
₩105,604 total
includes taxes & fees
Jun 8 - Jun 9
Regal Inn

20. Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75
2.5 star property
Lake City
5.0 out of 10, (1,001 reviews)
"Pool was clean, so was the room"
United States
Shannon
The price is ₩91,320
₩102,744 total
includes taxes & fees
Jun 14 - Jun 15
Baymont by Wyndham Lake City I-75
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

More cheap stays in O Brien

Frequently asked questions

Where is the best place to stay in O Brien?
La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Comfort Suites Lake City. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
Where can I learn more about changing or cancelling my trip to O Brien?
To access more information about picking new dates or cancelling your trip to O Brien, click here.
Where is the best hotel to stay near Ichetucknee Springs State Park?
Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.
What are some accommodations with pools in O Brien?
La Quinta Inn & Suite by Wyndham Lake City: Features on-the-go, an indoor pool, and free self parking. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Comfort Suites Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
What's the best hotel for staying near Gainesville Regional Airport (GNV)?
Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and Wes Skiles Peacock Springs State Park in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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