Otay Mesa, CA

San Diego

A city skyline with high-rise buildings and a bridge over a body of water.
An aerial view of a densely populated city with a mix of residential and commercial buildings, surrounded by greenery and a clear sky.
A hillside town with a winding road, a bridge in the distance, and a river in the foreground.

Stay near popular Otay Mesa attractions


Otay Mesa Hotel Deals

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is ₩243,338 per night from Jul 19 to Jul 20
₩243,338
₩334,703 total
Jul 19 - Jul 20
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,287 reviews)
"Balcony view was amazing. No microwave. Friendly staff. Clean room.Walking distance to Seaport Village was close by, along with other attractions. Will plan on staying here again."

Reviewed on Jul 10, 2026

Wyndham San Diego Bayside
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is ₩421,726 per night from Aug 9 to Aug 10
₩421,726
₩564,687 total
Aug 9 - Aug 10
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,724 reviews)
"Unexpected $50 nightly per car parking fee and an add on $50 per day resort fee. It's a good place but no longer worth the add on fees."

Reviewed on Jul 10, 2026

Paradise Point Resort & Spa
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is ₩251,087 per night from Jul 19 to Jul 20
₩251,087
₩364,056 total
Jul 19 - Jul 20
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (4,016 reviews)
"Clean room. The location was perfect for our visit(going to Petco park). The pool is heated which I wish I would have known ahead of time, it looked great. Everyone was friendly."

Reviewed on Jul 10, 2026

Hard Rock Hotel San Diego
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

2.5 out of 5
2485 Hotel Circle Place San Diego CA
The price is ₩192,133 per night from Aug 2 to Aug 3
₩192,133
₩220,832 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (2,798 reviews)
"Room was double booked, staff was very welcoming"

Reviewed on Jul 10, 2026

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
The price is ₩396,531 per night from Aug 9 to Aug 10
₩396,531
₩539,501 total
Aug 9 - Aug 10
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,238 reviews)
"Overall, this is a wonderful place to stay. I'm giving it 4 stars instead of 5 only because housekeeping forgot to replenish the shampoo and body wash when they serviced the room. Aside from that oversight, everything was great."

Reviewed on Jul 10, 2026

Bahia Resort Hotel
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
The price is ₩318,122 per night from Aug 5 to Aug 6
₩318,122
₩365,657 total
Aug 5 - Aug 6
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
9.2/10 Wonderful! (3,742 reviews)
"Great place to stay! Beach right across from hotel for the kids."

Reviewed on Jul 10, 2026

Bay Club Hotel & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Petco Park and Seaport Village are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Spreckels Theater is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.



Otay Mesa, CA