Find hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very Good, (1,810 reviews)
"Clean rooms, friendly staff stay here every year"
JESUS
The price is ₩208,637
₩237,325 total
includes taxes & fees
Aug 26 - Aug 27
2. Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,016 reviews)
"Very quiet and friendly staff excellent breakfast"
Mia
The price is ₩173,621
₩197,494 total
includes taxes & fees
Aug 3 - Aug 4
3. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista6.5 km from Otay Mesa
9.8 out of 10, Exceptional, (1,087 reviews)
"We really enjoyed the cleanliness and the manager Karen was excellent 😊"
Deniece
The price is ₩300,700
₩331,354 total
includes taxes & fees
Aug 16 - Aug 17
4. Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
8.8 out of 10, Excellent, (1,349 reviews)
"Great stay"
Luis
The price is ₩182,535
₩207,633 total
includes taxes & fees
Aug 16 - Aug 17
5. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,958 reviews)
"Nice location and clean hotel."
Abdelghani
The price is ₩249,381
₩274,805 total
includes taxes & fees
Aug 16 - Aug 17
6. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, Very Good, (1,620 reviews)
"clean room, helpful staff, good breakfast, easy parking"
Xiaolei
The price is ₩173,208
₩190,875 total
includes taxes & fees
Aug 23 - Aug 24
7. Studio 6 Suites San Ysidro, CA -San Diego South Bay
Studio 6 Suites San Ysidro, CA -San Diego South Bay6.9 km from Otay Mesa
8.0 out of 10, Very Good, (1,721 reviews)
"Everyone super nice and super clean"
Alan
The price is ₩129,851
₩147,957 total
includes taxes & fees
Aug 5 - Aug 6
8. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,347 reviews)
"Rooms are clean, friendly staff and wonderful breakfast"
yu
The price is ₩217,595
₩239,349 total
includes taxes & fees
Aug 25 - Aug 26
9. Valli Hi Motel
Valli Hi Motel7.9 km from Otay Mesa
8.2 out of 10, Very Good, (1,078 reviews)
"Good stay for the price. The Staff was very friendly and accommodating."
elizabeth E
The price is ₩131,940
₩150,339 total
includes taxes & fees
Jul 29 - Jul 30
10. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,691 reviews)
"Comfortable and close to food and highway."
Andrea
The price is ₩185,669
₩204,235 total
includes taxes & fees
Aug 16 - Aug 17
11. SureStay Hotel by Best Western Chula Vista San Diego Bay
SureStay Hotel by Best Western Chula Vista San Diego Bay14.7 km from Otay Mesa
8.0 out of 10, Very Good, (1,796 reviews)
"Very good location and good breakfast included."
UBALDO
The price is ₩116,880
₩128,796 total
includes taxes & fees
Aug 5 - Aug 6
12. Hercor Hotel - Urban Boutique
Hercor Hotel - Urban Boutique13.6 km from Otay Mesa
8.8 out of 10, Excellent, (1,480 reviews)
"Great hotel,"
Keane
The price is ₩159,533
₩175,798 total
includes taxes & fees
Aug 10 - Aug 11
13. The Rambler Hotel
The Rambler Hotel14.8 km from Otay Mesa
9.0 out of 10, Wonderful, (2,184 reviews)
"We LOVED our stay"
Juanita
The price is ₩195,506
₩226,189 total
includes taxes & fees
Aug 16 - Aug 17
14. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,706 reviews)
"Great clean hotel close to the airport. Would definitely stay again."
Aimee
The price is ₩237,844
₩273,389 total
includes taxes & fees
Aug 23 - Aug 24
15. Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego24.6 km from Otay Mesa
8.4 out of 10, Very Good, (1,013 reviews)
The price is ₩228,188
₩251,007 total
includes taxes & fees
Aug 9 - Aug 10
16. Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.4 out of 10, Very Good, (3,614 reviews)
"Perfect hotel for family fun."
Andre
The price is ₩237,492
₩347,135 total
includes taxes & fees
Aug 27 - Aug 28
17. SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (717 reviews)
"We had a great stay at this beautiful property"
Jeannette
The price is ₩299,897
₩330,472 total
includes taxes & fees
Aug 9 - Aug 10
18. Holiday Inn Express San Diego South - National City by IHG
Holiday Inn Express San Diego South - National City by IHG16.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,005 reviews)
"Big rooms, comfortable bed, good buffet breakfast"
Leslie
The price is ₩202,499
₩223,140 total
includes taxes & fees
Aug 17 - Aug 18
19. Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (2,060 reviews)
"Lazy river and the food, great room great service"
Dale
The price is ₩181,062
₩216,676 total
includes taxes & fees
Aug 26 - Aug 27
20. WoodSpring Suites Santee - San Diego Northeast
WoodSpring Suites Santee - San Diego Northeast30.9 km from Otay Mesa
8.4 out of 10, Very Good, (183 reviews)
"Very nice and clean hotel and very friendly and helpful staff."
Joel
The price is ₩188,211
₩207,032 total
includes taxes & fees
Aug 5 - Aug 6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Pacific Beach
Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.
Mission Beach
Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
