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Our top choices for South Carolina Midlands hotels

A modern bar area with a central island, bar stools, and a television.

1. Cambria Hotel Columbia Downtown The Vista

Downtown Columbia

Thomas

₩159,391 total

includes taxes & fees

Nov 23 - Nov 24

A Holiday Inn Express & Suites hotel with a parking lot and a signboard.

2. Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

Columbia

Sharlene

₩148,835 total

includes taxes & fees

Nov 1 - Nov 2

A modern room with a large flat-screen TV mounted on a wooden wall, a desk with a chair, and a bench with a cushion.

3. Tru By Hilton Columbia Greystone

Columbia

Eddie

₩148,920 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor patio with a stone fire pit, seating, and a covered area with lights.

4. Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

Leslie

₩162,020 total

includes taxes & fees

Nov 22 - Nov 23

A spacious indoor area with a long table, multiple chairs, and a seating area with sofas and a TV.

5. The Lantern Hotel Columbia

Downtown Columbia

Theresa

₩227,152 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor patio area with wicker furniture, a stone fireplace, and a flat-screen TV mounted above.

6. Hampton Inn Columbia I-26/Harbison Blvd.

St. Andrews

Robert

₩156,821 total

includes taxes & fees

Nov 23 - Nov 24

A modern living room with a grey sofa, a wooden bookshelf, a large wall clock, a fireplace, and a staircase.

7. Country Inn & Suites by Radisson, Columbia Airport, SC

Cayce

Jacqueline

₩144,345 total

includes taxes & fees

Nov 15 - Nov 16

An outdoor patio with a bar area, seating, and a grill station.

8. Tru By Hilton Columbia Downtown

Downtown Columbia

Jennifer

₩144,871 total

includes taxes & fees

Nov 15 - Nov 16

A modern living room with a blue cabinet, a blue sofa, a round coffee table, and patterned ottomans.

9. Hotel Trundle

Downtown Columbia

Nicolas

₩250,907 total

includes taxes & fees

Nov 16 - Nov 17

An outdoor seating area with a stone fireplace, a flat-screen TV mounted above it, and a view of the cityscape in the background.

10. Courtyard by Marriott Columbia Downtown at USC

Downtown Columbia

maggie

₩150,172 total

includes taxes & fees

Nov 28 - Nov 29

An outdoor patio with a fire pit, seating, and a grill.

11. LivSmart Studios by Hilton Columbia Greystone

Columbia

Robertson

₩151,449 total

includes taxes & fees

Nov 22 - Nov 23

A two-story brick house with a porch, a flag, and a well-maintained lawn.

12. Graduate by Hilton Columbia SC

Downtown Columbia

Heather Massey

₩209,417 total

includes taxes & fees

Nov 25 - Nov 26

A patio area with wicker furniture, a central fire pit, and outdoor umbrellas.

13. Hilton Garden Inn Columbia Airport

West Columbia

SHERI

₩151,438 total

includes taxes & fees

Nov 27 - Nov 28

A spacious lobby with a central seating area, a shop, and large potted plants.

14. Hilton Garden Inn Columbia/Harbison

Columbia

Brenda

₩126,610 total

includes taxes & fees

Nov 15 - Nov 16

A reception area with a cityscape mural, two reception desks, and a modern design.

15. La Quinta Inn by Wyndham Columbia SE / Fort Jackson

Columbia

Sunta

₩132,504 total

includes taxes & fees

Nov 8 - Nov 9

A modern building entrance with a brick pathway leading to a glass door.

16. Hampton Inn Columbia-I-26 Airport

West Columbia

Heidi

₩130,954 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel with a glass facade, palm trees, and a landscaped garden with purple flowers.

17. Hyatt Place Columbia/Harbison

Irmo

Anihya

₩124,711 total

includes taxes & fees

Nov 19 - Nov 20

A rooftop bar with tables and chairs, overlooking a cityscape at dusk.

18. Sheraton Columbia Downtown Hotel

Downtown Columbia

Bart

₩175,187 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a high ceiling, a central seating area with a patterned rug, and a fireplace.

19. Holiday Inn Express Columbia West - Lexington by IHG

Lexington

Michael

₩161,853 total

includes taxes & fees

Nov 22 - Nov 23

A Hampton Inn & Suites with a rooftop pool, outdoor seating, and a modern architectural design.

20. Hampton Inn & Suites Columbia Killian Road

Columbia

William

₩169,473 total

includes taxes & fees

Nov 10 - Nov 11

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Vacation Rentals in South Carolina Midlands

Aparthotel

A multi-story hotel with a modern design, featuring a prominent 'STUDIOS' sign on the facade.

StudioRes by Marriott Columbia Harbison

Columbia

"Staff is great. Very clean and convenient to everything."

Aparthotel

A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.

stayAPT Suites Columbia-Irmo Harbison

Irmo

"Hands down the cleanest,best priced affordable place I've ever had the pleasure of staying.feels more like home than a hotel.id give them 10 stars if I could.no complains what so ever."

Apartment

A living room with a gray sofa, a coffee table, a patterned rug, a bed, and a brick wall.

Backyard Oasis w/ Pool: Sunny Sumter Studio!

Sumter

"The studio was very clean, decorated nicely, and cozy. The location is quiet and easy to find. Communication was punctual. I really enjoyed my stay"

Cottage

A covered outdoor deck with wicker furniture and a red door.

Step-free Home w/ Fire Pit - 3 Miles to Usc!

Rosewood

"Cute Bungalow!!!! We loved our stay. It was clean, safe, loads of towels, plenty of kitchen supplies, super comfortable beds, and awesome communication from the hosts. I highly recommend this house. I will book again when I return to Columbia!"

Aparthotel

A modern courtyard with white furniture, a central seating area, and a small lawn.

stayAPT Suites Rock Hill

Rock Hill

"The check-in was smooth the room was okay the bathroom could have been a little cleaner the floors could have been a little cleaner but the stay was okay I was able to sleep well"

Cottage

A modern kitchen with blue cabinets, a central island, and a spiral staircase leading to an upper level.

Greenwood Getaway w/ Furnished Patio & Lake View

Greenwood

"wonderful hosts, pet friendly, very clean"

Apartment

A residential street with a sidewalk, a white picket fence, and houses with green shutters.

Aiken Apt w/ Garden-view Balcony: Half-mi to Dtwn!

Aiken

"Absolutely LOVED our stay at this property! Everything was perfect from the location, cleanliness, decor, and owner! I would definitely stay here again and recommend to anyone! Thanks for being an amazing host especially after returning from Jamaica! ❤️❤️❤️❤️❤️❤️"

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Stay near popular South Carolina Midlands attractions

A large sign for 'Fury 325' with a roller coaster in the background.

Carowinds Theme Park

8.8/10 (962 reviews)

Choose from 13 roller coasters, chase your friends in a bumper car, enjoy the water slides and beaches of Boomerang Bay, and walk with dinosaurs.

See properties

Learn more about South Carolina Midlands

With Revolutionary War sites, a charming capital city and lots of kayaking opportunities, this southern region is sure to delight.

See all hotels in South Carolina Midlands

A monument with a statue on top, in front of a large building with columns.

Top South Carolina Midlands Hotel Reviews

Howard Johnson by Wyndham Florence

10/10 Excellent

"Vonvi"

Hilton Garden Inn Columbia/Harbison

10/10 Excellent

"⭐️⭐️⭐️⭐️⭐️ Excellent Stay at Hilton Garden Inn! I had a wonderful experience at the Hilton Garden Inn! From the moment I arrived, the staff was friendly, welcoming, and very professional. The food was absolutely delicious, served fresh and hot, and everything was wonderful! The rooms were very clean, comfortable, and well-maintained, which made my stay even more enjoyable. The entire staff did an outstanding job making sure guests felt welcome and appreciated. I truly enjoyed my time at this hotel, and I want to thank everyone for their excellent hospitality and service. I highly recommend the Hilton Garden Inn to anyone looking for a clean, comfortable hotel with great food and wonderful service. I will definitely be returning again! Keep up the excellent work!"