Find hotels in South Carolina Midlands, SC
Go beyond your typical stay in South Carolina Midlands
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Family friendly
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Sep 11 - Sep 13Our top choices for South Carolina Midlands hotels
1. Hampton Inn & Suites Columbia Killian Road
Hampton Inn & Suites Columbia Killian RoadColumbia
Valerie
2. Holiday Inn Express North Augusta by IHG
Holiday Inn Express North Augusta by IHGNorth Augusta
Lynn G
3. Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham FlorenceFlorence
HOMERO
4. Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SCFlorence
Hector
5. Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
Melissa
7. Country Inn & Suites by Radisson, Columbia Airport, SC
Country Inn & Suites by Radisson, Columbia Airport, SCCayce
Liaisha
10. Springhill Suites by Marriott Columbia near Fort Jackson
Springhill Suites by Marriott Columbia near Fort JacksonColumbia
Rachel
11. Hampton Inn & Suites Lexington Columbia
Hampton Inn & Suites Lexington ColumbiaLexington
Alan
12. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHGFlorence
Christopher
13. La Quinta Inn by Wyndham Columbia NE/Fort Jackson
La Quinta Inn by Wyndham Columbia NE/Fort JacksonColumbia
Brianna
14. Hilton Garden Inn Columbia/Harbison
Hilton Garden Inn Columbia/HarbisonColumbia
Dolores
15. Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG
Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHGColumbia
Raymond
16. Fairfield Inn & Suites by Marriott Florence I-20
Fairfield Inn & Suites by Marriott Florence I-20Florence
leslie
17. Country Inn & Suites by Radisson, Aiken South
Country Inn & Suites by Radisson, Aiken SouthAiken
Monique
18. Wyndham Garden Columbia/Ft. Jackson
Wyndham Garden Columbia/Ft. JacksonColumbia
Spencer
20. Springhill Suites by Marriott Cheraw
Springhill Suites by Marriott CherawCheraw
Katie
Vacation Rentals in South Carolina Midlands
Apartment
Easy Access to I-77 & I-20: Columbia Duplex!
Easy Access to I-77 & I-20: Columbia Duplex!Columbia
"Good rental. The only downside was that there was a strong cigar odor the first two days. I also found a few uncleaned hairs lying around on the counter and bed. Other than that, it’s a good home for a quick trip. Especially if you’re visiting for Fort Jackson purposes."
Aparthotel
StudioRes by Marriott Columbia Harbison
StudioRes by Marriott Columbia HarbisonColumbia
"Probably one of the best hotels I’ve been to in a while, especially considering the price!"
Aparthotel
stayAPT Suites Columbia-Irmo Harbison
stayAPT Suites Columbia-Irmo HarbisonIrmo
"Staff on property were very friendly and Professional."
Aparthotel
The Hangar Lofts Hotel
The Hangar Lofts HotelRosewood
"Clean convenient and great hospitality. "
Cottage
3 Mi to Marina: Quiet Getaway w/ Deck in Lexington
3 Mi to Marina: Quiet Getaway w/ Deck in LexingtonLexington
"Very cozy home lots of room and kept clean!"
Aparthotel
stayAPT Suites Rock Hill
stayAPT Suites Rock HillRock Hill
"The room was nice… but when you say you have a full kitchen I would at least expect a frying pan of a cookie sheet. I left salt and pepper for the next guest bc there was NOTHING… not even paper towels. If you want anything go buy it bc they do not offer anything…. This is BARE mimium i am surprise that Expedia uses them. Its a great concept but not well executed"
Cottage
Bright Hopkins Home w/ Game Room & Fire Pit!
Bright Hopkins Home w/ Game Room & Fire Pit!Hopkins
Apartment
Backyard Oasis w/ Pool: Sunny Sumter Studio!
Backyard Oasis w/ Pool: Sunny Sumter Studio!Sumter
"The studio was very clean, decorated nicely, and cozy. The location is quiet and easy to find. Communication was punctual. I really enjoyed my stay"
Cottage
Peaceful Camden Vacation Rental ~ 3 Mi to Town!
Peaceful Camden Vacation Rental ~ 3 Mi to Town!Camden
"Location was perfect for us. Very cozy, and clean. Hadn't been modernized, but it was in great shape. Nasolgic; felt like I was visiting my grandparents! Only having one bathroom was a bit challenging, but we made it work!"
Cottage
Gilbert Lakefront Retreat w/ Private Dock!
Gilbert Lakefront Retreat w/ Private Dock!Gilbert
"It was a great visit"
Cottage
Prosperity Vacation Rental ~ 1 Mi to Lake Murray!
Prosperity Vacation Rental ~ 1 Mi to Lake Murray!Hollands Landing
"The property had a lot of land. It was a peaceful, beautiful scenery. They had games in the house, ax throwing, corn hole outside & bonfire. Seeing the neighbors horses walk by was amazing. "
Cottage
Greenwood Getaway w/ Furnished Patio & Lake View
Greenwood Getaway w/ Furnished Patio & Lake ViewGreenwood
"Wonderful stay and would definitely stay again! Reasonable price for the luxury place with everything that you could ask for in a rental. Close to restaurants and bars if that is your thing and right near the lake with beautiful views!! We loved our stay!"
Cottage
Stunning Lakefront Retreat w/ Dock Access!
Stunning Lakefront Retreat w/ Dock Access!Greenwood
Apartment
Steps to Lake Greenwood: Waterfront Gem w/ Patio
Steps to Lake Greenwood: Waterfront Gem w/ PatioGreenwood
"Me and my family really enjoyed the property the view. Everything was nice. We really enjoyed it. Hopefully, we’ll be coming back soon."
Apartment
Upscale Home w/ Poker Room < 1 Mi to Golf!
Upscale Home w/ Poker Room < 1 Mi to Golf!Aiken
"This was a lovely home. Would definitely be interested in renting this property again."
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Stay near popular South Carolina Midlands attractions
University of South Carolina
9.0/10 (2,467 reviews)
Walk around the campus of University of South Carolina, a top university in Columbia. Experience the area's acclaimed theater scene or attend a sporting event.
Riverbanks Zoo and Garden
8.8/10 (1,195 reviews)
Why not meet the animals who call Riverbanks Zoo and Garden home during your trip to Columbia? You can attend a sporting event while in the area.
Williams Brice Stadium
8.8/10 (938 reviews)
Catch an event at Williams Brice Stadium during your trip to Columbia. You can attend a sporting event while in the area.
Colonial Life Arena
8.8/10 (1,029 reviews)
Catch an event at Colonial Life Arena during your trip to Columbia. Experience the area's acclaimed theater scene or attend a sporting event.
Columbia Metropolitan Convention Center
8.4/10 (594 reviews)
Learn about the events happening at Columbia Metropolitan Convention Center during your trip to Columbia. Experience the area's acclaimed theater scene or attend a sporting event.
Learn more about South Carolina Midlands
Gourmet restaurants, shopping, and popular sights from Fort Jackson to Carowinds Theme Park—explore South Carolina Midlands, a destination also known for its college vibe.
See all hotels in South Carolina Midlands
Top South Carolina Midlands Hotel Reviews
Cambria Hotel Columbia Downtown The Vista
8/10 Good
"Jay was very helpful with the check in process and helped suggestions on where to dine in the area."
Howard Johnson by Wyndham Florence
10/10 Excellent
"Nice"
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
10/10 Excellent
"Clean room right off the highway. Very convenient"
Country Inn & Suites by Radisson, Columbia, SC
10/10 Excellent
"Everything was nice"
Delta Hotels by Marriott Columbia Northeast
10/10 Excellent
"I had a very comfortable stay. The staff was friendly. I enjoyed the Dos Amigos restaurant that was on the property as well."
More cheap stays in South Carolina Midlands
Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr Florence SC
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Wyndham Garden Columbia/Ft. Jackson
1539 Horseshoe Dr Columbia SC
Motel 6 Fort Mill, SC - Charlotte
3541 Foothills Way Fort Mill SC
Hotels in South Carolina Midlands with star-rating
4 Star Hotels
14 properties
3 Star Hotels
189 properties
2 Star Hotels
337 properties