St. Charles Vacation Rentals

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Vacation Rentals in St. Charles

Our top choices for St. Charles vacation rentals

White House at Grand Central

4.0 star property
8.6 out of 10, Excellent, (116)
"It was very clean and nicely decorated. The house is a cool old building. The AC worked great (important, as it was super muggy outside.) I was only there for a couple nights but I think it would have worked well for a longer stay. "
The price is ₩120,079
₩229,787 total
includes taxes & fees
Sep 8 - Sep 9
White House at Grand Central

Landing Downtown St. Louis

4.0 star property
8.0 out of 10, Very Good, (11)
"Good place!"
Landing Downtown St. Louis

Quaint St Louis Home ~ 6 Mi to Downtown!

3.0 star property
Quaint St Louis Home ~ 6 Mi to Downtown!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top St. Charles Hotel Reviews

Find out more about St. Charles

Find out more about St. Charles

Search for Vacation rentals in St. Charles on Expedia.co.uk! You can easily find your home rentals, villas, Vacation apartments in St. Charles using one of the methods below:

  • View our selection of featured Vacation rentals in St. Charles
  • Use the map to find apartments and other Vacation homes in the St. Charles neighbourhood you prefer
  • Enter your travel dates to view the best deals on Vacation rentals in St. Charles while they last

Look no further and take a look at our great range of rental properties in St. Charles!

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, you can find vacation rentals near popular attractions in St. Charles, or you can choose a secluded option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theater scene are some other things you might like to check out during your trip.

How many vacation rentals are there in St. Charles?

Expedia has 86 vacation rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and Lewis & Clark Boathouse and Nature Center.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned accommodations you can book for several days or more in St. Charles. Vacation rentals provide amenities such as laundry facilities and kitchens to help you enjoy your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for a family getaway.