Find hotels in East Prairie, MO from ₩87,416

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Nov 24 - Nov 25
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Compare 83 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2.0 star property
Sikeston
7.2 out of 10, Good, (1004)
"A great stay in every aspect. "
United States
Gertrude
The price is ₩92,525
₩105,456 total
includes taxes & fees
Nov 25 - Nov 26
Days Inn and Suites by Wyndham Sikeston
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 star property
Sikeston
9.0 out of 10, Wonderful, (429)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is ₩140,037
₩158,571 total
includes taxes & fees
Dec 14 - Dec 15
Hampton Inn Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
Sikeston
8.6 out of 10, Excellent, (440)
"Well maintained property. We’ll stop again should we need to."
United States
Janet DeJean
The price is ₩140,037
₩158,556 total
includes taxes & fees
Nov 28 - Nov 29
Holiday Inn Express & Suites Sikeston Southwest by IHG
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 star property
Sikeston
8.4 out of 10, Very Good, (1004)
"Very convenient and great breakfast "
United States
Duwaine
The price is ₩116,266
₩132,514 total
includes taxes & fees
Nov 30 - Dec 1
Best Western Plus Sikeston
Lobby
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

2.5 star property
Union City
9.2 out of 10, Wonderful, (303)
"Awesome room wonderful breakfast great staff"
United States
Thomas
The price is ₩123,783
₩146,991 total
includes taxes & fees
Dec 14 - Dec 15
Sleep Inn at Discovery Park of America
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
Sikeston
8.4 out of 10, Very Good, (711)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is ₩96,334
₩109,797 total
includes taxes & fees
Nov 25 - Nov 26
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
Sikeston
6.6 out of 10, (560)
"The room was good a/c kept it cold "
United States
Mary
The price is ₩85,023
₩96,909 total
includes taxes & fees
Nov 25 - Nov 26
Super 8 by Wyndham Sikeston/Miner Area
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1003)
"Everything was clean, staff was friendly "
United States
Matthew
The price is ₩113,251
₩130,182 total
includes taxes & fees
Nov 30 - Dec 1
Pear Tree Inn Sikeston
Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (610)
"Staff was great! Room was nice. "
United States
Lana
The price is ₩78,771
₩87,416 total
includes taxes & fees
Nov 25 - Nov 26
Super 8 by Wyndham Charleston/Sikeston East MO
Seasonal outdoor pool
Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51

2.5 star property
Union City
6.8 out of 10, (359)
"Easy to check in.. Clean Room..Lots of food options near by.. "
United States
Pooran
The price is ₩80,036
₩95,055 total
includes taxes & fees
Dec 23 - Dec 24
Hospitality House Union City I 69 / US 51
Exterior
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

2.5 star property
Sikeston
8.4 out of 10, Very Good, (277)
"Room was clean, breakfast was very good. "
United States
Connie
The price is ₩123,783
₩141,082 total
includes taxes & fees
Dec 1 - Dec 2
Comfort Inn & Suites Sikeston I-55
Lobby
Quality Inn Union City US 51

Quality Inn Union City US 51

2.5 star property
Union City
8.4 out of 10, Very Good, (482)
"The Staff for sure is what keeps me coming back! Plus the rooms are very clean!"
United States
Walter
The price is ₩98,776
₩117,297 total
includes taxes & fees
Dec 7 - Dec 8
Quality Inn Union City US 51
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1003)
"Clean room, great location and friendly staff"
United States
Mark
The price is ₩141,199
₩162,352 total
includes taxes & fees
Nov 28 - Nov 29
Drury Inn & Suites Sikeston, MO
Bar (on property)
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
Sikeston
9.2 out of 10, Wonderful, (37)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is ₩148,569
₩168,218 total
includes taxes & fees
Nov 30 - Dec 1
Fairfield Inn & Suites by Marriott Sikeston
Reception
Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City

2.5 star property
Union City
8.6 out of 10, Excellent, (547)
"Fantastic "
United States
Michael
The price is ₩105,896
₩125,754 total
includes taxes & fees
Nov 25 - Nov 26
Country Hearth Inn & Suites Union City
Terrace/patio
Hampton Inn Union City

Hampton Inn Union City

2.5 star property
Union City
9.4 out of 10, Exceptional, (160)
"Staff was very friendly, room was quiet, easy to get to. Room was clean and comfortable❤️"
United States
Diana
The price is ₩147,098
₩174,678 total
includes taxes & fees
Nov 30 - Dec 1
Hampton Inn Union City
Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 star property
Cairo
6.6 out of 10, (272)
"Break fast was excellent "
United States
Uma
The price is ₩101,145
₩112,250 total
includes taxes & fees
Nov 30 - Dec 1
Quality Inn Cairo I-57
Free daily buffet breakfast
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

2.5 star property
Union City
9.2 out of 10, Wonderful, (305)
"It was a great hotel! No complaints. Loved the front staff!"
United States
Felicia
The price is ₩140,037
₩166,294 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Express & Suites Union City by IHG
Bar (on property)
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3.0 star property
Sikeston
8.8 out of 10, Excellent, (6)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is ₩177,989
₩201,528 total
includes taxes & fees
Nov 30 - Dec 1
TownePlace Suites by Marriott Sikeston
Gazebo
Travel Inn

Travel Inn

2.5 star property
Marston
6.0 out of 10, (116)
"Had a great time loved it "
United States
Shyianne
Travel Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Big Oak Tree State Park

3.8/5 (8 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

10/10 Excellent
"Nice room and very clean. It would be nice if they had more exercise equipment."
Alex 1-night trip
Posted 6 days ago
Pear Tree Inn Sikeston

More cheap stays in East Prairie

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is ₩92,525 per night from Nov 25 to Nov 26
₩92,525
₩105,456 total
Nov 25 - Nov 26
includes taxes & fees
7.2/10 Good! (1,000 reviews)

Frequently asked questions

What's the best place for a stay in East Prairie?
Drury Inn & Suites Sikeston, MO, located 11.4 mi (18.4 km) from the heart of East Prairie, is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Days Inn and Suites by Wyndham Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in East Prairie.
If I need to cancel my hotel reservation in East Prairie, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in East Prairie.
Where can I learn more about changing or cancelling my trip to East Prairie?
To access more information about rescheduling or cancelling your trip to East Prairie, click here.
What's the best hotel for staying near Cape Girardeau Municipal Airport (CGI)?
Candlewood Suites Cape Girardeau is one of the top choices for your stay and is a popular hotel, featuring an indoor pool and free WiFi. It's located 4.4 mi (7 km) from Cape Girardeau Municipal Airport.
What's it like to stay in East Prairie?
Visitors are sure to enjoy all that East Prairie has to offer. There are 33 hotels and other accommodations in the surrounding area. Find out more about East Prairie.
What should I do while I'm visiting East Prairie?
The picturesque setting of Big Oak Tree State Park and Mississippi River exemplify the area's natural beauty. You'll also find Sikeston Depot Museum and New Madrid Historical Museum in the area. Check out what more to see and do in Expedia's East Prairie guide.
What's the weather like in East Prairie?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for East Prairie is 60 inches.

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