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Compare 14,831 hotels close to Mississippi River with room rates, reviews, and availability. Most hotels are fully refundable.

River's Edge Motel
Enjoy breathtaking views of the river and surrounding landscape from this balcony.

River's Edge Motel

2.0 star property
9.0 out of 10, Wonderful, (332)
"Great clean place to stay with friendly staff"
The price is ₩110,861
₩125,869 total
includes taxes & fees
Aug 7 - Aug 8
River's Edge Motel
The Eagles Nest Inn
Staircase leads to an upper level with a brick wall and polished wood handrail.

The Eagles Nest Inn

3.0 star property
9.4 out of 10, Exceptional, (8)
"It was very clean and very nice place to stay, has a very home and cozy feeling walking into the room."
The price is ₩137,190
₩155,759 total
includes taxes & fees
Aug 9 - Aug 10
The Eagles Nest Inn
Baymont by Wyndham Hannibal
Two beds with matching bedspreads and a nightstand with a lamp are featured in this stylish room.

Baymont by Wyndham Hannibal

2.5 star property
6.2 out of 10, (687)
"Very good breakfast, nice heated indoor pool, good exercise room, friendly staff. Highly recommended."
The price is ₩99,775
₩115,364 total
includes taxes & fees
Aug 7 - Aug 8
Baymont by Wyndham Hannibal
Riverside Inn Hannibal
Relax in this cozy space with a comfortable sofa, coffee table, and floor lamp.

Riverside Inn Hannibal

2.5 star property
9.4 out of 10, Exceptional, (129)
"Excellent service, room, and location."
The price is ₩174,881
₩248,598 total
includes taxes & fees
Aug 14 - Aug 15
Riverside Inn Hannibal
Best Western On The River
Swimmers can enjoy a rectangular pool surrounded by a tiled floor and multiple levels of balconies with railings.

Best Western On The River

2.5 star property
8.6 out of 10, Excellent, (1000)
"Nice location for seeing the area"
The price is ₩167,663
₩192,551 total
includes taxes & fees
Aug 17 - Aug 18
Best Western On The River
Lighthouse Inn & Suites
Deluxe Room | 1 bedroom, down comforters, blackout drapes, iron/ironing board

Lighthouse Inn & Suites

4.0 star property
9.0 out of 10, Wonderful, (15)
"Location is excellent! Close to historic downtown but far enough away to be quiet and peaceful! Very clean and decor is wonderful!"
The price is ₩198,302
₩227,777 total
includes taxes & fees
Aug 7 - Aug 8
Lighthouse Inn & Suites
Super 8 by Wyndham O'Fallon MO/St. Louis Area
Two beds with patterned bedspreads offer a comfortable stay, with a large window framing a view of a classical building and a cityscape photograph on the wall.

Super 8 by Wyndham O'Fallon MO/St. Louis Area

2.0 star property
6.8 out of 10, (956)
" The hotel was clean and obviously well cared for. "
The price is ₩97,765
₩115,314 total
includes taxes & fees
Aug 24 - Aug 25
Super 8 by Wyndham O'Fallon MO/St. Louis Area
Garden House Bed and Breakfast
Situated on a street corner, the Garden House features a two-story facade with a prominent porch and blue accents.

Garden House Bed and Breakfast

2.0 star property
8.6 out of 10, Excellent, (22)
"A beautiful 19th century mansion, decorated in period. Quiet and comfortable."
The price is ₩148,330
₩170,357 total
includes taxes & fees
Aug 19 - Aug 20
Garden House Bed and Breakfast
Economy Inn Wentzville
Staircase leads to an upper level, with a large potted plant and a sofa below.

Economy Inn Wentzville

2.0 star property
6.4 out of 10, (448)
"Peaceful"
The price is ₩97,003
₩110,050 total
includes taxes & fees
Aug 7 - Aug 8
Economy Inn Wentzville
Baymont by Wyndham Keokuk
Guests can relax in the lobby's seating area, surrounded by artwork and a warm wooden floor.

Baymont by Wyndham Keokuk

2.5 star property
6.2 out of 10, (454)
"Great staff and lovely building. "
The price is ₩76,078
₩85,210 total
includes taxes & fees
Sep 2 - Sep 3
Baymont by Wyndham Keokuk
Sleep Inn & Suites
Welcome to Sleep Inn & Suites, featuring a modern architectural design with a prominent tower and stone pillars.

Sleep Inn & Suites

2.5 star property
9.6 out of 10, Exceptional, (1000)
"Great stay!"
The price is ₩148,415
₩171,938 total
includes taxes & fees
Aug 31 - Sep 1
Sleep Inn & Suites
Motel 6 Hannibal, MO
Relax in the stylish lobby, featuring a comfortable sofa, armchair, and coffee table, with a large window offering a view.

Motel 6 Hannibal, MO

2.0 star property
7.4 out of 10, Good, (1000)
"Economical and comfortable, staff is anxious to serve. "
The price is ₩76,203
₩87,511 total
includes taxes & fees
Aug 10 - Aug 11
Motel 6 Hannibal, MO
Super 8 by Wyndham Hannibal
Relax in style on this patio, featuring a round table and four Adirondack chairs.

Super 8 by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (1002)
"Service was good and staff was friendly. The breakfast left some to be desired."
The price is ₩84,809
₩97,402 total
includes taxes & fees
Aug 11 - Aug 12
Super 8 by Wyndham Hannibal
LAKEVIEWINN
Experience the stylish entrance of our hotel, marked by a prominent sign and flanked by double doors with glass panels.

LAKEVIEWINN

2.5 star property
5.6 out of 10, (21)
"I felt like the place had permanent residents. Right outside my door was the community grill which had 5 or so people hanging out."
The price is ₩93,539
₩105,652 total
includes taxes & fees
Sep 1 - Sep 2
LAKEVIEWINN
Relax Inn Saint Charles
Welcome to our reception area, where friendly staff are available to assist with your stay. The reception desk offers a convenient check-in experience.

Relax Inn Saint Charles

2.0 star property
6.4 out of 10, (977)
"Great place for traveling."
The price is ₩87,253
₩100,272 total
includes taxes & fees
Aug 19 - Aug 20
Relax Inn Saint Charles
Comfort Inn & Suites - Hannibal
Relax in a hot tub surrounded by a cozy, enclosed space.

Comfort Inn & Suites - Hannibal

2.5 star property
7.6 out of 10, Good, (623)
"Great area and clean facilities"
The price is ₩135,943
₩160,287 total
includes taxes & fees
Aug 17 - Aug 18
Comfort Inn & Suites - Hannibal
Days Inn by Wyndham St Peters/St Charles
Welcome to the lobby, where guests can check in at the reception desk and relax in the seating area with a table and two chairs.

Days Inn by Wyndham St Peters/St Charles

2.0 star property
6.2 out of 10, (967)
"Nice hotel in a safe area. Normally do not stay at days inn, but this one was actually decent pricing and good area. Did not feel unsafe. "
The price is ₩93,054
₩106,967 total
includes taxes & fees
Sep 1 - Sep 2
Days Inn by Wyndham St Peters/St Charles
Extended Stay America Select Suites St Louis Earth City
StayAmerica hotel features a brick facade and a covered outdoor seating area with tables and chairs.

Extended Stay America Select Suites St Louis Earth City

2.5 star property
6.6 out of 10, (851)
"Great staff and amazing room"
The price is ₩99,761
₩120,118 total
includes taxes & fees
Aug 7 - Aug 8
Extended Stay America Select Suites St Louis Earth City
Days Inn by Wyndham Hannibal
Two single beds with white linens and a wooden headboard, complemented by a bedside table and lamp.

Days Inn by Wyndham Hannibal

2.0 star property
7.2 out of 10, Good, (185)
"I always stay here and have a very good experience"
The price is ₩92,499
₩106,246 total
includes taxes & fees
Aug 31 - Sep 1
Days Inn by Wyndham Hannibal
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
Relax in a stylish space with a large bed, wall art, and a cozy armchair.

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

3.0 star property
6.4 out of 10, (1012)
"Always a great stay ! "
The price is ₩90,698
₩110,867 total
includes taxes & fees
Aug 18 - Aug 19
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi River Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"Very clean and friendly staff. Breakfast was excellent"
Michelle 1-night trip
Posted 16 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Frequently asked questions

What's the area like around Mississippi River?

Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.

What's the best place to stay close to Mississippi River?

Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and 2 bars. You'll find it 82.1 mi (132.1 km) from Mississippi River. Other good options around the area include Clayton Plaza Hotel & Extended Stay and Drury Plaza Hotel St. Louis at the Arch.

If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.

Where can I learn more about changing or cancelling my trip in the area near Mississippi River?

For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.