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Compare hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
Alachua
9.4 out of 10, Exceptional, (1002)
"Great clean place to stay. "
United States
Mary
The price is ₩169,381
₩190,554 total
includes taxes & fees
Dec 1 - Dec 2
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Desk, blackout drapes, iron/ironing board, rollaway beds
Americas Best Value Inn Alachua

Americas Best Value Inn Alachua

2.0 star property
Alachua
4.8 out of 10, (595)
"Staff was helpful and so courteous.."
United States
Christian
The price is ₩84,398
₩94,947 total
includes taxes & fees
Nov 24 - Nov 25
Americas Best Value Inn Alachua
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

2.5 star property
Alachua
9.4 out of 10, Exceptional, (466)
"Nice room only there for one night"
United States
Laryssa
The price is ₩149,451
₩168,133 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn & Suites Alachua I-75
Exterior
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
Lake City
8.8 out of 10, Excellent, (1013)
"Excellent hotel. Spacious rooms, comfortable bed, great breakfast and friendly staff. Directly off I-75 for easy on and off. "
United States
Lisa
The price is ₩130,035
₩146,289 total
includes taxes & fees
Dec 8 - Dec 9
La Quinta Inn & Suite by Wyndham Lake City
Double Room, Non Smoking | Laptop workspace, free WiFi
High Springs Country Inn

High Springs Country Inn

2.0 star property
High Springs
8.6 out of 10, Excellent, (13)
"Great remodel of a retro motel."
United States
Kathleen
The price is ₩115,177
₩129,574 total
includes taxes & fees
Nov 24 - Nov 25
High Springs Country Inn
Lobby
Best Western Plus Lake City

Best Western Plus Lake City

2.5 star property
Lake City
9.2 out of 10, Wonderful, (1007)
"It was perfect, we got in super late an was met with a quick check in an a great breakfast the next day"
United States
Aurora
The price is ₩119,303
₩134,215 total
includes taxes & fees
Dec 1 - Dec 2
Best Western Plus Lake City
Property amenity
Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

3.0 star property
Lake City
9.6 out of 10, Exceptional, (170)
"Nice place for a weekend trip to the springs close by.Would definitely stay here again."
United States
Mary
The price is ₩157,395
₩177,069 total
includes taxes & fees
Dec 14 - Dec 15
Courtyard By Marriott Lake City
Lobby
Comfort Suites Lake City

Comfort Suites Lake City

2.5 star property
Lake City
9.6 out of 10, Exceptional, (1003)
"We love to stop here when traveling to Orlando"
United States
Bridget
The price is ₩148,790
₩167,389 total
includes taxes & fees
Dec 14 - Dec 15
Comfort Suites Lake City
Standard Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee

2.5 star property
Live Oak
7.2 out of 10, Good, (604)
"Clean rooms, very friendly staff"
United States
Kristin L
The price is ₩100,027
₩110,029 total
includes taxes & fees
Dec 15 - Dec 16
Quality Inn White Springs Suwanee
Exterior
Tru by Hilton Lake City

Tru by Hilton Lake City

2.5 star property
Lake City
9.2 out of 10, Wonderful, (1009)
"Clean room, easy check in and out, staff if very friendly and helpful"
United States
Row
The price is ₩145,627
₩163,838 total
includes taxes & fees
Nov 23 - Nov 24
Tru by Hilton Lake City
Outdoor pool, sun loungers
Quality Inn Lake City

Quality Inn Lake City

2.5 star property
Lake City
7.8 out of 10, Good, (946)
"Very nice place, would definitely stay there again!"
United States
Gerald
The price is ₩98,776
₩111,124 total
includes taxes & fees
Dec 22 - Dec 23
Quality Inn Lake City
Individually decorated, desk, laptop workspace, iron/ironing board
Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10

2.0 star property
Lake City
6.8 out of 10, (1002)
"Was quite and clean, a little dated but it was a good place to sleep they are pet friendly "
United States
William
The price is ₩94,264
₩106,047 total
includes taxes & fees
Nov 23 - Nov 24
Days Inn by Wyndham Lake City I-10
Lobby
Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

2.5 star property
Lake City
9.0 out of 10, Wonderful, (154)
"Clean property and nice staff"
United States
Thomas
The price is ₩144,156
₩162,176 total
includes taxes & fees
Dec 21 - Dec 22
Fairfield Inn & Suites Lake City
Outdoor pool
Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75

2.5 star property
Lake City
5.0 out of 10, (1001)
"Just a perfect place to take a break while traveling. Clean,comfortable and a great staff. "
United States
Cris
The price is ₩85,023
₩95,651 total
includes taxes & fees
Dec 19 - Dec 20
Baymont by Wyndham Lake City I-75
Standard Cabin, 1 Queen Bed | Exterior
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy

2.0 star property
High Springs
9.8 out of 10, Exceptional, (139)
"Amazing getaway ,, I love the amenities and the firewood and everything was amazing great service perfect escape from reality."
United States
Emperesse
The price is ₩175,047
₩257,275 total
includes taxes & fees
Dec 8 - Dec 9
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
Lobby
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

2.0 star property
Lake City
8.4 out of 10, Very Good, (45)
"Great little motel with extremely nice staff. "
United States
Georgiy
The price is ₩76,770
₩86,361 total
includes taxes & fees
Nov 30 - Dec 1
Motel 6 – Lake City, Fl – Medical Center
Lobby
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

2.5 star property
Lake City
9.4 out of 10, Exceptional, (1001)
"It was a great stay "
United States
Miranda
The price is ₩133,148
₩149,792 total
includes taxes & fees
Dec 7 - Dec 8
Hampton Inn & Suites Lake City
BBQ/picnic area
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

2.0 star property
Lake City
8.8 out of 10, Excellent, (1004)
"Great value, super polite staff, and clean, comfortable rooms"
United States
chelsea
The price is ₩105,028
₩118,156 total
includes taxes & fees
Nov 23 - Nov 24
Americas Best Value Inn Lake City
Reception
BlueGem Motel

BlueGem Motel

2.0 star property
High Springs
9.2 out of 10, Wonderful, (383)
"Great place to stay."
United States
Wesley
The price is ₩147,628
₩166,082 total
includes taxes & fees
Nov 23 - Nov 24
BlueGem Motel
Pillowtop beds, in-room safe, desk, blackout drapes
Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75

2.0 star property
Lake City
7.4 out of 10, Good, (1001)
"We stay at this motel several times a year. It is always clean, the staff is always friendly and welcoming. We wouldn’t stay anywhere else."
United States
Troy
The price is ₩98,776
₩111,124 total
includes taxes & fees
Dec 21 - Dec 22
Days Inn by Wyndham Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

10/10 Excellent
"Nice place to stay one night"
ROBIN 1-night trip
Posted 1 day ago
Courtyard By Marriott Lake City

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
Where can I learn more about changing or cancelling my trip to O Brien?
To access more information about picking new dates or cancelling your trip to O Brien, click here.
Where is the best hotel to stay near Ichetucknee Springs State Park?
Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.
What are some accommodations with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Provides buffet, an outdoor pool, and complimentary wired internet access. La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
What's the best hotel for staying near Gainesville Regional Airport (GNV)?
Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 10 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Lafayette Blue Springs State Park and Lake City Mall in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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