Top Mission Bay Hotels

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most.

A plaza with a traditional building, benches, and a large tree.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

See properties

A beach with surfers and swimmers during sunset.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

See properties

A roller coaster under construction with scaffolding and a ticket booth in the foreground.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

See properties

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

See properties

A beach with palm trees, a hotel, and people enjoying the sand and water.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

See properties

Top Mission Bay Hotel Reviews

The Sofia Hotel

10/10 Excellent

"My girlfriends and I stayed here over the weekend for my Bachelorette party. It well exceeded all my expectations. The staff was very friendly and helpful, the property was very well maintained and clean! The room itself was spotless and beautiful, not to mention the cool high tech gadgets used in the rooms to operate the lights, AC, and privacy sign. The one downfall was that the AC was not super effective and did get a bit stuffy in the room, but it's understandable because it is an older building but hopefully it's something they can look into updating soon. The beds were SO comfy and clean, we slept like babies! Will definitely be gong back and would recommend this hotel to anyone!!"

Omni San Diego Hotel at the Ballpark

8/10 Good

"We had a wonderful stay at this hotel! The check-in process was very smooth, and the front desk staff were consistently kind, welcoming, and helpful throughout our stay. Our room was very spacious, exceptionally clean, and comfortable. The property itself is very well maintained and gives the impression of being newer, even if it may not be. We also really enjoyed the included breakfast—it was a great perk and had a very nice selection. The only area where we felt the experience could have been better was the pool service. One of the ladies working there was extremely kind and attentive, but another staff member seemed to be having a difficult day and unfortunately did not acknowledge us or check in on us at all. Even a quick greeting or letting us know they would be with us shortly would have made a difference. We tried not to let it affect our experience, but it did make the pool service feel a little off. He seemed to only stock the wines but I could hear him complaining throughout his shift. The plastic wine cups were also not clean. The worker had mentioned that all of them look like that, but I rubbed it off and they were just dried old watermarks. Overall, though, we really enjoyed our stay and would definitely recommend this hotel. The friendly front desk staff, spacious and clean rooms, beautiful and well-maintained property, and included breakfast made it a great experience overall. We would happily stay here again!"

Frequently asked questions

What is Mission Bay like?

You'll be sure to have fun visiting San Diego's Mission Bay neighborhood. Looking for sights you might find in a travel guide about Mission Bay? Consider a visit to Mission Bay while you're in the neighborhood.

What's a favorite hotel to stay in Mission Bay?

Based on our traveler data, Paradise Point Resort & Spa is one of the top choices for your stay in Mission Bay. This resort is a short 1-minute walk from Mission Bay, and it offers a marina and 5 outdoor pools. Other good options for your stay in the neighborhood include The Dana on Mission Bay and Hyatt Regency Mission Bay Spa and Marina.

How many hotels should I expect to find in Mission Bay?

If you're searching for places to stay in San Diego, Expedia has something to meet your needs with 46 Mission Bay hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?

Yes, you'll find most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to view the best options available in Mission Bay.

Where can I learn more about changing or cancelling my trip to Mission Bay?

To find more details about updating your trip to Mission Bay or cancelling it, head over to our customer service page.

What is there to do around this San Diego neighborhood?

Dip your toes in the water at Mission and Pacific Beaches or Ski Beach while you're in Mission Bay. You could also plan a visit to Mission Bay or The Dana On Mission Bay, BW Premier Collection while you're in the neighborhood. Don't miss favorite places to visit in the surrounding area, such as Mission Beach, Marine Corps Recruit Depot, and Hotel Circle. When you're sightseeing in San Diego, Crown Point Shores and North Cove Beach are also worth a stop.

Find hotels in Mission Bay, San Diego

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Mission Bay hotels

1. The Dana on Mission Bay

2. San Diego Mission Bay Resort

3. Paradise Point Resort & Spa

4. Hyatt Regency Mission Bay Spa and Marina

5. Hampton Inn & Suites by Hilton San Diego SeaWorld Near Old Town

6. Old Town Inn

7. Comfort Inn Sea World Area

8. Wyndham Garden San Diego Near SeaWorld

9. Hampton Inn & Suites San Diego Airport Liberty Station

10. Holiday Inn Express San Diego - SeaWorld Area by IHG

11. Best Western Plus Marina Gateway Hotel

12. Kings Inn San Diego

13. GreenTree Inn San Diego Mission Bay

14. Heritage Inn San Diego

15. Sheraton San Diego Resort

16. Hilton Garden Inn San Diego Old Town/SeaWorld Area

17. Comfort Inn San Diego Old Town

18. Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

19. Best Western Seven Seas

20. Handlery Hotel

Where to stay in Mission Bay

Downtown San Diego

Pacific Beach

Mission Beach

Gaslamp Quarter

Ocean Beach

Top Mission Bay Hotel Reviews

The Sofia Hotel

Frequently asked questions