A group of men in red uniforms with gold accents, holding rifles and wearing kilts.

Find Cheap Hotels in Southeast Missouri, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri Cheap Hotels

Tonight
Oct 22 - Oct 23
Tomorrow
Oct 23 - Oct 24
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Southeast Missouri cheap hotels

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

1. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Troy
₩95,506
₩107,744 total
includes taxes & fees
Nov 1 - Nov 2
Pear Tree Inn Cape Girardeau West
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A motel with a prominent '66' sign, large windows, and a flat roof.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.

2. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Cindy
₩94,324
₩105,618 total
includes taxes & fees
Nov 5 - Nov 6
Motel 6 Poplar Bluff, MO
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.
A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.
A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.

3. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
United States
Craig
₩92,189
₩105,073 total
includes taxes & fees
Nov 2 - Nov 3
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.
A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.
A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.
A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

4. Town House Inn

Town House Inn
Jackson
United States
Jennifer
₩94,564
₩102,342 total
includes taxes & fees
Oct 26 - Oct 27
Town House Inn
A hotel room with a brick exterior, a sliding glass door, a window with a view, and a built-in heater.
A parking lot with a sign for 'Rosener's Inn' and a flagpole with an American flag.
A motel sign with "ROSENER'S INN" written on it.
A bathroom with a toilet, bathtub, and sink.

5. Rosener's Inn and banquet center

Rosener's Inn and banquet center
Park Hills
United States
Jose
₩94,314
₩103,604 total
includes taxes & fees
Oct 31 - Nov 1
Rosener's Inn and banquet center
A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.
Front of property
A calm lake with a wooden dock and a forested island in the distance.
A wooden deck with a railing leading to a building with a metal roof and a brown door.

6. Lake Wappapello

Lake Wappapello
Williamsville
United States
Tonya
₩119,398
₩125,936 total
includes taxes & fees
Oct 25 - Oct 26
Lake Wappapello
A hotel room with two beds, a desk, a chair, a lamp, and a painting on the wall.
A reception area with a wooden reception desk, a sign indicating complimentary breakfast availability, and a ceiling fan.
A spacious indoor area with a reception desk, a dining table with chairs, a ceiling fan, and a television mounted on the wall.
A white bathtub with chrome fixtures and a shower curtain.

7. Americas Best Value Inn Sullivan

Americas Best Value Inn Sullivan
Sullivan
United States
Emil
₩92,852
₩101,183 total
includes taxes & fees
Oct 23 - Oct 24
Americas Best Value Inn Sullivan
A hotel room with a bed, two bedside tables, a ceiling fan, and two wall-mounted lamps.
A small kitchenette with a microwave, a sink, and a bench.
A reception area with a dark wooden counter, a water dispenser, potted plants, and a large window with an eagle mural.
A modern bathroom with a toilet, sink, and towel hooks.

8. Motel 6 Sullivan, MO

Motel 6 Sullivan, MO
Sullivan
United States
Dane
₩92,852
₩101,186 total
includes taxes & fees
Oct 25 - Oct 26
Motel 6 Sullivan, MO
A hotel room with two beds, a desk, a chair, a dresser, and a TV.
A swimming pool with clear blue water, surrounded by lounge chairs and a fenced area.
A dining area with wooden tables and chairs, a kitchen area with a coffee machine, and a brick wall.
A modern building with a brick facade and a green roof.

9. Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
Fenton
United States
William
₩104,859
₩121,101 total
includes taxes & fees
Oct 25 - Oct 26
Wingate by Wyndham St. Louis/Fenton Route 66
View all properties

Top Southeast Missouri Hotel Reviews

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

10/10 Excellent
"Super clean and helpful friendly staff. Rooms are a bit small but still nice and modern. Only downside was no breakfast."
Sarah 1-night trip
Posted 2 days ago
Motel 6 Poplar Bluff, MO
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Stayed here for a long weekend motorcycle trip. The hotel is conveniently located near many shopping and dining choices. The room was basic but clean and quiet, and lots of channels on the tv! Staff were super friendly and helpful. I will definitely stay here again the next time I am in Cape Girardeau."
Robert 3-night trip
Posted 3 days ago
Pear Tree Inn Cape Girardeau West
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"We have stayed here a number of times over 20 years. It’s always clean and well maintained. Breakfast is very good. Staff is always friendly and helpful."
John 3-night trip
Posted 9 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"good, clean, affordable :)"
Nicholas 1-night trip
Posted 9 days ago
Super 8 by Wyndham Sikeston/Miner Area

Explore a world of travel with Expedia