Southeast Jacksonville Adventure Vacations
Book a Adventure Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ₩1,660,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Adventure Southeast Jacksonville Hotels
Delta Hotels by Marriott™ Jacksonville Deerwood
4700 Salisbury Rd Jacksonville FL
- 10 min drive from Mayo Clinic Florida
Book a stay at this business-friendly hotel in Jacksonville. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful ...
8.6/10 Excellent! (743 reviews)
"all good with the stay....."
Reviewed on Oct 15, 2026
Residence Inn by Marriott Jacksonville Butler Boulevard
10551 Deerwood Park Blvd Jacksonville FL
- 7 min drive from Mayo Clinic Florida
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,000 reviews)
"Clean and spacious rooms. The AC definitely kept the room cold but it felt a bit wet and soggy in there too. We booked the hotel for the hot tub and it never got warm. Good breakfast."
Reviewed on Oct 15, 2026
Marriott Jacksonville
4670 Salisbury Rd Jacksonville FL
- 10 min drive from Mayo Clinic Florida
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free parking, breakfast (surcharge), and room service. Our guests praise the helpful staff ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
