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Top Adventure Southeast Jacksonville Hotels

Delta Hotels by Marriott™ Jacksonville Deerwood

4700 Salisbury Rd Jacksonville FL

10 min drive from Mayo Clinic Florida

Book a stay at this business-friendly hotel in Jacksonville. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful ...

8.6/10 Excellent! (756 reviews)

"Clean room and the staff"

Reviewed on Nov 2, 2026

Marriott Jacksonville

4670 Salisbury Rd Jacksonville FL

10 min drive from Mayo Clinic Florida

Book a stay at this business-friendly hotel in Jacksonville. Enjoy free parking, breakfast (surcharge), and room service. Our guests praise the helpful staff ...

Wyndham Garden Jacksonville

4660 Salisbury Road Jacksonville FL

10 min drive from Mayo Clinic Florida

Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...

8/10 Very Good! (2,132 reviews)

"checked into the hotel on October 27 at 9:30 PM and stayed for one night. I checked out at 9:00 AM on October 28. The price on the booking app was $79, but I was charged $129."

Reviewed on Nov 3, 2026

See all 598 properties in Southeast Jacksonville

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.