Southwest Ohio Luxury Vacations

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Top Luxury Southwest Ohio Hotels

21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

609 Walnut St Cincinnati OH
  • 8 min walk from Great American Ball Park
21c Museum Hotel Cincinnati is one of the Cincinnati luxury 4.5-star boutique properties where you can treat yourself to Champagne service, Egyptian cotton sheets, ...
8.6/10 Excellent! (1,021 reviews)
"Overall nice hotel in a convenient location downtown Cincinnati. Parking off site down the road could get expensive but I was here for one night. Only thing I could think that others could find inconvenient is there’s no sort of fridge in the room."

Reviewed on Sep 15, 2026

21c Museum Hotel Cincinnati
The Cincinnatian Hotel Curio Collection by Hilton

The Cincinnatian Hotel Curio Collection by Hilton

601 Vine Street Cincinnati OH
  • 8 min walk from Great American Ball Park
Be treated to luxurious accommodations at The Cincinnatian Hotel Curio Collection by Hilton, where you can enjoy amenities like plush bedding, designer toiletries, ...
The Cincinnatian Hotel Curio Collection by Hilton
Hotel Covington Cincinnati Riverfront

Hotel Covington Cincinnati Riverfront

638 Madison Ave Covington KY
  • 19 min walk from Great American Ball Park
Discover luxurious lodging at Hotel Covington Cincinnati Riverfront, where you can enjoy amenities like plush bedding, designer toiletries, and more. Deluxe ...
Hotel Covington Cincinnati Riverfront
See all 3,409 properties in Southwest Ohio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.