
Popular airlines from Des Moines International Airport (DSM) to Chicago O'Hare Intl. Airport (ORD)
- American Airlines
American Airlines
- Delta
Delta
- United
United
- Southwest Airlines
Southwest Airlines
- Frontier Airlines
Frontier Airlines
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 40% on select hotels after you book a flight*
Find the cheapest month to fly from Des Moines (DSM) to Chicago (ORD)
September is typically the cheapest month to fly
Origin airport | Des Moines Intl. |
|---|---|
Destination airport | O'Hare Intl. |
Distance | 476 km |
Average flight time | 1 hour 36 mins |
Des Moines to Chicago Flights
Sometimes you just need to get out of town or maybe you’re looking for a change of scenery. Regardless of the reason, a flight from Des Moines to Chicago will do just the trick! Go on, plan to see all the famous landmarks and eat your weight in the local cuisine. Your trip is beckoning, so answer the call by packing your suitcase and filling your travel itinerary with exploring Chicago.
Whether you’re flying for business or jet-setting on your personal time, you’ve come to the right place. Here at Expedia.com, we’ll pair you up with DSM to ORD flights that won’t make your bank account wince. Ready to temporarily leave behind Des Moines for new horizons? Browse through our cheap airfare, and filter by flight times and dates until you find just what you had in mind. From flights without layovers to ones that arrive early in the morning, you’ll come across plane tickets that suit your travel preferences. You can even bundle your flight to ORD with hotels and car rentals to score even bigger savings.
All set to hit the clouds? Book your travel arrangements with us today and have left-over money to put toward your travel outings and adventures.
Frequently asked questions
Explore a world of travel with Expedia
- Trending Routes
- Top Flights Destinations
- Airlines Operating
- Flights From Other Airports
- Expedia's Latest Trends
Top Routes from Des Moines
Top Routes to Chicago
- Newark Liberty Intl. Airport to Chicago (EWR - ORD)
- Los Angeles to Chicago (LAX - ORD)
- Kuala Lumpur to Chicago (KUL - ORD)
- Grand Rapids to Chicago (GRR - ORD)
- New York to Chicago (LGA - ORD)
- Manila to Chicago (MNL - ORD)
- Seoul to Chicago (GMP - ORD)
- New York to Chicago (JFK - ORD)
- Seattle to Chicago (SEA - ORD)
- Busan to Chicago (PUS - ORD)
- Vancouver to Chicago (YVR - ORD)
- Dallas to Chicago (DFW - ORD)
Top Flight Destinations
- Flights to New York
- Flights to Las Vegas
- Flights to Orlando
- Flights to Chicago
- Flights to Miami
- Flights to Los Angeles
- Flights to San Diego
- Flights to San Francisco
- Flights to Fort Lauderdale
- Flights to Key West
- Flights to Atlanta
- Flights to Honolulu
- Flights to New Orleans
- Flights to Gatlinburg
- Flights to San Antonio
- Flights to Austin
- Flights to Nashville
- Flights to Boston
- Flights to Anaheim
- Flights to Dallas
Expedia's Latest Trends
- Econo Lodge South Holland - Chicago Southland
- Hotels near Millennium Park
- Congress Plaza Hotel
- Mitsui Garden Hotel Ginza Premier
- Arlo Chicago
- Urbanstay Myeongdong
- Freehand Chicago
- Hyatt Regency Chicago
- Hilton Chicago O'Hare Airport
- InterContinental Chicago Magnificent Mile by IHG
- Hotels in Downtown Chicago
- The Quarter Ari by UHG
- Sheraton Grand Chicago Riverwalk
- Park Hyatt Kyoto