Southeast Missouri Adventure Vacations
Book a Adventure Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ₩1,660,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Adventure Southeast Missouri Hotels
Hampton Inn Farmington
850 Valley Creek Dr Farmington MO
- 2 hours drive from Mark Twain National Forest
Stay at this hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Crown Pointe Lodge, BW Signature Collection
4245 Hunt Rd Farmington MO
- 2 hours drive from Mark Twain National Forest
Book a stay at this golf hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (683 reviews)
"Arrived at 10 PM it was nice to have a helpful front desk person. Room was clean. However, the l ceiling light just inside the front door is a CFL and very dim the first 10 minutes. Same for the bathroom sconces on each side of the mirror. The light bulbs in two light fixtures between the beds, we’re ..."
Reviewed on Oct 1, 2026
Echo Bluff State Park
34489 Echo Bluff Dr Eminence MO
- 43 min drive from Mark Twain National Forest
Book a stay at this business-friendly hotel in Eminence. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Echo Bluff State Park and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
