A coastal landscape with clear turquoise waters, a long bridge, and a small island with buildings.

Lower Florida Keys 5 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Lower Florida Keys 5 Star Hotels

This weekend
Jul 31 - Aug 2
Next weekend
Aug 7 - Aug 9
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lower Florida Keys.
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL
The price is ₩220,097 per night from Aug 24 to Aug 25
₩220,097
₩353,107 total
Aug 24 - Aug 25
includes taxes & fees
8.8/10 Excellent! (3,495 reviews)
Still don't see what you're looking for?
See all properties in Lower Florida Keys.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Lower Florida Keys

Venture to popular sights like Florida Keys Beaches and Duval Street as you discover Lower Florida Keys.

See all hotels in Lower Florida Keys
A coastal landscape with clear turquoise waters, a long bridge, and a small island with buildings.

Top Lower Florida Keys Hotel Reviews