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Check prices for these dates

This weekend
Jul 10 - Jul 12
Next weekend
Jul 17 - Jul 19

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Our top choices for Effingham hotels

Breakfast included
Exterior

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (614 reviews)
"Clean , comfortable bed , good breakfast and right off the highway"
United States
Diana
The price is ā‚©166,349
ā‚©181,321 total
includes taxes & fees
Aug 2 - Aug 3
Holiday Inn Express & Suites Latta by IHG
Lobby

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,686 reviews)
"This is a hidden gem long I-95! Donā€™t be fooled by the dated exterior, the rooms are clean and updated with new flooring, shower and fixtures. A great value at an affordable price!"
United States
Dave
The price is ā‚©94,428
ā‚©105,758 total
includes taxes & fees
Jul 12 - Jul 13
Howard Johnson by Wyndham Florence
Lobby

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,335 reviews)
"Location, clean and very pleasant staff - fair pricing too"
United States
Marilyn
The price is ā‚©126,804
ā‚©142,022 total
includes taxes & fees
Jul 19 - Jul 20
Park Inn by Radisson Florence, SC
Exterior

Best Western Executive Inn

Best Western Executive Inn
2.5 star property
Latta
8.2 out of 10, Very Good, (1,003 reviews)
"Basic Hotel everything was great"
United States
Rudy
The price is ā‚©165,639
ā‚©180,547 total
includes taxes & fees
Aug 11 - Aug 12
Best Western Executive Inn
Exterior

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.6 out of 10, Good, (410 reviews)
"The hotel is close to my relatives house"
United States
Shawnta
The price is ā‚©130,581
ā‚©142,333 total
includes taxes & fees
Jul 31 - Aug 1
Quality Inn Mullins - Marion
Desk, iron/ironing board, free WiFi, bed sheets

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.2 out of 10, Good, (1,014 reviews)
"Good overnight stay for a good price."
United States
Marie
The price is ā‚©95,927
ā‚©107,438 total
includes taxes & fees
Jul 12 - Jul 13
Days Inn by Wyndham Florence Near Civic Center
Lobby sitting area

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.4 out of 10, Very Good, (205 reviews)
"Very clean and very friendly staff. Comfortable rooms, lovely pool"
United States
Kaitlyn
The price is ā‚©121,707
ā‚©142,232 total
includes taxes & fees
Jul 19 - Jul 20
Spark by Hilton Florence North I-95, SC
View from property

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.0 out of 10, Wonderful, (647 reviews)
"The room was clean and the breakfast was delicious!"
United States
Itid
The price is ā‚©189,831
ā‚©212,610 total
includes taxes & fees
Jul 19 - Jul 20
Fairfield Inn & Suites by Marriott Florence I-20
Terrace/patio

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,015 reviews)
"This is Hotel has breath taking amenities. The staff are attentive, the breakfast buffet is delicious. Great room prices, I will book again."
United States
Salma
The price is ā‚©170,870
ā‚©191,374 total
includes taxes & fees
Aug 3 - Aug 4
Hyatt Place Florence Downtown
Room, 1 Queen Bed, Accessible, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence
2.0 star property
Florence
6.8 out of 10, (1,002 reviews)
"Room was clean, staff was respectful, great stay, thank you"
United States
Cosmin
The price is ā‚©81,566
ā‚©91,354 total
includes taxes & fees
Jul 12 - Jul 13
Microtel Inn & Suites by Wyndham Florence
Exterior

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,008 reviews)
"Great stay. Clean room, great breakfast"
United States
Tim
The price is ā‚©166,349
ā‚©192,269 total
includes taxes & fees
Aug 2 - Aug 3
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Lobby

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,330 reviews)
"Clean room and breakfast was great"
United States
Dana
The price is ā‚©156,961
ā‚©175,796 total
includes taxes & fees
Jul 19 - Jul 20
Comfort Inn & Suites Florence Center Area
Lobby

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,564 reviews)
"Very clean, everyone was very courteous area seemed very safe would book again"
United States
Ray
The price is ā‚©140,021
ā‚©156,818 total
includes taxes & fees
Jul 19 - Jul 20
La Quinta Inn & Suites by Wyndham Florence
Front of property

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.8 out of 10, Good, (1,003 reviews)
"For a roadside hotel it felt clean and pleasant. "
United States
Marianna
The price is ā‚©106,719
ā‚©119,524 total
includes taxes & fees
Jul 19 - Jul 20
Best Western Inn
Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, iron/ironing board, free cribs/infant beds

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.6 out of 10, Excellent, (240 reviews)
"The room was clean the staff was friendly and the pool was great"
United States
Kezia
The price is ā‚©130,505
ā‚©146,166 total
includes taxes & fees
Jul 12 - Jul 13
Quality Inn & Suites Florence Civic Center
Exterior

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (1,006 reviews)
"Great stay"
United States
Odaliz
The price is ā‚©188,856
ā‚©211,520 total
includes taxes & fees
Jul 19 - Jul 20
Staybridge Suites Florence - Civic Center by IHG
Restaurant

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (949 reviews)
"Pleasant stay, clean rooms and facilities, awesome fresh breakfast all 3 days!! Highly recommend this hotel for your stay in Florence, Darlington areas."
United States
GILL
The price is ā‚©164,695
ā‚©184,459 total
includes taxes & fees
Aug 3 - Aug 4
Hampton Inn & Suites Florence-North-I-95
Terrace/patio

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.6 out of 10, Excellent, (1,007 reviews)
"Great amenities the lobby was huge and really nice."
United States
Elizabeth
The price is ā‚©146,409
ā‚©169,238 total
includes taxes & fees
Aug 11 - Aug 12
Tru by Hilton Florence I-95
Lobby

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.2 out of 10, Very Good, (1,006 reviews)
"The breakfast was great and the rooms were super comfortable "
United States
Jessica
The price is ā‚©123,222
ā‚©158,842 total
includes taxes & fees
Aug 10 - Aug 11
Comfort Suites Florence I-95
Exterior

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.6 out of 10, (1,004 reviews)
"The shower didnā€™t have any water so it didnā€™t work The swimming never opened up"
United States
Tammy
The price is ā‚©80,264
ā‚©89,897 total
includes taxes & fees
Aug 3 - Aug 4
Days Inn by Wyndham Florence/I-95 North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Effingham Hotel Reviews

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

10/10 Excellent
"All was excellent. I definitely will stay again on my next trip"
Orlando 1-night trip
Posted 1 hour ago
Comfort Inn & Suites Florence Center Area

More cheap stays in Effingham

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North

2111 West Lucas St/I-95 Florence SC
The price is ā‚©80,264 per night from Aug 3 to Aug 4
ā‚©80,264
ā‚©89,897 total
Aug 3 - Aug 4
includes taxes & fees
6.6/10 (1,004 reviews)

Frequently asked questions

Where is the best place to stay in Effingham?
Park Inn by Radisson Florence, SC, located 12.2 mi (19.6 km) from the heart of Effingham, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Howard Johnson by Wyndham Florence and Comfort Inn & Suites Florence Center Area. See all available top hotels, or vacation rentals in Effingham.
If I need to cancel my hotel reservation in Effingham, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Effingham.
Where can I learn more about changing or cancelling my trip to Effingham?
For more details about changing or cancelling your trip to Effingham, click here.
How is it to stay in Effingham?
Travelers to Effingham will find plenty to explore and enjoy. There are 153 hotels and other accommodations in the surrounding area. Find out more about Effingham.
What should I see while I'm in Effingham?
A favorite place to visit is Lynches River State Park. You'll also find Florence National Cemetery and Florence Museum in the area. Check out what more to see and do in Expedia's Effingham guide.
What's the weather like in Effingham?
The hottest months are usually July and August with an average temp of 78Ā°F, while the coldest months are January and February with an average of 50Ā°F. Average annual precipitation for Effingham is 54 inches.