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Our top choices for Mayo Clinic hotels

Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.6 out of 10, Exceptional, (558 reviews)
"Great hotel. Best in the city by far. "
Canada
jonathan
The price is ₩247,569
₩285,015 total
includes taxes & fees
Mar 6 - Mar 7
Hilton Rochester Mayo Clinic Area
Pub

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park, 0.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (491 reviews)
"Staff was very helpful. Room was spacious and beds were very comfortable. "
United States
Lisa
The price is ₩184,415
₩212,307 total
includes taxes & fees
Feb 13 - Feb 14
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Lobby

The Berkman

The Berkman
3.0 star property
Folwell, 1.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (382 reviews)
"Everything was excellent, second time staying there. "
United States
Carolyn
The price is ₩251,574
₩292,514 total
includes taxes & fees
Feb 4 - Feb 5
The Berkman
View from property

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park, 1.8 km from Mayo Clinic
9.6 out of 10, Exceptional, (686 reviews)
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is ₩141,567
₩162,979 total
includes taxes & fees
Mar 6 - Mar 7
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Courtyard

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (989 reviews)
"Great hotel!"
United States
Narcedalia
The price is ₩146,879
₩171,998 total
includes taxes & fees
Feb 6 - Feb 7
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Terrace/patio

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
2.6 km from Mayo Clinic
9.6 out of 10, Exceptional, (908 reviews)
"Staff, room and breakfast were wonderful!"
United States
DeLaine
The price is ₩177,416
₩204,251 total
includes taxes & fees
Feb 12 - Feb 13
Home2 Suites by Hilton Rochester Mayo Clinic Area
Indoor pool

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
2.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (262 reviews)
"Staff was great and helpful, lovely room!, quiet area, restaurants nearby"
United States
Ann Marie
The price is ₩191,676
₩220,666 total
includes taxes & fees
Feb 7 - Feb 8
Residence Inn by Marriott Rochester Mayo Clinic Area South
Lobby

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (436 reviews)
"Great room, location, very clean "
United States
John
The price is ₩183,907
₩214,633 total
includes taxes & fees
Feb 6 - Feb 7
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Front of property - evening/night

The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel
4.0 star property
Downtown Rochester, 0.1 km from Mayo Clinic
9.4 out of 10, Exceptional, (96 reviews)
"Excellent accommodations, amazing staff"
United States
Shannon
The price is ₩567,230
₩653,023 total
includes taxes & fees
Feb 5 - Feb 6
The Towers At Kahler Grand Hotel
Two-Bedroom Apartment - Mobility Accessible/Non-Smoking | In-room safe, individually furnished, desk, laptop workspace

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (170 reviews)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is ₩247,000
₩284,360 total
includes taxes & fees
Feb 21 - Feb 22
Broadway Plaza, Trademark Collection by Wyndham
Exterior

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (781 reviews)
"Room was clean and the housekeeping person very helpful and courteous "
United States
Dawn
The price is ₩150,234
₩172,956 total
includes taxes & fees
Feb 13 - Feb 14
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Terrace/patio

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,004 reviews)
"Great place to stay"
United States
Cristopher
The price is ₩201,841
₩232,371 total
includes taxes & fees
Feb 7 - Feb 8
Hyatt House Rochester/Mayo Clinic Area
Terrace/patio

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (493 reviews)
"We have stayed here often in the past year. The staff is so kind. Rooms are extremely comfortable and clean. Breakfast is excellent. "
United States
Annie
The price is ₩153,602
₩176,834 total
includes taxes & fees
Feb 20 - Feb 21
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Lobby sitting area

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (1,000 reviews)
"Clean and comfortable Close to the hospital for convenience "
United States
Dianne
The price is ₩163,360
₩188,060 total
includes taxes & fees
Feb 4 - Feb 5
Brentwood Inn & Suites
Front of property

Aspen Suites

Aspen Suites
3.0 star property
1.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (715 reviews)
"Very clean and nice staff"
United States
Kirk
Aspen Suites
Exterior

Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
2.6 km from Mayo Clinic
9.2 out of 10, Wonderful, (461 reviews)
"The staff checking in and out were helpful and friendly. The room was clean, comfortable, and quiet. "
United States
Allison
The price is ₩135,044
₩155,469 total
includes taxes & fees
Feb 8 - Feb 9
Candlewood Suites Rochester Mayo Clinic Area by IHG
Exterior

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 0.4 km from Mayo Clinic
8.8 out of 10, Excellent, (926 reviews)
"Great stay as always! "
United States
Misty
The price is ₩130,688
₩150,465 total
includes taxes & fees
Feb 21 - Feb 22
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Breakfast served

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (871 reviews)
"Very convenient and clean hotel "
United States
Kirsten
The price is ₩154,611
₩177,995 total
includes taxes & fees
Feb 13 - Feb 14
Hilton Garden Inn Rochester Downtown, MN
Reception

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
2.9 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,001 reviews)
"Great place"
United States
Randall
The price is ₩113,621
₩130,806 total
includes taxes & fees
Mar 6 - Mar 7
Hampton Inn Rochester-South
Free daily full breakfast

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3.1 km from Mayo Clinic
9.0 out of 10, Wonderful, (930 reviews)
"Very clean and staff was friendly. "
United States
Robert
The price is ₩97,566
₩112,322 total
includes taxes & fees
Mar 1 - Mar 2
Econo Lodge Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent
"Front desk and cleaning staff are so kind and helpful! Rooms are clean and up to date! Comfortable beds and atmosphere! Definitely stay again."
Joel 1-night trip
Posted 3 days ago
AmericInn by Wyndham Rochester Near Mayo Clinic

Hotels near other Mayo Clinic attractions

Soldiers Field Veterans Memorial

4.5/5 (30 reviews)
You can learn about the history of Rochester with a visit to Soldiers Field Veterans Memorial. Attend a sporting event or simply visit the area's shops.
See properties

Plummer Building

You can find out about the history of Rochester when you stop by Plummer Building.
See properties

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 158 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 158 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?
For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.