A historic building with a prominent tower, two American flags, and a modern glass structure in the foreground.

Find hotels near Mayo Clinic, Rochester from ₩127,248

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic hotels

1. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.6 out of 10, Exceptional, (612 reviews)
"Convenient, short walk to Mayo and two excellent restaurants."
United States
Jerome
The price is ₩262,328
₩302,005 total
includes taxes & fees
Jul 4 - Jul 5
Hilton Rochester Mayo Clinic Area

2. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park, 0.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (538 reviews)
"Great place to stay"
United States
Brian
The price is ₩221,308
₩254,781 total
includes taxes & fees
Jul 4 - Jul 5
TownePlace Suites by Marriott Rochester Mayo Clinic Area

3. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park, 1.8 km from Mayo Clinic
9.6 out of 10, Exceptional, (717 reviews)
"Great location close to St. Marys. The hotel is nice, coffee is good, and overall a nice place to stay."
United States
Brian
The price is ₩182,886
₩210,549 total
includes taxes & fees
Jul 3 - Jul 4
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

4. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (1,003 reviews)
"Great stay"
United States
Samantha
The price is ₩181,349
₩229,545 total
includes taxes & fees
Jul 5 - Jul 6
EVEN Hotel Rochester - Mayo Clinic Area by IHG

5. The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel
4.0 star property
Downtown Rochester, 0.1 km from Mayo Clinic
9.4 out of 10, Exceptional, (110 reviews)
"Impressive customer service, everyone was wonderful! The air conditioner is old though so room felt a little warm and stuffy."
United States
Kim
The price is ₩613,037
₩705,750 total
includes taxes & fees
Jul 15 - Jul 16
The Towers At Kahler Grand Hotel

6. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
2.6 km from Mayo Clinic
9.6 out of 10, Exceptional, (993 reviews)
"Friendly staff , good breakfast, and clean room"
United States
Ali
The price is ₩193,861
₩223,183 total
includes taxes & fees
Jul 4 - Jul 5
Home2 Suites by Hilton Rochester Mayo Clinic Area

7. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (490 reviews)
"Great stay!"
United States
Kristina
The price is ₩189,034
₩220,700 total
includes taxes & fees
Jul 19 - Jul 20
Staybridge Suites Rochester - Mayo Clinic Area by IHG

8. Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
2.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (291 reviews)
"Great stay."
United States
Engen
The price is ₩217,357
₩250,232 total
includes taxes & fees
Jul 5 - Jul 6
Residence Inn by Marriott Rochester Mayo Clinic Area South

9. The Berkman

The Berkman
3.0 star property
Folwell, 1.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (419 reviews)
"Great stay"
United States
Kayla
The price is ₩330,627
₩384,446 total
includes taxes & fees
Jul 6 - Jul 7
The Berkman

10. Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
2.6 km from Mayo Clinic
9.4 out of 10, Exceptional, (501 reviews)
"Friendly staff and clean suite"
United States
Cindy
The price is ₩163,783
₩188,556 total
includes taxes & fees
Jul 4 - Jul 5
Candlewood Suites Rochester Mayo Clinic Area by IHG

11. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,004 reviews)
"Great room and good breakfast!"
United States
Bridgett
The price is ₩259,729
₩299,014 total
includes taxes & fees
Jun 27 - Jun 28
Hyatt House Rochester/Mayo Clinic Area

12. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (518 reviews)
"They had an excellent hot breakfast. Room was clean and well equipped for eating in the room. Staff was very helpful."
United States
Ronald Wayne
The price is ₩196,534
₩226,257 total
includes taxes & fees
Jul 3 - Jul 4
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

13. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (799 reviews)
"The staff here is great Cozy restaurant."
United States
MATTHEW
The price is ₩213,624
₩245,933 total
includes taxes & fees
Jun 27 - Jun 28
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

14. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 0.4 km from Mayo Clinic
8.8 out of 10, Excellent, (1,006 reviews)
"As always it was a wonderful stay!"
United States
Misty
The price is ₩184,423
₩212,317 total
includes taxes & fees
Jun 30 - Jul 1
Hotel Indigo Rochester – Mayo Clinic Area by IHG

15. Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (1,001 reviews)
"very clean and friendly staff"
United States
Ed
The price is ₩152,149
₩175,171 total
includes taxes & fees
Jun 26 - Jun 27
Brentwood Inn & Suites

16. Aspen Suites

Aspen Suites
3.0 star property
1.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (862 reviews)
"Great place to stay near downtown!! Breakfast was good and the hotel room was very clean!"
United States
Rhianon
The price is ₩217,957
₩263,479 total
includes taxes & fees
Jun 28 - Jun 29
Aspen Suites

17. Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (916 reviews)
"Nice hotel near mayo. "
United States
Rob
The price is ₩187,018
₩215,306 total
includes taxes & fees
Jul 12 - Jul 13
Hilton Garden Inn Rochester Downtown, MN

18. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3.1 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice place for the value. I would stay again."
United States
Dominic
The price is ₩110,530
₩127,248 total
includes taxes & fees
Jul 12 - Jul 13
Econo Lodge Mayo Clinic Area

19. Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
2.9 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,013 reviews)
"Great experience, would definitely stay again!!"
United States
Mike
The price is ₩151,089
₩173,940 total
includes taxes & fees
Jul 12 - Jul 13
Hampton Inn Rochester-South

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest, 0.6 km from Mayo Clinic
8.6 out of 10, Excellent, (1,016 reviews)
"Very affordable we were visiting family overall stay was prefect"
United States
James
The price is ₩175,509
₩202,051 total
includes taxes & fees
Jun 28 - Jun 29
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV
Hilton Rochester Mayo Clinic Area
3.5 star property
9.6
Exceptional
612 reviews
View
Pub
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
9.6
Exceptional
538 reviews
View
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
9.6
Exceptional
717 reviews
View
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
9.4
Exceptional
1,003 reviews
View
Front of property - evening/night
The Towers At Kahler Grand Hotel
4.0 star property
9.4
Exceptional
110 reviews
View

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 148 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hyatt House Rochester/Mayo Clinic Area.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 148 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?
For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.