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Our top choices for Mississippi River hotels

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (360 reviews)
"Staff was really nice and helpful."
United States
rhonda
The price is ₩118,682
₩134,749 total
includes taxes & fees
Mar 10 - Mar 11
River's Edge Motel

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (21 reviews)
"Room was spacious and clean. Had a great stay. The restaurant was delicious. "
United States
James
The price is ₩141,854
₩161,057 total
includes taxes & fees
Mar 15 - Mar 16
The Eagles Nest Inn

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (743 reviews)
"Thanks to the staff very help and kind. Very good stay. "
United States
Terry
The price is ₩93,462
₩108,067 total
includes taxes & fees
Mar 11 - Mar 12
Baymont by Wyndham Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,014 reviews)
"Everything was great. Will definitely stay again."
United States
Ethan
The price is ₩104,429
₩119,936 total
includes taxes & fees
Mar 10 - Mar 11
Best Western On The River

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (168 reviews)
"Great place to stay!"
United States
Sandy
The price is ₩211,070
₩293,530 total
includes taxes & fees
Mar 10 - Mar 11
Riverside Inn Hannibal

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,004 reviews)
"It was a good midway stop for us on our way to Memphis."
United States
Joel
The price is ₩162,669
₩188,453 total
includes taxes & fees
Mar 29 - Mar 30
Sleep Inn & Suites Hannibal West

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (25 reviews)
"Nice room. Matched the pictures. Exactly what we were looking for."
United States
John
The price is ₩236,347
₩322,560 total
includes taxes & fees
Mar 10 - Mar 11
Lighthouse Inn & Suites

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (678 reviews)
"Everything was clean and staff was friendly. Just needed some updates. "
United States
Georgia
The price is ₩117,080
₩138,917 total
includes taxes & fees
Mar 29 - Mar 30
Comfort Inn & Suites - Hannibal

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very Good, (39 reviews)
"Great location. Clean rooms, Staff very friendly."
United States
Charles
The price is ₩158,886
₩182,480 total
includes taxes & fees
Mar 10 - Mar 11
Garden House Bed and Breakfast

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,002 reviews)
"Overall, very nice stay"
United States
Cary
The price is ₩81,579
₩93,685 total
includes taxes & fees
Mar 11 - Mar 12
Motel 6 Hannibal, MO

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,001 reviews)
"clean room - soft beds - friendly staff - very welcoming - lobby nice"
United States
Maxine
The price is ₩89,012
₩102,245 total
includes taxes & fees
Mar 22 - Mar 23
Super 8 by Wyndham Hannibal

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very Good, (1,015 reviews)
"Good breakfast selections. Close to a good restaurant. "
United States
Steve
The price is ₩118,831
₩137,667 total
includes taxes & fees
Mar 15 - Mar 16
Quality Inn & Suites Hannibal West

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (225 reviews)
"Convenient stop and very pleasant , clean and friendly atmosphere"
United States
John David
The price is ₩98,655
₩113,304 total
includes taxes & fees
Mar 10 - Mar 11
Days Inn by Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (156 reviews)
"Yes my stay was great"
United States
Aaron
The price is ₩84,561
₩97,794 total
includes taxes & fees
Mar 11 - Mar 12
Howard Johnson BY Wyndham Hannibal

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (520 reviews)
"Really cozy place to stay at!"
United States
Yufei
The price is ₩89,012
₩100,984 total
includes taxes & fees
Mar 10 - Mar 11
Economy Inn Wentzville

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.8 out of 10, (1,006 reviews)
"Clean room very nice staff it’s nice"
United States
Mercedez
The price is ₩93,462
₩107,407 total
includes taxes & fees
Mar 10 - Mar 11
Relax Inn Saint Charles

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (36 reviews)
"I enjoyed it! And the owners were so sweet and understanding. I would absolutely stay there again!"
United States
Evelyn
The price is ₩100,139
₩113,106 total
includes taxes & fees
Mar 10 - Mar 11
LAKEVIEWINN

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (498 reviews)
"Great location for geode hunting. Irish Pub behind the hotel is the best."
United States
Marty
The price is ₩97,468
₩109,173 total
includes taxes & fees
Mar 22 - Mar 23
Baymont by Wyndham Keokuk

Sleep Inn Saint Charles North

Sleep Inn Saint Charles North
2.5 star property
97.1 km from Mississippi River
5.8 out of 10, (523 reviews)
"The staff was very helpful the rooms where nice very affordable clean and very quiet"
United States
Valerie
The price is ₩107,689
₩123,762 total
includes taxes & fees
Apr 5 - Apr 6
Sleep Inn Saint Charles North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,010 reviews)
"Great staff and the place is nice and clean and the breakfast is awesome."
United States
Kerry
The price is ₩107,185
₩131,021 total
includes taxes & fees
Mar 12 - Mar 13
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Pear Tree Inn St. Louis Airport is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. You'll find it 69.9 mi (112.5 km) from Mississippi River. Other good options around the area include Pear Tree Inn St. Louis Near Union Station and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.