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Sep 10 - Sep 11
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Sep 11 - Sep 12
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Sep 11 - Sep 13
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Sep 18 - Sep 20

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Our top choices for Mississippi River hotels

1. River's Edge Motel

River's Edge Motel
13.6 km from Mississippi River
United States
Paul
₩111,220
₩126,282 total
includes taxes & fees
Sep 12 - Sep 13
River's Edge Motel

2. The Eagles Nest Inn

The Eagles Nest Inn
14.2 km from Mississippi River
United States
Gary
₩150,751
₩171,159 total
includes taxes & fees
Sep 12 - Sep 13
The Eagles Nest Inn

3. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
30.3 km from Mississippi River
United States
Patricia
₩148,753
₩173,073 total
includes taxes & fees
Oct 11 - Oct 12
Sleep Inn & Suites Hannibal West

4. Best Western On The River

Best Western On The River
25.3 km from Mississippi River
United States
Mark
₩147,387
₩170,006 total
includes taxes & fees
Sep 13 - Sep 14
Best Western On The River

5. Riverside Inn Hannibal

Riverside Inn Hannibal
25.1 km from Mississippi River
United States
Jack
₩215,767
₩295,256 total
includes taxes & fees
Sep 14 - Sep 15
Riverside Inn Hannibal

6. Heritage Hotel Quincy

Heritage Hotel Quincy
47.8 km from Mississippi River
United States
Dustine
₩104,359
₩118,949 total
includes taxes & fees
Sep 13 - Sep 14
Heritage Hotel Quincy

7. Oak Hill Inn & Suites

Oak Hill Inn & Suites
71.8 km from Mississippi River
United States
Denny
₩135,663
₩154,622 total
includes taxes & fees
Sep 12 - Sep 13
Oak Hill Inn & Suites

8. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
30 km from Mississippi River
United States
Tom
₩110,831
₩128,953 total
includes taxes & fees
Sep 20 - Sep 21
Quality Inn & Suites Hannibal West

9. Stoney Creek Inn Quincy

Stoney Creek Inn Quincy
46.5 km from Mississippi River
United States
Kent
₩145,450
₩165,784 total
includes taxes & fees
Sep 13 - Sep 14
Stoney Creek Inn Quincy

10. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
26.2 km from Mississippi River
United States
Sandra
₩102,336
₩122,061 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites - Hannibal

11. Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown
47.8 km from Mississippi River
United States
Steve
₩148,070
₩168,769 total
includes taxes & fees
Oct 11 - Oct 12
Quality Inn & Suites Quincy - Downtown

12. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
112.5 km from Mississippi River
United States
Monica
₩120,587
₩141,977 total
includes taxes & fees
Sep 15 - Sep 16
Pear Tree Inn St. Louis Airport

13. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
112.1 km from Mississippi River
United States
Renae
₩192,960
₩204,499 total
includes taxes & fees
Sep 12 - Sep 13
Nauvoo Vacation Villas & Condos

14. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
26.1 km from Mississippi River
United States
Neal
₩77,707
₩89,633 total
includes taxes & fees
Sep 13 - Sep 14
Motel 6 Hannibal, MO

15. Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
112.5 km from Mississippi River
United States
Margaret
₩150,348
₩177,014 total
includes taxes & fees
Oct 5 - Oct 6
Wingate by Wyndham St. Louis Airport

16. Lighthouse Inn & Suites

Lighthouse Inn & Suites
25.8 km from Mississippi River
United States
Kari
₩240,501
₩277,418 total
includes taxes & fees
Sep 13 - Sep 14
Lighthouse Inn & Suites

17. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
26.4 km from Mississippi River
United States
PERRY
₩79,743
₩91,985 total
includes taxes & fees
Sep 13 - Sep 14
Days Inn by Wyndham Hannibal

18. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
104 km from Mississippi River
United States
Robert
₩194,287
₩225,231 total
includes taxes & fees
Sep 20 - Sep 21
Drury Plaza Hotel St. Louis St. Charles

19. Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
93.3 km from Mississippi River
United States
Serah
₩158,120
₩190,040 total
includes taxes & fees
Sep 13 - Sep 14
Holiday Inn Express & Suites St Peters by IHG

20. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
46.1 km from Mississippi River
United States
David
₩178,220
₩203,136 total
includes taxes & fees
Oct 11 - Oct 12
Holiday Inn Quincy East by IHG
View all properties

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Property grounds
River's Edge Motel
9.0
Wonderful
386 reviews
View
Restaurant
The Eagles Nest Inn
9.4
Exceptional
26 reviews
View
Exterior
Sleep Inn & Suites Hannibal West
9.6
Exceptional
1,001 reviews
View
Room
Best Western On The River
8.8
Excellent
1,004 reviews
View
Living room
Riverside Inn Hannibal
9.6
Exceptional
195 reviews
View

Top Mississippi River Hotel Reviews

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

8/10 Good
"Very nice hotel/casino with an outstanding amphitheatre for major concerts. The restaurant we chose was just OK. The various amenities are nice but extremely pricey. Definitely give the shuttle services 5 stars between the hotel and the amphitheatre. Room was clean except for some trash left under the sink. Beds comfy. Fridge in room didn’t work."
Jennifer 1-night trip
Posted less than an hour ago
Hollywood Casino & Hotel St. Louis
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"unique rooftop restaurant"
Sharon Henderson 2-night trip
Posted less than an hour ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"Free breakfast Free parking Pool Fridge Microwave"
Jason 4-night trip
Posted 1 hour ago
Clayton Plaza Hotel & Extended Stay
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Location fit my needs perfectly. The entire staff was excellent. Will definitely stay here when in St. Louis"
Rex 2-night trip
Posted 2 hours ago
Drury Plaza Hotel St. Louis at the Arch
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

8/10 Good
"I have stayed at this hotel a few times. The value is good - a better than expected hotel for the price. There were 2 issues for this last stay. I had a room with an adjacent wall to the elevator area, and the elevator is very loud and clunky when the door opens and shuts. I could hear it all day and all night long (good thing I had good earplugs). Make sure to get a room away from the elevator. Also, the cable tv system is a mess. The channels don't match what the cable guide on the TV says nor what the icon in the corner of the screen says. Also, many of the channels they're supposed to have say "no signal." Not a huge deal but definitely annoying. A simple piece of paper in the room which lists the real channels would certainly help."
John 3-night trip
Posted 9 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Awesome loved everything"
philip 1-night trip
Posted 21 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"My only complaint is there wasn’t a working ice machine on our floor. Other than that we had an excellent time and everything was great"
Matthew 2-night trip
Posted 1 day ago
Ameristar Casino Resort and Spa
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

8/10 Good
"The rooms and hotel were nice."
Lauren 1-night trip
Posted 2 days ago
Renaissance St. Louis Airport Hotel
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

10/10 Excellent
"Clean and comfortable. There was some peeling wallpaper in the bathroom but I could overlook that because everything else was so nice."
Kimberley 1-night trip
Posted 3 days ago
Hampton Inn St. Charles St. Peters

Other attractions near Mississippi River

Mark Twain Cave

8.8/10 (89 reviews)
You can find out about the history of Hannibal with a visit to Mark Twain Cave. While in this trendy area, you can savor the top-notch restaurants.
See properties

Sawyer's Creek Fun Park

7.8/10 (16 reviews)
Explore the great outdoors at Sawyer's Creek Fun Park, a lovely green space in Hannibal. While in this walkable area, you can savor the top-notch restaurants.
See properties

Lovers Leap

8.8/10 (171 reviews)
Find out about the history of Hannibal with a stop at Lovers Leap. While in this walkable area, you can savor the top-notch restaurants.
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Sodalis Nature Preserve

Explore the great outdoors at Sodalis Nature Preserve, a lovely green space in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Bluff City Theater

7.6/10 (5 reviews)
Enjoy a show at Bluff City Theater, a theater with a story to tell in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.
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Planters Barn Theater

8.8/10 (22 reviews)
Enjoy a show at Planters Barn Theater, a storied theater in Hannibal. While in this walkable area, you can savor the top-notch restaurants.
See properties

Mark Twain Boyhood Home and Museum

9.0/10 (278 reviews)
Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)
You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your travels to Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Find out more about Mississippi River

Top reasons to visit Mississippi River

  • Vibrant Activities: Enjoy baseball games, live music, and various sports along the river.
  • Cultural Heritage Festivals: Experience local culture at heritage festivals featuring food and music.
  • Outdoor Adventures: Engage in river studies, bird watching, and scenic day trips to appreciate nature.
  • Historic Attractions: Discover historic houses, museums, and caves that showcase the region's rich history.
  • Diverse Accommodations: Choose from cozy Bed & Breakfasts or comfortable hotels for a relaxing stay.

Find great hotels near Mississippi River

Discover the charm of the Mississippi River with a variety of accommodation options, including cozy Bed & Breakfasts and inviting guesthouses. Whether you're seeking family-friendly amenities, historic themes, or pet-friendly spaces, there's something for everyone. Explore the unique offerings of La Salle and unwind in wilderness cabins or stay at well-known chains like Hampton Inn for a comfortable retreat during your adventure along this iconic waterway.

  • Super 8 by Wyndham Bowling Green: Located 24km from the Mississippi River, Super 8 by Wyndham Bowling Green offers budget-friendly lodging with a guest rating of 8.4 out of 10. This hotel is ideal for travelers looking for affordability without sacrificing comfort. Guests can enjoy complimentary breakfast options available daily, including a to-go breakfast. The property features entertainment amenities such as a television with premium channels and a DVD player, ensuring a relaxing stay after a day of exploration.
  • River's Edge Motel: Just 13km away from the Mississippi River, River's Edge Motel boasts a commendable guest rating of 9.0 out of 10. This pet-friendly motel caters to travelers wishing to bring their furry companions along, with specific pet policies in place. Guests can expect a comfortable stay with amenities that accommodate pets, including fee waivers for service animals. The cozy atmosphere and proximity to the river make it a great choice for those seeking a relaxing getaway with their pets.
  • Riverside Inn Hannibal: Situated 26km from the Mississippi River, Riverside Inn Hannibal features guesthouse-style lodging with an impressive rating of 9.4 out of 10. The property offers dining at its on-site restaurant and a variety of entertainment options, including televisions equipped with Hulu and access to first-run movies. With a location near local attractions like the entertainment district and historical sites, it provides an engaging experience for guests looking to explore the charm of Hannibal.

Where to stay near Mississippi River

Your vacation along the Mississippi River promises a delightful blend of experiences, from the vibrant cities of Minneapolis and St. Louis to the serene landscapes of the Mississippi Delta. Enjoy friendly interactions with locals, explore family-friendly attractions, and embark on relaxing excursions along the scenic rivers. Don't miss the beautiful Minnesota River and the charming Iowa River, both offering unique atmospheres that highlight the warmth and hospitality of the region.

  • Louisiana: Nestled 14km from the Mississippi River, Louisiana offers a blend of outdoor adventure and scenic beauty. With visitor numbers peaking in April, July, and September, this city is a popular destination for those seeking a romantic getaway or a peaceful retreat. The recreational areas and vibrant theater scene provide entertainment options for all ages. Visitors can enjoy the stunning views of the nearby river and lake, along with the natural wonders found in the state park. Louisiana is perfect for travelers looking to immerse themselves in nature while enjoying a relaxed urban atmosphere.
  • New Canton: Located 11km away from the Mississippi River, New Canton is an inviting city that attracts families and outdoor enthusiasts alike. With peak travel seasons in January to February, April, August, and November, visitors can enjoy a variety of activities, including golfing at local courses and exploring the natural history museum. This city is ideal for those who appreciate the beauty of the environment and want to create family memories in a charming setting. The proximity to the river and lake adds to the scenic allure, making it a delightful spot for outdoor excursions.
  • Rockport: Just 13km from the Mississippi River, Rockport is a vibrant city known for its family-friendly atmosphere and urban charm. Peak visitor months include May, July, and September, attracting those interested in city-themed experiences and outdoor fun. Rockport offers a range of activities, including educational experiences, theater performances, and golfing opportunities. Visitors can explore the local urban park, delve into history at the museum, or enjoy the lively campus of the modern college university nearby. Rockport is a city that beautifully balances culture, education, and outdoor recreation.

Things to do in Mississippi River

Shopping

Visit the River Market in Downtown Memphis for local crafts and unique souvenirs. If you're up for a drive, check out the Mall of America in Bloomington, located over 16km away, featuring a wide range of shops, dining options, and entertainment to explore.

Recreation

In Mississippi, the River Valley Wellness offers yoga sessions and meditation workshops amidst serene landscapes. Nearby, the Golden Triangle offers nature trails for hiking and biking, allowing guests to immerse themselves in the tranquil environment while enjoying local flora and fauna.

Adventure

Experience the thrill of kayaking on the Mississippi River, where you can paddle through stunning landscapes and observe local wildlife. For the adventurous, join a riverboat cruise to enjoy breathtaking views while learning about the river's rich history and culture. Don’t miss the chance to fish in its abundant waters.

Nightlife

The nightlife along the Mississippi River offers vibrant experiences. Check out the lively bars in New Orleans for jazz and cocktails, or enjoy a riverboat cruise with dinner and entertainment. In Memphis, the Beale Street scene showcases blues music and bustling venues, perfect for a fun night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Mississippi River

The Mississippi River offers a variety of attractions for tourists, including historic houses, caves, and museums, perfect for those seeking cultural, outdoor, and adventurous experiences. Explore the amazing Mississippi River, its stunning delta, and the mighty upper Mississippi, or delve into the rich history of American rivers. There’s something for everyone to enjoy along this iconic waterway.

  • Mark Twain Boyhood Home and Museum: Located 26km from the Mississippi River, this historic site offers a glimpse into the early life of Samuel Clemens, better known as Mark Twain. Explore the charming home and engaging exhibits that reflect the culture and history of the time, enhancing your appreciation for Twain's literary contributions.
  • Mark Twain Cave: Situated 23km from the Mississippi River, this cave invites adventure enthusiasts to explore its winding passages. Discover the natural beauty of the cave while learning about its historical significance to Twain, who often drew inspiration from its depths for his writing.
  • Mark Twain Memorial Lighthouse: At 26km from the Mississippi River, this historic lighthouse stands as a tribute to Twain's legacy. Climb to the top for a stunning view of the river and the surrounding landscape, immersing yourself in the culture that inspired one of America's greatest authors.

The nearest major airports for your trip to Mississippi River

Traveling to the Mississippi River is easy with several nearby airports. Columbia Regional Airport (COU) is 122km away, with hotel options like The Broadway Columbia - a DoubleTree by Hilton, and voco The Tiger Hotel, both 18km from the airport. Lambert-St. Louis International Airport (STL) is 113km away, featuring luxury accommodations such as The Ritz-Carlton and Ameristar Casino Resort, both 11km from STL. Greater Peoria Regional Airport (PIA) is 175km away, with hotels like Embassy Suites by Hilton and Peoria Marriott Pere Marquette, both within 10km. Each hotel offers various transportation services to their respective airports.

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveler data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.