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Our top choices for Mississippi River hotels

The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (22 reviews)
"Best place to stay in town!"
United States
Kimberly
The price is ₩141,161
₩160,271 total
includes taxes & fees
May 9 - May 10
The Eagles Nest Inn

River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (363 reviews)
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
United States
Brent
The price is ₩118,101
₩134,089 total
includes taxes & fees
Apr 27 - Apr 28
River's Edge Motel

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
26.3 km from Mississippi River
6.4 out of 10, (761 reviews)
"the staff was Great!!"
United States
Karen Kay
The price is ₩98,171
₩113,997 total
includes taxes & fees
Apr 27 - Apr 28
Baymont by Wyndham Hannibal

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.4 out of 10, Exceptional, (171 reviews)
"Great place to stay!"
United States
Sandy
The price is ₩207,725
₩290,691 total
includes taxes & fees
Apr 28 - Apr 29
Riverside Inn Hannibal

Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.6 out of 10, Excellent, (1,007 reviews)
"Tony checked ys in, provided great touring and eating recommendations. The rooms were all updated, the location perfect to walk downtown"
United States
SUSAN
The price is ₩159,421
₩183,883 total
includes taxes & fees
Apr 27 - Apr 28
Best Western On The River

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,000 reviews)
"Room was great and breakfast was fantastic "
United States
Sheila
The price is ₩162,315
₩188,854 total
includes taxes & fees
May 17 - May 18
Sleep Inn & Suites Hannibal West

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
90.7 km from Mississippi River
6.8 out of 10, (1,000 reviews)
"Good stay. "
United States
Ted
The price is ₩97,891
₩115,462 total
includes taxes & fees
May 3 - May 4
Super 8 by Wyndham O'Fallon MO/St. Louis Area

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
86.8 km from Mississippi River
6.4 out of 10, (529 reviews)
"If you're just looking for a place to stay for a few days it's ok, However the decor is old and outdated"
United States
Nicko
The price is ₩103,338
₩117,237 total
includes taxes & fees
Apr 27 - Apr 28
Economy Inn Wentzville

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
8.8 out of 10, Excellent, (26 reviews)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is ₩235,188
₩322,374 total
includes taxes & fees
Apr 27 - Apr 28
Lighthouse Inn & Suites

Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
98 km from Mississippi River
6.8 out of 10, (1,001 reviews)
"Friendly staff. Good location"
United States
James
The price is ₩93,004
₩106,881 total
includes taxes & fees
Apr 27 - Apr 28
Relax Inn Saint Charles

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (687 reviews)
"Beds comfortable- nice breakfast choices. A pleasant peaceful setting "
United States
Wanda J
The price is ₩138,842
₩164,584 total
includes taxes & fees
May 3 - May 4
Comfort Inn & Suites - Hannibal

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
25.2 km from Mississippi River
8.4 out of 10, Very Good, (40 reviews)
"Very welcoming hosts, they went the extra mile and had a very comfortable bed! There were lots of cool antiques and they knew a lot of history on the home itself. We would recommend staying here again. "
United States
Andy Nicole
The price is ₩142,296
₩164,138 total
includes taxes & fees
May 1 - May 2
Garden House Bed and Breakfast

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very Good, (1,002 reviews)
"Great property, good breakfast. "
United States
Bree
The price is ₩111,354
₩129,571 total
includes taxes & fees
May 3 - May 4
Quality Inn & Suites Hannibal West

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,002 reviews)
"Great stay with no issues at all."
Canada
Thomas
The price is ₩82,656
₩95,352 total
includes taxes & fees
Apr 29 - Apr 30
Motel 6 Hannibal, MO

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (231 reviews)
"Park easy staff ok breakfast good room clean but restroom need upgrade "
United States
John
The price is ₩99,648
₩114,943 total
includes taxes & fees
Apr 27 - Apr 28
Days Inn by Wyndham Hannibal

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
96.1 km from Mississippi River
6.2 out of 10, (508 reviews)
" Very clean-nice room. Breakfast was just o k. Good location downtown but a little noisy being right on main street. Great place for the price. "
United States
Dan
The price is ₩111,605
₩124,995 total
includes taxes & fees
Apr 30 - May 1
Baymont by Wyndham Keokuk

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.2 out of 10, Good, (1,001 reviews)
"Property was clean and staff was friendly."
United States
Etta
The price is ₩103,338
₩119,208 total
includes taxes & fees
May 10 - May 11
Super 8 by Wyndham Hannibal

LAKEVIEWINN

LAKEVIEWINN
2.5 star property
89.4 km from Mississippi River
5.6 out of 10, (44 reviews)
"No view,the room was small ,and I'll never stay again."
United States
Tiffany
The price is ₩99,648
₩112,553 total
includes taxes & fees
May 3 - May 4
LAKEVIEWINN

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
26.3 km from Mississippi River
7.4 out of 10, Good, (163 reviews)
"Pet friendly, clean room, great staff and delicious breakfast "
United States
Melissa
The price is ₩86,952
₩100,947 total
includes taxes & fees
Apr 30 - May 1
Howard Johnson BY Wyndham Hannibal

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North

La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
3.0 star property
109.6 km from Mississippi River
6.6 out of 10, (1,003 reviews)
"Great stay"
United States
Micaela
The price is ₩104,962
₩128,316 total
includes taxes & fees
Apr 27 - Apr 28
La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Lunch and dinner served, Italian cuisine
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
22 reviews
View
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
363 reviews
View
Indoor pool
Baymont by Wyndham Hannibal
2.5 star property
6.4
761 reviews
View
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal
2.5 star property
9.4
Exceptional
171 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.6
Excellent
1,007 reviews
View

Top Mississippi River Hotel Reviews

Hotels near other Mississippi River attractions

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travelers like for its baseball games. When you want to settle in and find a place to stay, check out some of the hotels and other accommodations that Expedia offers in the area.
What's the best place to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveler data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Pear Tree Inn St. Louis Airport.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get top deals close to Mississippi River.
Where can I learn more about changing or cancelling my trip in the area near Mississippi River?
For additional details about updating your stay near Mississippi River or cancelling it, head over to our customer service page.