Panama City Vacations

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Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
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Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Find the Best Panama City Vacation Packages

Panama City Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ₩152,465 per night from Aug 25 to Aug 26
₩152,465
₩167,712 total
Aug 25 - Aug 26
includes taxes & fees
9/10 Wonderful! (4,180 reviews)
"Our stay was great! Everything was very clean and well-kept, and the service was excellent. The only downside was that the pool was under renovation during our visit, so we couldn’t use it. Otherwise, everything was wonderful!"

Reviewed on Aug 20, 2025

Hotel Riu Plaza Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is ₩113,115 per night from Aug 22 to Aug 23
₩113,115
₩124,427 total
Aug 22 - Aug 23
includes taxes & fees
9/10 Wonderful! (417 reviews)
"The Waymore is totally updated (stayed in a remodelled room. This used to be the Veneto hotel) and they did a good job. My room was large, comfortable, with all modern ammenities like rainshowers, expresso machine, smart tv. The pool and gym are large and breakfast was a good buffett. It is only ..."

Reviewed on Aug 18, 2025

Waymore Hotel Spa & Casino
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ₩187,292 per night from Aug 31 to Sep 1
₩187,292
₩206,021 total
Aug 31 - Sep 1
includes taxes & fees
8.4/10 Very Good! (930 reviews)
"Very nice experience"

Reviewed on Aug 20, 2025

Sheraton Grand Panama
See all 1,453 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Panama City

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Panama City skyline during the day #seetheworld

Uruguay Street

During your visit to Panama City, you can do some window-shopping at Uruguay Street. While in this family-friendly area, you can savor the top-notch restaurants.

Uruguay Street
UNESCO site, Casco Viejo

Metropolitan Cathedral of Panama

Learn about the local history of Panama City when you take a trip to Metropolitan Cathedral of Panama. Check out the shops and top-notch restaurants in this vibrant area.

Metropolitan Cathedral of Panama

Frequently asked questions

How much does a Panama City vacation package cost?
You can pick up a vacation package to this destination on Expedia. However, how much your vacation to Panama City costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Panama City?
You're likely to find lower rates and better availability in September, October and November. Take a look at our cheap Panama City vacation packages and you could get some great off-season discounts.
How many days is enough for Panama City?
Dedicate around 3 days for your Panama City vacation in order to discover everything that makes this destination special. Stroll around popular areas, including San Francisco and Campo Alegre. Then check out major sights such as Metropolitan Cathedral of Panama and National Theater. With a good itinerary, you can keep busy with room for some rest time too. Want to travel beyond Panama City? Consider squeezing in an excursion or two.
Is it worth booking a vacation package to Panama City?
Popular for its nature, nightlife and culture, a Panama City vacation is a hit with all types of travelers. Be sure to visit leading sights like Albrook Shopping Mall and Cinta Costera, and consider renting a car for day trips to explore even more.
How to find the best Panama City package deals?
Landing a cheap Panama City package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Panama City package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Panama City vacation as a package?
You can enjoy significant savings on your Panama City getaway by booking a personalized vacation package. Click on the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Panama City?
Enjoy incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Panama City trip.
How to plan a trip to Panama City?

  1. Choose when to go: Check your schedule and get your bags packed. Your preferred time of year and the available activities will also help you decide when to visit Panama City.
  2. Plan your budget wisely: As well as the cost of your stay, you'll need to factor in other expenses too. These include food, flights and transportation. Also, put aside a little extra for unexpected costs that could arise during your trip to Panama City.
  3. Work out your trip length: Think about how long you want to spend exploring Panama City. Plan your itinerary so you can get to all the attractions and activities you're interested in at a leisurely pace.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customized Panama City vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.