Panama City Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ₩234,741 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Where to stay in Panama City
Downtown Panama City
While visiting Downtown Panama City, you might make a stop by sights like Panama City Marina and St. Andrews Bay.
Find the Best Panama City Vacation Packages
Panama City Beach Vacation
There's nothing more delightful than a Panama City vacation. Whether you're treating yourself to delicious cocktails at a local bar or reading your favorite magazine by the water's edge, your trip to Panama City is an ideal time to live out your beachy fantasies. Many travelers stay close to Carillon Beach, situated just 35 kilometers from the center of town. However, you'll also discover plenty of Panama City vacation packages close to Panama City Beaches and Mexico Beach, two other popular nearby options.
Things You Should Know About Panama City
- Choosing a hotel close to the water means crisp sea breezes and slow walks along the beach at twilight. Browse our Panama City beach hotels and see what's available.
- Lots of travelers also choose to spend their getaway in condos here. Sunny 4brwalk 2 Mins to Beach 4 Bedrooms 4 Bathrooms Townhouse and Gulf Crest Condominium #1604 - 2 Br Condo are a few options to select from.
- Alternatively, go for one of our All-Inclusive hotels in Panama City. They make budgeting a breeze. Leave your purse in your room and enjoy the freedom that comes with going all-inclusive.
- Panama City, population 38,300, is popular for countless reasons. Discover some handy tips on our Panama City things to do page.
- Pier Park is one big sight you can't miss here. For plenty of other great ideas to add to your itinerary, browse our Panama City vacation deals.
Panama City Hotel Deals
Comfort Inn & Suites Panama City North
All of the above was great
Reviewed on Nov 10, 2025
La Quinta Inn & Suites by Wyndham Panama City
Room was a good size.. Comfortable beds. Plenty of parking. Good hotel for the value and price
Reviewed on Nov 5, 2025
Best Western Plus Panama City Hotel
The staff was amazing!!!! Super sweet and helpful!!! The room was spotless, comfortable and breakfast was great! Will definitely be coming back to stay
Reviewed on Nov 11, 2025
Discover the most popular places to visit in Panama City
Gulf Coast State College
With a beautiful setting on the Grand Lagoon, this college offers 150 program choices and welcomes visitors for arts and athletic events.
Visual Arts Center of Northwest Florida
You can spend time studying the exhibits at Visual Arts Center of Northwest Florida in Panama City. Wander the beautiful beaches and seaside in this family-friendly area.
Science and Discovery Center of Northwest Florida
You can take time to visit Science and Discovery Center of Northwest Florida during your travels to Panama City. Attend a sporting event or discover the beautiful sunsets in this family-friendly area.
