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Our top choices for Santo Spirito hotels

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (232 reviews)
"Great location and great rooms"
United States
David
La Torre Del Cestello

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (611 reviews)
"Lovely clean, quiet and safe hotel. really good breakfast and staff. Good location within walking distance to everything. "
United Kingdom
Shaunna
The price is ₩160,490
₩200,467 total
includes taxes & fees
Jan 25 - Jan 26
Hotel Horto Convento

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (102 reviews)
"It was a great stay. The renovation style is very tasteful. "
Singapore
Maoying
The price is ₩224,649
₩271,042 total
includes taxes & fees
Jan 19 - Jan 20
Oltrarno Splendid

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.4 out of 10, Exceptional, (46 reviews)
"Excellent place to stay!"
United States
Diane
The price is ₩150,438
₩185,992 total
includes taxes & fees
Feb 10 - Feb 11
Palazzo D'Oltrarno - Residenza D'Epoca

Casa Santo Nome di Gesù

Casa Santo Nome di Gesù
Santo Spirito
8.8 out of 10, Excellent, (342 reviews)
"Really a nice place, like the room style and good for family stay!"
United States
Ning
Casa Santo Nome di Gesù

Home in Florence

Home in Florence
Santo Spirito
9.0 out of 10, Wonderful, (70 reviews)
"Perfect place, super friendly owners, really helpful. "
United Kingdom
Paul
The price is ₩114,667
₩146,644 total
includes taxes & fees
Jan 19 - Jan 20
Home in Florence

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (137 reviews)
"Ver clean and quiet, wonderful stay."
United States
kevin
Drom Florence Rooms & Apartments

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (222 reviews)
"Loved my stay at this Hotel. Everything about it was wonderful. The staff was warm and welcoming, the location was in what is now the more interesting and authentic part of Florence. The Terrace overlooking the Gardens where you can eat breakfast was dazzling. In this age of ultra modern hotels, this one stood out because of its preservation of history and yet the room and the bathroom were large and roomy yet warm and cozy. "
United States
monica
The price is ₩264,293
₩314,650 total
includes taxes & fees
Jan 25 - Jan 26
AdAstra Suites

Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,079 reviews)
"Perfect stay"
United States
Juan P
Palazzo Mannaioni Suites

UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze
4.0 star property
Santo Spirito
8.4 out of 10, Very Good, (1,000 reviews)
"Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back!"
United States
JINHEE
The price is ₩129,350
₩166,213 total
includes taxes & fees
Feb 1 - Feb 2
UNA Hotels Vittoria Firenze

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (172 reviews)
"The room was beautiful and clean, the staff was pleasant, breakfast was fantastic, 10/10"
United States
Dan
The price is ₩134,247
₩168,182 total
includes taxes & fees
Jan 19 - Jan 20
La Fonderia Firenze

Santo Spirito Venti

Santo Spirito Venti
Santo Spirito
8.8 out of 10, Excellent, (59 reviews)
"Great location, friendly staff, I definitely recommend it."
Canada
Pedro
Santo Spirito Venti

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (169 reviews)
"Great location and extremely charming!"
United States
Brook
The price is ₩296,086
₩349,623 total
includes taxes & fees
Jan 28 - Jan 29
Ottantotto Firenze

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
8.8 out of 10, Excellent, (139 reviews)
"Our stay was wonderful! Roxy was so welcoming and helpful! The room and view was beautiful as well! Great location with amazing food and sights nearby! "
United States
Jacqueline
Residenza D'Epoca Al Numero 8

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
9.0 out of 10, Wonderful, (2 reviews)
"Nice stay. Location was slightly off the beaten track, which we liked. Staff were responsive to us on the phone immediately. Nice flat."
United States
Christopher Pat
The price is ₩107,411
₩292,484 total
includes taxes & fees
Feb 1 - Feb 2
Mamo Florence - Bice & Krizia Apartments

Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (189 reviews)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is ₩86,653
₩110,701 total
includes taxes & fees
Jan 28 - Jan 29
Hotel Firenze 2000

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
9.0 out of 10, Wonderful, (21 reviews)
"Very goord place to stay"
United States
Victor
The price is ₩109,073
₩140,490 total
includes taxes & fees
Jan 19 - Jan 20
L'Antica Porta Boutique B&B

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (24 reviews)
"This boutique was an absolute must stay. From the location to the comfort of our room and the lovely staff, it was all you could ask for during a stay in Florence. The walkability was incredible, and even though there is a lively crowd nightly outside of the building, your room is peaceful. Highly recommend this hotel to anyone looking for a unique stay in Florence! "
United States
Chris
The price is ₩232,131
₩275,854 total
includes taxes & fees
Jan 20 - Jan 21
SPIRIT OF FLORENCE Boutique Rooms

B&B Mia Palace

B&B Mia Palace
Santo Spirito
8.4 out of 10, Very Good, (112 reviews)
"Extremely helpful and friendly staff."
United States
Julie
The price is ₩99,369
₩129,816 total
includes taxes & fees
Jan 21 - Jan 22
B&B Mia Palace

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (178 reviews)
"Our stay here was wonderful! The host was so pleasant and the view from the terrace was beautiful. The location was in a great spot for enjoying the Florentine neighborhoods, and close to many of the restaurants recommended to us. We would stay here again in a heartbeat."
United States
Bianca
1900 Artevita
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Piazza di Santa Maria Novella and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Porta Romana and Piazza Santo Spirito as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 7-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favorite options in the area include AdAstra Suites and Hotel Horto Convento.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 461 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
Where can I learn more about changing or cancelling my trip to Santo Spirito?
To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Porta Romana and Piazza Santo Spirito are some other places worth a visit. A few places to visit in the area around Santo Spirito include Piazza di Santa Maria Novella, Piazza del Carmine, and Santa Maria della Carmine. When you're sightseeing in Florence, Brancacci Chapel and Il Nabucco di Matteo Gabellini are also worth a stop.