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Our top choices for Santo Spirito hotels

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
8.0 out of 10, Very Good, (5 reviews)
"Very nice apartment and great location. The included parking and laundry facilities were the reason we selected the property, and were very happy with everything. Overall a lovely stay. "
United States
Michele
The price is ₩312,927
₩571,853 total
includes taxes & fees
Jun 3 - Jun 4
Mamo Florence - Bice & Krizia Apartments

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (178 reviews)
"The room was beautiful and clean, the staff was pleasant, breakfast was fantastic, 10/10"
United States
Dan
The price is ₩292,211
₩342,126 total
includes taxes & fees
May 12 - May 13
La Fonderia Firenze

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (206 reviews)
"The staff was amazing."
United States
Jason
The price is ₩184,129
₩223,236 total
includes taxes & fees
May 8 - May 9
Foresteria Valdese di Firenze - Casa per Ferie

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
9.0 out of 10, Wonderful, (22 reviews)
"Very goord place to stay"
United States
Victor
The price is ₩198,097
₩238,601 total
includes taxes & fees
May 7 - May 8
L'Antica Porta Boutique B&B

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (184 reviews)
"Huge room on the outskirts of the city centre. Lovely area with great restaurants. The room was exceptionally clean, the downside was the very hard bed as we prefer a softer bed. We would definitely come back here if we returned to Florence."
United Kingdom
Gillian
The price is ₩225,541
₩268,789 total
includes taxes & fees
May 13 - May 14
1900 Artevita

Le Volte by Mmega

Le Volte by Mmega
Santo Spirito
The price is ₩208,209
₩387,684 total
includes taxes & fees
Jun 4 - Jun 5
Le Volte by Mmega

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (170 reviews)
"Great location and extremely charming!"
United States
Brook
The price is ₩504,979
₩579,620 total
includes taxes & fees
Jun 4 - Jun 5
Ottantotto Firenze

Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (194 reviews)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is ₩181,589
₩215,268 total
includes taxes & fees
May 5 - May 6
Hotel Firenze 2000

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (252 reviews)
"It was in a great location, we had an excellent view from our room."
United States
Tonya
The price is ₩257,498
₩307,391 total
includes taxes & fees
May 5 - May 6
La Torre Del Cestello

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (116 reviews)
"Beautiful boutique hotel, rooms are large and comfortable. The staff are amazing, breakfast is delicious, the location is the best - close to lots of amazing and authentic eating options. Would highly recommend "
United Kingdom
Elizabeth
The price is ₩591,189
₩674,450 total
includes taxes & fees
May 19 - May 20
Oltrarno Splendid

Mamo Florence - Maddalena Apartment

Mamo Florence - Maddalena Apartment
Santo Spirito
8.8 out of 10, Excellent, (3 reviews)
"As advertised, the stairs to reach the apartment were quite a work out. The is a nice clothes washing machine but no dryer, so plan for the provided drying rack. Everything was very nice!"
United States
Geoff
The price is ₩175,472
₩360,295 total
includes taxes & fees
May 5 - May 6
Mamo Florence - Maddalena Apartment

Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is ₩841,554
₩949,852 total
includes taxes & fees
May 5 - May 6
Torre di Bellosguardo

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.6 out of 10, Exceptional, (51 reviews)
"Excellent place to stay!"
United States
Diane
The price is ₩349,126
₩404,732 total
includes taxes & fees
May 25 - May 26
Palazzo D'Oltrarno - Residenza D'Epoca

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (143 reviews)
"Very cute suite with what we thought was a great location in Florence. Away from the hustle and bustle but very walkable to main sites and lots in the close vicinity as well. Claudia was a great host and very responsive. Beds were comfy’ linens and towels were good. We couldn’t use the AC as it was too early in the season. But the apartment cooled off very well at night. A lovely stay!"
Canada
Denise
The price is ₩162,338
₩199,266 total
includes taxes & fees
May 5 - May 6
Drom Florence Rooms & Apartments

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (153 reviews)
"Excellent location and very friendly staff."
Canada
Scott
The price is ₩233,983
₩281,525 total
includes taxes & fees
May 6 - May 7
Residenza D'Epoca Al Numero 8

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (227 reviews)
"Gorgeous room in a beautiful property, very helpful staff, tranquil setting"
United Kingdom
Olivia
The price is ₩666,276
₩757,054 total
includes taxes & fees
May 10 - May 11
AdAstra Suites

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"Easy check in and very helpful and polite "
United States
Remi
The price is ₩522,758
₩595,728 total
includes taxes & fees
May 5 - May 6
SPIRIT OF FLORENCE Boutique Rooms

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.6 out of 10, Excellent, (37 reviews)
"Great stay! The place was clean, comfortable, and exactly as described. Would definitely stay again"
United States
Diana
The price is ₩127,848
₩299,287 total
includes taxes & fees
May 11 - May 12
Appartamenti degli Artisti by Mmega

Cosimo by MMega

Cosimo by MMega
Santo Spirito
9.0 out of 10, Wonderful, (14 reviews)
"Great location just by the river, lovey cafe at the front and the ice cream shop on the corner! The apartment was clean, tidy had everything you needed. We would stay here again! "
United Kingdom
Martin
The price is ₩187,388
₩399,271 total
includes taxes & fees
Jun 3 - Jun 4
Cosimo by MMega

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (647 reviews)
"Great hotel all around and great breakfast. Highly recommend and will go back when in Florence"
Canada
John-Anthony
The price is ₩543,875
₩622,405 total
includes taxes & fees
May 26 - May 27
Hotel Horto Convento
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Piazza Santo Spirito and Arno River as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on our traveler data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighborhood include Palazzo Mannaioni Suites and La Torre Del Cestello.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 496 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
Where can I learn more about changing or cancelling my trip to Santo Spirito?
To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Piazza Santo Spirito and Piazza del Carmine are some other places worth a visit. Favorite places to visit in the surrounding area include Piazza di Santa Maria Novella, Uffizi Gallery, and Cathedral of Santa Maria del Fiore. When you're sightseeing in Florence, Santa Maria della Carmine and Brancacci Chapel are also worth a stop.