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Our top choices for South San Francisco hotels

citizenM Menlo Park
citizenM Menlo Park

The Marina Inn on San Francisco Bay
The Marina Inn on San Francisco Bay

Best Western Inn & Suites San Mateo - San Francisco Airport
Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Plus Grosvenor Airport Hotel
Best Western Plus Grosvenor Airport Hotel

Hampton Inn San Francisco Airport
Hampton Inn San Francisco Airport

DoubleTree by Hilton San Francisco South Airport Blvd
DoubleTree by Hilton San Francisco South Airport Blvd
Great weekend hotel deals in South San Francisco, CA
Image gallery for La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Check out hotels with an airport shuttle in South San Francisco

Hotel Focus SFO
Hotel Focus SFO
Hotels with free breakfast in South San Francisco you'll enjoy

Hampton Inn San Francisco Airport
Hampton Inn San Francisco Airport
These family-friendly hotels in South San Francisco may fit your trip

Hilton Garden Inn San Francisco Arpt North
Hilton Garden Inn San Francisco Arpt North
Where to stay in South San Francisco

Downtown South San Francisco
Downtown South San Francisco blends business energy with cultural richness just minutes from San Francisco proper. Modern biotech campuses stand alongside vibrant ethnic markets on Grand Avenue. The neighborhood hums with professional activity while celebrating its diverse heritage through colorful murals. This well-connected hub offers excellent transportation options via BART and Caltrain stations. Authentic dining reflects the area's Hispanic and Asian communities. After business hours, the atmosphere becomes quietly residential with limited evening entertainment.

Oyster Point
Oyster Point blends sleek biotech campuses with refreshing waterfront beauty along San Francisco Bay. Modern glass buildings reflect the calm waters where walking paths invite you to explore. The area showcases contemporary plazas and public art installations throughout the business district. Corporate lunch spots serve the weekday crowd while evening options remain limited. The Bay Trail offers panoramic views and peaceful walks away from the office buzz. Visitors can observe both cutting-edge architecture and natural bay ecosystems during business hours.
The East Side
The East Side of South San Francisco blends cultural diversity with suburban charm just minutes from San Francisco Bay. Hispanic and Asian communities contribute authentic flavors to local eateries along Grand Avenue. Views of San Bruno Mountain create a distinctive backdrop for this working-class neighborhood. Visitors can explore Orange Memorial Park's recreational areas or hike nearby mountain trails. Budget-conscious travelers appreciate the area's affordable dining options and practical accommodations. Easy connections to BART and Caltrain make exploring the greater Bay Area convenient without downtown's premium prices.

Paradise Valley
Paradise Valley offers a quiet retreat from San Francisco's hustle while keeping you connected to the Bay Area. This peaceful residential neighborhood boasts wide streets and modest homes where local families live their everyday lives. Travelers appreciate the genuine suburban atmosphere and significantly lower prices than downtown. Just minutes from San Francisco International Airport, Paradise Valley serves as a practical base for exploring the region. Small local parks provide green spaces for relaxation. Though lacking tourist attractions within its boundaries, the neighborhood's proximity to major highways makes Bay Area adventures easily accessible.
Serra Highlands
Serra Highlands offers a peaceful retreat from the Bay Area bustle. This quiet neighborhood features hillside streets lined with mid-century ranch homes and contemporary houses. Morning fog creates a mystical atmosphere while eucalyptus-scented air refreshes the senses. Panoramic vistas of San Francisco Bay reward those who explore the residential streets. Small neighborhood parks and green corridors provide pleasant walking opportunities. Though dining and shopping options are limited within the area, the authentic suburban charm makes it worth the short drive to nearby commercial districts.
Stay near popular South San Francisco attractions

Golden Gate Park
This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

Pier 39
This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.
Learn more about South San Francisco
South San Francisco is calling! Discover its food, castle, sightseeing, and more.

Top South San Francisco Hotel Reviews
More cheap stays in South San Francisco
More cheap stays in South San Francisco

The Marina Inn on San Francisco Bay
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in South San Francisco Neighborhoods
Stay near popular South San Francisco attractions
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