A calm lake surrounded by trees and vegetation.

Southwest Illinois, Illinois hotel rooms at the La Quinta Inn & Suites

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Check prices for these dates

Tonight
Sep 21 - Sep 22
Tomorrow
Sep 22 - Sep 23
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Southwest Illinois La Quinta Inn & Suites

1. La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
Eastport
United States
Donna
₩127,501
₩146,601 total
includes taxes & fees
Sep 27 - Sep 28
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

2. La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
O'Fallon
United States
Tahjae
₩104,237
₩119,852 total
includes taxes & fees
Sep 22 - Sep 23
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

3. La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
Granite City
United States
Weldon
₩151,390
₩174,068 total
includes taxes & fees
Sep 22 - Sep 23
La Quinta Inn & Suites by Wyndham Pontoon Beach
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Top Southwest Illinois Hotel Reviews

Baymont by Wyndham Marion

Baymont by Wyndham Marion

8/10 Good
"although not new the hotel was in good condition and the price was acceptable"
Marcus 1-night trip
Posted 1 hour ago
Baymont by Wyndham Marion
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

8/10 Good
"Comfortable room. Breakfast was just ok."
Sam 1-night trip
Posted 4 hours ago
Comfort Inn Edwardsville - St. Louis
Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, Fairview Heights, IL

8/10 Good
"Interior decoration public spaces and guestrooms similar to upscale hotels. Unexpected benefits: refrigerator, microwave, hundreds of TV stations, shower/bath, beds made and turned down upscale hotel, easy wifi, hot breakfast, delicious coffee, equipped workout room, very quiet as requested 3rd floor."
Jean 1-night trip
Posted 6 hours ago
Country Inn & Suites by Radisson, Fairview Heights, IL
Drury Inn & Suites Marion

Drury Inn & Suites Marion

8/10 Good
"This Hotel was lovely. But pets are allowed. And a dog was in the bathroom above us and continued to bark. We called the staff but they could not hear it in the hall. Since people pay to have their animals with them, I cannot understand why the staff did not know who to contact. We were traveling and needed rest."
eileen 1-night trip
Posted 7 hours ago
Drury Inn & Suites Marion
The Principal Hotel

The Principal Hotel

10/10 Excellent
"The restaurant next-door is apet of the hotel. Great food and good staff in both."
brian 1-night trip
Posted 8 hours ago
The Principal Hotel
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"The place is clean and the staff was great!"
colleen 1-night trip
Posted 19 hours ago
Comfort Suites Mount Vernon
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"The room was big and had a nice couch. Bed was comfy, towels were soft. We ordered a sandwich from the app, which was very easy. Food was good and reasonably priced. The breakfast had a nice variety of hot items… pancakes, waffles, potatoes, sausage, eggs etc. Staff were very friendly and checked on us during breakfast to make sure we were satisfied. Would definitely hear again!!! I also overheard that the pool and hot tub were great!"
Karen 1-night trip
Posted 21 hours ago
Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"I have stated at this hotel several times over the years and keep coming back. The people the rooms are amazingLy clean very convenient short drive to St. Louis short drive to shopping. Great food around in the area"
TONY 2-night trip
Posted 22 hours ago
Drury Inn & Suites St. Louis Fairview Heights
Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Caseyville, IL - Caseyville Il

10/10 Excellent
"Is very good and good staff"
emma 1-night trip
Posted 2 days ago
Motel 6 Caseyville, IL - Caseyville Il

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