A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

Find Luxury Hotels in St. Charles, MO

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Check availability on St. Charles Luxury Hotels

Tonight
Oct 14 - Oct 15
Tomorrow
Oct 15 - Oct 16
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for St. Charles luxury hotels

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
₩235,232
₩297,203 total
includes taxes & fees
Nov 15 - Nov 16
Ameristar Casino Resort and Spa

2. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Chesterfield
  • Chesterfield hotel offers plush comforts with indoor tennis courts, dual pools, and premium bedding.
₩186,064
₩215,812 total
includes taxes & fees
Nov 15 - Nov 16
DoubleTree by Hilton Hotel St. Louis - Chesterfield

3. The Cheshire

The Cheshire
Richmond Heights
₩199,263
₩236,599 total
includes taxes & fees
Nov 15 - Nov 16
The Cheshire

4. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
₩171,846
₩204,101 total
includes taxes & fees
Nov 15 - Nov 16
Drury Plaza Hotel St. Louis Brentwood

5. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
₩216,167
₩294,504 total
includes taxes & fees
Nov 15 - Nov 16
The Royal Sonesta Chase Park Plaza St. Louis

6. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Indulge in artistic luxury at this downtown St. Louis hotel with spa services and indoor pool.
₩192,872
₩232,237 total
includes taxes & fees
Nov 15 - Nov 16
21C Museum Hotel St Louis

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Ritz-Carlton elegance defines this St. Louis retreat with indulgent spa services and dining excellence.
₩778,031
₩908,254 total
includes taxes & fees
Nov 1 - Nov 2
The Ritz-Carlton, St. Louis

8. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
  • Opulent downtown retreat with pillowtop beds, soaking tubs, and Italian dining moments from Busch Stadium.
₩176,062
₩205,867 total
includes taxes & fees
Nov 15 - Nov 16
The Westin St. Louis

9. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
₩503,494
₩588,725 total
includes taxes & fees
Oct 28 - Oct 29
Four Seasons Hotel St Louis

10. The Inn at Elijah McLeans

The Inn at Elijah McLeans
Washington
₩181,258
₩206,363 total
includes taxes & fees
Oct 18 - Oct 19
The Inn at Elijah McLeans
View all properties

Top St. Charles Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"Terrace view was an amazing photo opportunity. Very quite throughout our stay. Room was immaculately clean and all linen was crispy, clean and glowing white."
Michael 2-night trip
Posted 5 hours ago
Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Great location! The hotel is within walking distance of many places, making it easy to explore the area. The Ferris wheel is right in front of the hotel, which is such a nice touch! Even if you don’t take a ride, just enjoying the beautiful view is worth it. .😊"
Meijing 2-night trip
Posted 6 hours ago
Drury Plaza Hotel St. Louis Union Station
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"Everything was clean and everyone was very friendly. Loved Lavern and her singing. Will definitely stay again. This was our first time at a drury inn"
Rubene 2-night trip
Posted 11 hours ago
Drury Plaza Hotel St. Louis at the Arch
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent
"Excellent location. Good parking. Clean rooms."
Tommye 1-night trip
Posted 11 hours ago
Country Inn & Suites by Radisson, St. Charles Historic District
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent
"Loved the nightly snack and drink. Breakfast was great as well"
Tyler 3-night trip
Posted 3 days ago
Embassy Suites by Hilton St. Louis St. Charles

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Charles?
During your visit, you might want to enjoy the casinos and shopping which St. Charles is known for.
What's the best luxury hotel in St. Charles?
Ameristar Casino Resort and Spa is a luxury hotel with 6 restaurants and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
When can I expect good weather in St. Charles?
Planning for the weather is an important factor for making your trip to St. Charles a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do in St. Charles?
When you're in St. Charles, enjoy exploring the sights and attractions here including Historic Main Street, Katy Trail, and Lewis & Clark Boathouse and Nature Center. If you have a little extra time during your trip, you might want to make a stop at St Charles Convention Center and Ameristar Casino St. Charles.

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