Find Resorts & Hotels with Spas in St. Louis, MO

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Resorts & Hotels with Spas

Tonight
Oct 28 - Oct 29
Tomorrow
Oct 29 - Oct 30
This weekend
Oct 31 - Nov 2
Next weekend
Nov 7 - Nov 9

Top St. Louis Resorts & Hotels with Spas

Massages
21C Museum Hotel St Louis
21C Museum Hotel St Louis
4.5 star property
9.0 out of 10, Wonderful, (1431)
"Great location for an event we attended."
United States
Catherine
The price is ₩217,939
₩254,834 total
includes taxes & fees
Nov 23 - Nov 24
21C Museum Hotel St Louis
Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
4.5 star property
8.4 out of 10, Very Good, (1012)
"Great place to stay.Will visit again."
United States
Shameka
The price is ₩235,286
₩298,745 total
includes taxes & fees
Nov 16 - Nov 17
Ameristar Casino Resort and Spa
Couples treatment rooms, hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
5.0 star property
9.4 out of 10, Exceptional, (1003)
"Beautiful stay at the four seasons! "
United States
Maria
The price is ₩608,808
₩711,873 total
includes taxes & fees
Oct 31 - Nov 1
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
5.0 star property
9.2 out of 10, Wonderful, (551)
"Service is exceptional!!!"
United States
Jorge
The price is ₩772,112
₩901,351 total
includes taxes & fees
Oct 30 - Oct 31
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top St. Louis Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Stayed here many times. I especially love the breakfast."
Austin 1-night trip
Posted 18 hours ago
Clayton Plaza Hotel & Extended Stay

Explore a world of travel with Expedia

Frequently asked questions

Looking to vacation at a spa hotel in St. Louis?
Soothe the senses with some time in one of our wonderful spa hotels. Travelers love the fascinating museums and live music scene in St. Louis so get ready for a cultural tour. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in St. Louis?
Four Seasons Hotel St Louis is a top luxury spa hotel featuring a rooftop terrace, a 24-hour fitness center, a hair salon, and a bar. Enjoy a facial, body scrub, or body wrap at the onsite spa. Another popular spa hotel in St. Louis is Ameristar Casino Resort and Spa.
How many spa hotels will I find in St. Louis?
Among Expedia's 1762 accommodation options in St. Louis, there are 2 spa hotels.
What's there to see and do in St. Louis?
Experience St. Louis and visit St. Louis Union Station, Busch Stadium, and Gateway Arch. If you have spare time during your trip, you might want to make a stop at St. Louis Aquarium at Union Station and Energizer Park.
What is a St. Louis spa hotel?
Spa hotels in St. Louis provide lodging and have an on-site spa offering services like couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.