Find Resorts & Hotels with Spas in St. Louis, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Resorts & Hotels with Spas

Our top choices for St. Louis hotels with a spa

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1,001 reviews)
"The room was great. I enjoyed my stay. "
United States
Wanda
The price is ₩284,096
₩355,978 total
includes taxes & fees
Feb 24 - Feb 25
Ameristar Casino Resort and Spa
Massages

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,602 reviews)
"Everything was great i can’t wait to stay again "
United States
Kimbriel
The price is ₩194,221
₩234,342 total
includes taxes & fees
Feb 22 - Feb 23
21C Museum Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,000 reviews)
"Great service, great staff , room service food really good,, great view of the arch and the river. "
United States
Jose
The price is ₩598,173
₩699,430 total
includes taxes & fees
Feb 15 - Feb 16
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (557 reviews)
"Excellent hotel with various restaurants and expansive lobby area.. staff very attentive."
United States
Diane M
The price is ₩722,717
₩843,686 total
includes taxes & fees
Feb 15 - Feb 16
The Ritz-Carlton, St. Louis
Luxury Room, 1 King Bed, Jetted Tub, Garden View | Bathroom | Free toiletries, hair dryer, towels, soap

Beall Mansion An Elegant Bed & Breakfast Inn

Beall Mansion An Elegant Bed & Breakfast Inn
4.0 star property
Alton
10.0 out of 10, Exceptional, (37 reviews)
"Wonderful stay! This home is beautiful. Our hosts Sandy and Jim were gracious and it was a pleasure to be with them for the evening. Highly recommended!"
United States
Jeff
The price is ₩429,531
₩489,578 total
includes taxes & fees
Mar 16 - Mar 17
Beall Mansion An Elegant Bed & Breakfast Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in St. Louis

Pool
Hot tub

Top St. Louis Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Considering the price I wasn’t expecting such a nice place, from the entrance, to the easy parking, to the amazing breakfast… everything was so great and I would 1000% consider this place for my future stays in St. Louis! The staff was also very helpful and friendly!"
Lillian 1-night trip
Posted 18 hours ago
Clayton Plaza Hotel & Extended Stay

Frequently asked questions

Looking to vacation at a spa hotel in St. Louis?
Soothe the senses with some time in one of our wonderful spa hotels. Travelers love the fascinating museums and live music scene in St. Louis so get ready for a cultural tour. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in St. Louis?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, and a 24-hour fitness center. Treat yourself to a facial, body scrub, or hydrotherapy at Ara. Another popular spa hotel in St. Louis is Four Seasons Hotel St Louis.
How many spa hotels will I find in St. Louis?
Among Expedia's 1849 accommodation options in St. Louis, there are 2 spa hotels.
What's there to see and do in St. Louis?
Experience St. Louis and visit St. Louis Union Station, Busch Stadium, and Gateway Arch. If you have spare time during your trip, you might want to make a stop at St. Louis Aquarium at Union Station and The St. Louis Wheel.
What is a St. Louis spa hotel?
Spa hotels in St. Louis provide lodging and have an on-site spa offering services like couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.