The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Oct 30 - Nov 1
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Nov 6 - Nov 8

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Our top choices for West Main Historic District hotels

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

1. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (2,204 reviews)
"Beautiful Hotel"
United States
Kristan
The price is ₩269,358
₩316,927 total
includes taxes & fees
Nov 16 - Nov 17
Omni Louisville Hotel
A balcony with a view of a river, a bridge, and a cityscape.

2. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (4,422 reviews)
"Great place to stay!!!"
United States
Shun
The price is ₩180,438
₩212,304 total
includes taxes & fees
Nov 8 - Nov 9
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

3. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,389 reviews)
"Great room, excellent staff, exceptional breakfast, very clean."
United States
Chase
The price is ₩161,959
₩190,561 total
includes taxes & fees
Nov 23 - Nov 24
Embassy Suites Louisville Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.

4. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is ₩201,674
₩243,918 total
includes taxes & fees
Nov 22 - Nov 23
21c Museum Hotel Louisville
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

5. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place"
United States
MILTON
The price is ₩210,056
₩247,152 total
includes taxes & fees
Nov 28 - Nov 29
Louisville Marriott Downtown
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

6. The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,007 reviews)
"I really enjoyed my stay and hope to return soon."
United States
Donna
The price is ₩206,760
₩243,275 total
includes taxes & fees
Nov 15 - Nov 16
The Grady
A spacious lobby with a central escalator, seating areas, and modern lighting.

7. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,000 reviews)
"amazing location will definitely be back"
United States
Michael Jered
The price is ₩167,023
₩196,519 total
includes taxes & fees
Nov 25 - Nov 26
Hyatt Regency Louisville
A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

8. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,010 reviews)
"Location was perfect and staff was very friendly."
United States
Sarah
The price is ₩126,195
₩148,481 total
includes taxes & fees
Nov 22 - Nov 23
Cambria Hotel Louisville Downtown-Whiskey Row
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

9. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,000 reviews)
"Staff very friendly"
United States
peter
The price is ₩151,090
₩177,772 total
includes taxes & fees
Nov 23 - Nov 24
Homewood Suites by Hilton Louisville Downtown, KY
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

10. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (860 reviews)
"Hotel was super clean and staff were friendly in a great location"
United States
Sheree
The price is ₩150,014
₩176,506 total
includes taxes & fees
Nov 25 - Nov 26
Moxy Louisville Downtown
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

11. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,000 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is ₩162,145
₩190,780 total
includes taxes & fees
Nov 23 - Nov 24
Aloft by Marriott Louisville Downtown
A modern lobby with a central seating area, a reception desk, and a large screen.

12. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1,838 reviews)
"Great buffet breakfast"
United States
Lisa
The price is ₩115,325
₩135,690 total
includes taxes & fees
Nov 25 - Nov 26
Holiday Inn Express & Suites Louisville Downtown by IHG
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

13. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (169 reviews)
"Great location for whiskey row! Everyone was so and we wish we’d have had another night!! Highly recommend!"
United States
Adrienne Tremonti
The price is ₩173,087
₩203,654 total
includes taxes & fees
Nov 23 - Nov 24
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

14. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,000 reviews)
"Very good hotel, a lot of history on it"
United States
Leonardo
The price is ₩189,028
₩222,411 total
includes taxes & fees
Nov 26 - Nov 27
Seelbach Hilton Louisville Downtown
A rooftop terrace with seating, a view of the city skyline, and modern architecture.

15. Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,008 reviews)
"Excellent location if seeing a concert at the Palace."
United States
james
The price is ₩129,350
₩152,192 total
includes taxes & fees
Nov 23 - Nov 24
Hilton Garden Inn Louisville Downtown
An outdoor seating area with wicker furniture and a fire pit.

16. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (815 reviews)
"Comfortable rooms within walking distance to breweries. Nice breakfast and friendly staff."
United States
Barbara
The price is ₩146,032
₩171,820 total
includes taxes & fees
Nov 22 - Nov 23
Towneplace Suites By Marriott Louisville Downtown
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

17. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
West Main Historic District
9.6 out of 10, Exceptional, (513 reviews)
"Very clean / helpful and accommodating staff / excellent restaurant"
United States
Kimberly
The price is ₩267,530
₩314,777 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Distil, Autograph Collection
A lobby with a reception desk, seating area, and a fireplace.

18. Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very good, (1,007 reviews)
"Great Location"
Canada
Eric
The price is ₩134,082
₩157,761 total
includes taxes & fees
Nov 5 - Nov 6
Fairfield Inn & Suites by Marriott Louisville Downtown
A hotel room with two beds, a TV, and a desk.

19. SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,000 reviews)
"Great location. Clean rooms. Nice staff."
United States
Kim
The price is ₩134,082
₩157,770 total
includes taxes & fees
Nov 26 - Nov 27
SpringHill Suites by Marriott Louisville Downtown
A Courtyard by Marriott hotel with a modern brick facade, multiple floors, and a prominent sign.

20. Courtyard by Marriott Louisville Downtown

Courtyard by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,000 reviews)
"Room was very clean, great hospitality, our balcony was right across the street from the yum center where we saw Dave Chappelle. Will definitely stay again."
United States
Jessica
The price is ₩149,430
₩175,819 total
includes taxes & fees
Nov 5 - Nov 6
Courtyard by Marriott Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in West Main Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
513 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,000 reviews
View
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,204 reviews
View
A classical gold statue in front of a multi-story building with large windows and a brick facade.
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,002 reviews
View
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
The Grady
4.0 star property
9.4
Exceptional
1,007 reviews
View

Hotels recommended for families in West Main Historic District

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,389)
The price is ₩161,959
₩190,561 total
includes taxes & fees
Nov 23 - Nov 24
Embassy Suites Louisville Downtown

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most.
A steamboat docked at a pier with a bridge in the background.

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

A historical marker for the Conrad-Caldwell House, detailing its architectural style and history.

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

A nighttime hot air balloon festival with colorful balloons, including one labeled "OLIVER WINERY."
Photo by Hyelsinta
Open Photo by Hyelsinta

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

A city skyline at dusk with illuminated buildings reflecting on the water.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Top West Main Historic District Hotel Reviews

The Grady

The Grady

8/10 Good
"Walls are very thin, can hear your neighbors as if they are sharing the room with you."
David P. 1-night trip
Posted 3 hours ago
The Grady

Frequently asked questions

What's it like in West Main Historic District?
Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.
Where is the best hotel for a stay in West Main Historic District?
Based on our traveler data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 234 West Main Historic District hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.
Where can I learn more about changing or cancelling my trip to West Main Historic District?
For more details about picking new dates or cancelling your trip to West Main Historic District, go to https://www.expedia.com/service/.
What is there to do around this Louisville neighborhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. 21c Museum Hotel and Muhammad Ali Center are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Louisville Science Center and Kentucky Museum of Art and Craft are a couple of additional sights to visit in Louisville.