The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Sep 18 - Sep 20
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Sep 25 - Sep 27

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Our top choices for West Main Historic District hotels

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

1. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,002 reviews)
"Location was great"
United States
Steve
The price is ₩188,770
₩222,106 total
includes taxes & fees
Oct 13 - Oct 14
Homewood Suites by Hilton Louisville Downtown, KY

2. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1,815 reviews)
"Super nice spot close to every thing you need to see in the city"
United States
Carlos
The price is ₩160,841
₩189,246 total
includes taxes & fees
Sep 22 - Sep 23
Holiday Inn Express & Suites Louisville Downtown by IHG
An outdoor seating area with wicker furniture and a fire pit.

3. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (764 reviews)
"Great comfortable room for our quick night stay."
United States
Scott
The price is ₩166,293
₩195,660 total
includes taxes & fees
Oct 11 - Oct 12
Towneplace Suites By Marriott Louisville Downtown
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,362 reviews)
"Great location clean hotel and friendly staff."
United States
Maurica
The price is ₩222,424
₩261,704 total
includes taxes & fees
Oct 11 - Oct 12
Embassy Suites Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

5. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (4,274 reviews)
"Great place to stay!"
United States
Jacob
The price is ₩221,381
₩260,476 total
includes taxes & fees
Oct 4 - Oct 5
Galt House Hotel Trademark Collection by Wyndham
A lobby with a reception desk, seating area, and a fireplace.

6. Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very good, (1,006 reviews)
"Overall a great property, perfect location."
United States
Mark
The price is ₩149,460
₩175,855 total
includes taxes & fees
Oct 12 - Oct 13
Fairfield Inn & Suites by Marriott Louisville Downtown
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

7. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (2,143 reviews)
"Amazing stay and loved the pool!"
United States
Kara
The price is ₩380,566
₩447,774 total
includes taxes & fees
Sep 30 - Oct 1
Omni Louisville Hotel
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

8. The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,001 reviews)
"Very nice hotel"
United States
Bruce
The price is ₩240,631
₩283,127 total
includes taxes & fees
Oct 18 - Oct 19
The Grady
A spacious lobby with a central escalator, comfortable seating areas, and modern lighting fixtures.

9. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,001 reviews)
"Very clean, quiet and helpful staff. Close to convention centre and restaurants."
Canada
Sandra
The price is ₩250,614
₩294,872 total
includes taxes & fees
Oct 4 - Oct 5
Hyatt Regency Louisville
A classical gold statue in front of a multi-story building with large windows and a brick facade.

10. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,001 reviews)
"Great staff!"
United States
Candice
The price is ₩291,442
₩349,794 total
includes taxes & fees
Oct 18 - Oct 19
21c Museum Hotel Louisville
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

11. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (839 reviews)
"Was a great place and great experience with the staff. Highly recommend this place"
United States
Bryan
The price is ₩174,472
₩205,282 total
includes taxes & fees
Oct 4 - Oct 5
Moxy Louisville Downtown
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

12. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,001 reviews)
"Great stay"
United States
Jacobi
The price is ₩291,886
₩343,434 total
includes taxes & fees
Oct 4 - Oct 5
Louisville Marriott Downtown
A spacious lobby with leather sofas, round tables, and ottomans, featuring large windows and modern lighting fixtures.

13. Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,001 reviews)
"Great stay!"
United States
Kooper
The price is ₩177,198
₩208,490 total
includes taxes & fees
Oct 12 - Oct 13
Residence Inn by Marriott Louisville Downtown
A hotel room with a bed, a chair, a nightstand, and a wall-mounted lamp.

14. Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown
2.0 star property
West Main Historic District
7.0 out of 10, Good, (1,001 reviews)
"Close to restaurants and nightlife"
United States
Stacie
The price is ₩95,005
₩111,783 total
includes taxes & fees
Oct 12 - Oct 13
Econo Lodge Louisville Downtown
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

15. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,001 reviews)
"Great place to stay location was perfect"
United States
Angela
The price is ₩184,722
₩217,343 total
includes taxes & fees
Oct 4 - Oct 5
Aloft by Marriott Louisville Downtown
A modern kitchen with wooden cabinets, a long countertop, and a variety of food items displayed.

16. SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,000 reviews)
"The staff was super friendly and helpful. By far the best staff. Rooms were clean and showers were amazing"
United States
Beau
The price is ₩161,045
₩189,486 total
includes taxes & fees
Oct 12 - Oct 13
SpringHill Suites by Marriott Louisville Downtown
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

17. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,000 reviews)
"Great experience."
United States
DAVID
The price is ₩254,974
₩300,003 total
includes taxes & fees
Sep 21 - Sep 22
Seelbach Hilton Louisville Downtown
A modern restaurant with hanging light fixtures, a bar area, and various seating options.

18. Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,007 reviews)
"The staff was above and beyond helpful! Great Downtown location within walking distance from so many things! Would definitely stay again!"
United States
Elizabeth
The price is ₩149,773
₩176,224 total
includes taxes & fees
Oct 12 - Oct 13
Hilton Garden Inn Louisville Downtown
A modern bar area with a circular bar, multiple seating options, and a large screen.

19. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,007 reviews)
"The staff was very helpful"
United States
Larry
The price is ₩164,138
₩193,126 total
includes taxes & fees
Oct 18 - Oct 19
Cambria Hotel Louisville Downtown-Whiskey Row
An indoor swimming pool with clear blue water, surrounded by lounge chairs and large windows.

20. Hampton Inn Louisville Downtown

Hampton Inn Louisville Downtown
2.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,002 reviews)
"The room is clean, the parking is easy and the breakfast is great!"
United States
Wen
The price is ₩142,958
₩168,204 total
includes taxes & fees
Oct 13 - Oct 14
Hampton Inn Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in West Main Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,002 reviews
View
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
The Grady
4.0 star property
9.4
Exceptional
1,001 reviews
View
A classical gold statue in front of a multi-story building with large windows and a brick facade.
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,001 reviews
View
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,143 reviews
View
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
9.4
Exceptional
155 reviews
View

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most.
A steamboat docked at a pier with a bridge in the background.

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

A nighttime hot air balloon festival with colorful balloons, including one labeled "OLIVER WINERY."
Photo by Hyelsinta
Open Photo by Hyelsinta

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

A city skyline at dusk with illuminated buildings reflecting on the water.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

A historical marker for the Conrad-Caldwell House, detailing its architectural style and history.

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

Top West Main Historic District Hotel Reviews

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

8/10 Good
"Nice"
susan 3-night trip
Posted 2 hours ago
Embassy Suites Louisville Downtown

Frequently asked questions

What's it like in West Main Historic District?
Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.
Where is the best hotel for a stay in West Main Historic District?
Based on our traveler data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 235 West Main Historic District hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.
Where can I learn more about changing or cancelling my trip to West Main Historic District?
For more details about picking new dates or cancelling your trip to West Main Historic District, go to https://www.expedia.com/service/.
What is there to do around this Louisville neighborhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. 21c Museum Hotel and Muhammad Ali Center are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Louisville Science Center and Kentucky Museum of Art and Craft are a couple of additional sights to visit in Louisville.