The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Oct 30 - Nov 1
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Nov 6 - Nov 8

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Our top choices for West Main Historic District hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (4,449 reviews)
"Great place to stay!!!"
United States
Shun
The price is ₩180,099
₩211,904 total
includes taxes & fees
Nov 8 - Nov 9
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

2. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (2,209 reviews)
"Beautiful Hotel"
United States
Kristan
The price is ₩269,358
₩316,927 total
includes taxes & fees
Nov 16 - Nov 17
Omni Louisville Hotel
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

3. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,001 reviews)
"Great place"
United States
MILTON
The price is ₩167,876
₩197,523 total
includes taxes & fees
Nov 27 - Nov 28
Louisville Marriott Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.

4. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,009 reviews)
"It was a great stay! The room and location were perfect, and the staff were very accommodating!"
United States
Matt
The price is ₩201,674
₩243,918 total
includes taxes & fees
Nov 22 - Nov 23
21c Museum Hotel Louisville
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

5. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,389 reviews)
"Excellent stay"
United States
Frances
The price is ₩161,959
₩190,561 total
includes taxes & fees
Nov 23 - Nov 24
Embassy Suites Louisville Downtown
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

6. The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,006 reviews)
"I really enjoyed my stay and hope to return soon."
United States
Donna
The price is ₩206,452
₩242,910 total
includes taxes & fees
Nov 15 - Nov 16
The Grady
A modern bar area with a circular bar, multiple seating options, and a large screen.

7. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,009 reviews)
"Location was perfect and staff was very friendly."
United States
Sarah
The price is ₩126,195
₩148,481 total
includes taxes & fees
Nov 22 - Nov 23
Cambria Hotel Louisville Downtown-Whiskey Row
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

8. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,000 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is ₩162,145
₩190,780 total
includes taxes & fees
Nov 23 - Nov 24
Aloft by Marriott Louisville Downtown
A spacious lobby with a central escalator, seating areas, and modern lighting.

9. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,003 reviews)
"amazing location will definitely be back"
United States
Michael Jered
The price is ₩167,023
₩196,519 total
includes taxes & fees
Nov 25 - Nov 26
Hyatt Regency Louisville
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

10. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,006 reviews)
"Staff very friendly"
United States
peter
The price is ₩151,090
₩177,772 total
includes taxes & fees
Nov 24 - Nov 25
Homewood Suites by Hilton Louisville Downtown, KY
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

11. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (860 reviews)
"Hotel was super clean and staff were friendly in a great location"
United States
Sheree
The price is ₩159,070
₩187,162 total
includes taxes & fees
Nov 15 - Nov 16
Moxy Louisville Downtown
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (168 reviews)
"Great location for whiskey row! Everyone was so and we wish we’d have had another night!! Highly recommend!"
United States
Adrienne Tremonti
The price is ₩172,829
₩203,350 total
includes taxes & fees
Nov 23 - Nov 24
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern lobby with a central seating area, a reception desk, and a large screen.

13. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1,845 reviews)
"Great buffet breakfast"
United States
Lisa
The price is ₩149,791
₩176,263 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Express & Suites Louisville Downtown by IHG
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

14. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,007 reviews)
"Very good hotel, a lot of history on it"
United States
Leonardo
The price is ₩189,028
₩222,411 total
includes taxes & fees
Nov 26 - Nov 27
Seelbach Hilton Louisville Downtown
A modern restaurant with hanging light fixtures, a bar area, and various seating options.

15. Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,008 reviews)
"Excellent location if seeing a concert at the Palace."
United States
james
The price is ₩129,350
₩152,192 total
includes taxes & fees
Nov 23 - Nov 24
Hilton Garden Inn Louisville Downtown
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.

16. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
West Main Historic District
9.6 out of 10, Exceptional, (513 reviews)
"The room exceeded expectations! All of the restaurants had exceptional food! Beautiful hotel, great location, and very friendly staff!"
United States
Heather
The price is ₩267,131
₩314,307 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Distil, Autograph Collection
An outdoor seating area with wicker furniture and a fire pit.

17. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (814 reviews)
"great breakfast"
United States
Derek
The price is ₩145,814
₩171,565 total
includes taxes & fees
Nov 22 - Nov 23
Towneplace Suites By Marriott Louisville Downtown
A lobby with a reception desk, seating area, and a fireplace.

18. Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very good, (1,007 reviews)
"Great Location"
Canada
Eric
The price is ₩134,082
₩157,761 total
includes taxes & fees
Oct 28 - Oct 29
Fairfield Inn & Suites by Marriott Louisville Downtown
A modern kitchen with wooden cabinets, a long countertop, and a variety of food items displayed.

19. SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,004 reviews)
"Great location. Clean rooms. Nice staff."
United States
Kim
The price is ₩134,082
₩157,770 total
includes taxes & fees
Nov 22 - Nov 23
SpringHill Suites by Marriott Louisville Downtown
A Courtyard by Marriott hotel with a modern brick facade, multiple floors, and a prominent sign.

20. Courtyard by Marriott Louisville Downtown

Courtyard by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,006 reviews)
"Room was very clean, great hospitality, our balcony was right across the street from the yum center where we saw Dave Chappelle. Will definitely stay again."
United States
Jessica
The price is ₩152,707
₩179,675 total
includes taxes & fees
Nov 27 - Nov 28
Courtyard by Marriott Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in West Main Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
513 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,006 reviews
View
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,209 reviews
View
A classical gold statue in front of a multi-story building with large windows and a brick facade.
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,009 reviews
View
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
The Grady
4.0 star property
9.4
Exceptional
1,006 reviews
View

Hotels recommended for families in West Main Historic District

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,389)
The price is ₩161,959
₩190,561 total
includes taxes & fees
Nov 23 - Nov 24
Embassy Suites Louisville Downtown

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most.
A steamboat docked at a pier with a bridge in the background.

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

A historical marker for the Conrad-Caldwell House, detailing its architectural style and history.

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

A nighttime hot air balloon festival with colorful balloons, including one labeled "OLIVER WINERY."
Photo by Hyelsinta
Open Photo by Hyelsinta

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

A city skyline at dusk with illuminated buildings reflecting on the water.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Top West Main Historic District Hotel Reviews

Omni Louisville Hotel

Omni Louisville Hotel

10/10 Excellent
"The pool was fantastic, and the hotel really was top notch... I feel like I got a luxury hotel for an economy price!"
Mickolus 2-night trip
Posted 3 hours ago
Omni Louisville Hotel

Frequently asked questions

What's it like in West Main Historic District?
Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.
Where is the best hotel for a stay in West Main Historic District?
Based on our traveler data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 234 West Main Historic District hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.
Where can I learn more about changing or cancelling my trip to West Main Historic District?
For more details about picking new dates or cancelling your trip to West Main Historic District, go to https://www.expedia.com/service/.
What is there to do around this Louisville neighborhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. 21c Museum Hotel and Muhammad Ali Center are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Louisville Science Center and Kentucky Museum of Art and Craft are a couple of additional sights to visit in Louisville.