Find hotels in West Main Historic District, Louisville from ₩95,875

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 10 - Nov 11
Tomorrow
Nov 11 - Nov 12
This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for West Main Historic District hotels

A balcony with a view of a river, a bridge, and a cityscape.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (4,486 reviews)
"Great place to stay!!!"
United States
Shun
The price is ₩182,933
₩215,239 total
includes taxes & fees
Nov 24 - Nov 25
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

2. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (2,230 reviews)
"Very very nice property clean well taken care of and great staff would stay again"
United States
James
The price is ₩238,947
₩281,144 total
includes taxes & fees
Nov 24 - Nov 25
Omni Louisville Hotel
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

3. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is ₩204,462
₩247,291 total
includes taxes & fees
Dec 6 - Dec 7
21c Museum Hotel Louisville
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

4. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice hotel"
United States
Jeanette
The price is ₩154,281
₩181,527 total
includes taxes & fees
Nov 24 - Nov 25
Homewood Suites by Hilton Louisville Downtown, KY
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

5. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,392 reviews)
"Overall great stay. The resteraunt downstairs is awesome too."
United States
Clay
The price is ₩164,199
₩193,196 total
includes taxes & fees
Nov 24 - Nov 25
Embassy Suites Louisville Downtown
A spacious lobby with a central escalator, seating areas, and modern lighting.

6. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,003 reviews)
"Highly recommend staying here. Very clean rooms and friendly staff!!"
United States
Charity
The price is ₩181,630
₩213,706 total
includes taxes & fees
Nov 24 - Nov 25
Hyatt Regency Louisville
A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

7. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,023 reviews)
"Clean and bathrooms are nice I will be staying again."
United States
Trista
The price is ₩129,976
₩152,930 total
includes taxes & fees
Nov 30 - Dec 1
Cambria Hotel Louisville Downtown-Whiskey Row
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

8. The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,011 reviews)
"Our stay at The Grady was exceptional and we will definitely be back to stay again soon!!"
United States
Greg
The price is ₩190,499
₩224,151 total
includes taxes & fees
Nov 22 - Nov 23
The Grady
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

9. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,003 reviews)
"Great place"
United States
MILTON
The price is ₩228,959
₩269,393 total
includes taxes & fees
Nov 22 - Nov 23
Louisville Marriott Downtown
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

10. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (862 reviews)
"Hotel was super clean and staff were friendly in a great location"
United States
Sheree
The price is ₩154,278
₩181,524 total
includes taxes & fees
Nov 25 - Nov 26
Moxy Louisville Downtown
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

11. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,002 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is ₩154,988
₩182,359 total
includes taxes & fees
Nov 23 - Nov 24
Aloft by Marriott Louisville Downtown
A modern lobby with a central seating area, a reception desk, and a large screen.

12. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1,842 reviews)
"Great buffet breakfast"
United States
Lisa
The price is ₩111,545
₩131,243 total
includes taxes & fees
Dec 8 - Dec 9
Holiday Inn Express & Suites Louisville Downtown by IHG
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

13. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (178 reviews)
"Very good breakfast in hotel lobby restaurant. Extremely nice servers. Reasonably priced."
United States
Paul
The price is ₩189,202
₩222,615 total
includes taxes & fees
Nov 26 - Nov 27
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

14. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,000 reviews)
"Very good hotel, a lot of history on it"
United States
Leonardo
The price is ₩194,690
₩229,071 total
includes taxes & fees
Nov 26 - Nov 27
Seelbach Hilton Louisville Downtown
A rooftop terrace with seating, a view of the city skyline, and modern architecture.

15. Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,004 reviews)
"The staff was nice."
United States
Kim
The price is ₩129,970
₩152,923 total
includes taxes & fees
Dec 8 - Dec 9
Hilton Garden Inn Louisville Downtown
An outdoor seating area with wicker furniture and a fire pit.

16. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (830 reviews)
"Nice stay, bed was comfortable"
United States
Brandi
The price is ₩132,433
₩155,821 total
includes taxes & fees
Dec 7 - Dec 8
Towneplace Suites By Marriott Louisville Downtown
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

17. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
West Main Historic District
9.6 out of 10, Exceptional, (519 reviews)
"Excellent location and room!"
United States
Athina
The price is ₩270,825
₩318,652 total
includes taxes & fees
Dec 6 - Dec 7
Hotel Distil, Autograph Collection
A Courtyard by Marriott hotel with a modern brick facade, multiple floors, and a prominent sign.

18. Courtyard by Marriott Louisville Downtown

Courtyard by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,002 reviews)
"Room was very clean, great hospitality, our balcony was right across the street from the yum center where we saw Dave Chappelle. Will definitely stay again."
United States
Jessica
The price is ₩124,514
₩146,504 total
includes taxes & fees
Nov 29 - Nov 30
Courtyard by Marriott Louisville Downtown
An indoor swimming pool with clear blue water, surrounded by lounge chairs and large windows.

19. Hampton Inn Louisville Downtown

Hampton Inn Louisville Downtown
2.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,004 reviews)
"Clean room, great staff, and immensities was wonderful"
United States
LaShanda
The price is ₩109,360
₩128,673 total
includes taxes & fees
Nov 28 - Nov 29
Hampton Inn Louisville Downtown
A lobby with a reception desk, seating area, and a fireplace.

20. Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very good, (1,002 reviews)
"Great Location"
Canada
Eric
The price is ₩124,513
₩146,501 total
includes taxes & fees
Nov 24 - Nov 25
Fairfield Inn & Suites by Marriott Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in West Main Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
519 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,003 reviews
View
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
9.4
Exceptional
178 reviews
View
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,003 reviews
View
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
The Grady
4.0 star property
9.4
Exceptional
1,011 reviews
View

Hotels recommended for families in West Main Historic District

A balcony with a view of a river, a bridge, and a cityscape.

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,486)
The price is ₩182,933
₩215,239 total
includes taxes & fees
Nov 24 - Nov 25
Galt House Hotel Trademark Collection by Wyndham

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most.
A steamboat docked at a pier with a bridge in the background.

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

A historical marker for the Conrad-Caldwell House, detailing its architectural style and history.

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

A nighttime hot air balloon festival with colorful balloons, including one labeled "OLIVER WINERY."
Photo by Hyelsinta
Open Photo by Hyelsinta

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

A city skyline at dusk with illuminated buildings reflecting on the water.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Top West Main Historic District Hotel Reviews

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
Downtown Louisville

10/10 Excellent

Nice hotel
United States
Jeanette
Reviewed November 9, 2026
Homewood Suites by Hilton Louisville Downtown, KY

Frequently Asked Questions

What's it like in West Main Historic District?

Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.

Where is the best hotel for a stay in West Main Historic District?

Based on our traveler data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.

How many hotels will I find in the West Main Historic District area?

If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 234 West Main Historic District hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.

Where can I learn more about changing or cancelling my trip to West Main Historic District?

For more details about picking new dates or cancelling your trip to West Main Historic District, go to https://www.expedia.com/service/.

What is there to do around this Louisville neighborhood?

For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. 21c Museum Hotel and Muhammad Ali Center are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Louisville Science Center and Kentucky Museum of Art and Craft are a couple of additional sights to visit in Louisville.