Find Gay friendly Hotels in Florence, SC

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Check availability on Florence Gay friendly Hotels

Tonight
Dec 28 - Dec 29
Tomorrow
Dec 29 - Dec 30
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Our top choices for Florence LGBT-friendly hotels

Exterior
Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.6 out of 10, Exceptional, (535)
"The staff was great and the room was very clean"
United States
Mark Whitehurst
The price is ₩161,466
₩175,997 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Latta by IHG
Terrace/patio
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1002)
"We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. "
United States
Marita
The price is ₩134,766
₩155,999 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Tru by Hilton Florence I-95
Exterior
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1005)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is ₩164,349
₩184,071 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (826)
"We had our dog and the room was good and dog amenities helpful."
United States
Cynthia
The price is ₩165,157
₩184,975 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Hampton Inn & Suites Florence-North-I-95
Indoor pool
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1005)
"Very good breakfast & convenient location"
United States
Diedre
The price is ₩158,583
₩177,614 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Free daily continental breakfast
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
2.5 star property
Hartsville
8.6 out of 10, Excellent, (681)
"very friendly older property but clean"
United States
Tamiko
The price is ₩121,315
₩135,873 total
includes taxes & fees
Jan 17 - Jan 18, 2026
Fairfield Inn by Marriott Hartsville
Front of property
Best Western Inn

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.6 out of 10, Good, (1004)
"very clean and quiet"
United States
Marissa
The price is ₩128,308
₩143,704 total
includes taxes & fees
Dec 30 - Dec 31
Best Western Inn
View from property
Residence Inn Marriott Florence

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (489)
"Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day"
United States
Marialinda
The price is ₩143,013
₩160,174 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Residence Inn Marriott Florence
Reception
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (826)
"My go to stay while in Fairfax. "
United States
Gregory
The price is ₩140,677
₩157,559 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hampton Inn & Suites Florence Center
Exterior
TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (710)
"Good stay, great staff"
United States
James
The price is ₩148,779
₩166,631 total
includes taxes & fees
Dec 30 - Dec 31
TownePlace Suites by Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florence Hotel Reviews

Frequently asked questions

Searching for a gay-friendly accommodation in Florence?
Whether you are traveling with your partner or flying solo, you'll find gay-friendly hotels in Florence on our website. Staying in this welcoming area will give you access to its shops and restaurants.
What is the favorite LGBTQ-friendly place to stay in Florence?
TownePlace Suites by Marriott Florence is a top LGBTQ-friendly hotel that features free breakfast and free parking. Tru by Hilton Florence I-95 and Courtyard by Marriott Florence are two other good options for your stay.
How many gay-friendly hotels will I find in Florence?
There are currently 18 LGBTQ-friendly places to stay in Florence.
What should I see while I'm in Florence?
During your vacation, get out and discover all that Florence has to offer. You and your traveling companions may want to visit Florence Museum, Florence National Cemetery, and Dr. Eddie Floyd Tennis Center. While you're here, create some great memories of your trip with stops at Magnolia Mall, Florence Veterans Park, and Florence Civic Center.
What is a gay-friendly hotel in Florence?
LGBTQ-friendly hotels are places where lesbian, gay, bisexual, and transgender travelers are proudly welcomed. We have worked with the International Gay and Lesbian Travel Association (IGLTA) to compile a selection of gay-friendly hotels worldwide. In Florence, hotels affiliated with IGLTA prioritize a diverse environment in which guests are welcomed, respected, and not obliged to declare or hide their sexual orientation.
What can I expect from a gay-friendly hotel in Florence?
Take a vacation from the ordinary; stay at a gay-friendly hotel in Florence, and you won't have to hide or your sexuality or your gender identity when you check-in. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer community-specific packages, exclusive tours, and opportunities for social interaction.