Find hotels near Mission Hope Cancer Center, Santa Maria from ₩85,058

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mission Hope Cancer Center hotels

Reception
Hotel Avanti

Hotel Avanti

Hotel Avanti
2.5 star property
2.3 km from Mission Hope Cancer Center
9.0 out of 10, Wonderful, (284)
"The rooms were surprisingly nice. "
United States
mario
The price is ₩120,213
₩135,239 total
includes taxes & fees
Dec 28 - Dec 29
Hotel Avanti
Restaurant
Best Western Plus Big America

Best Western Plus Big America

Best Western Plus Big America
2.5 star property
2.8 km from Mission Hope Cancer Center
8.8 out of 10, Excellent, (1002)
"Room was fabulous as was the staff."
United States
Laura
The price is ₩157,141
₩176,791 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Best Western Plus Big America
Restaurant
Historic Santa Maria Inn

Historic Santa Maria Inn

Historic Santa Maria Inn
3.5 star property
2.2 km from Mission Hope Cancer Center
8.4 out of 10, Very Good, (1867)
"Nice place to stay "
United States
octaviano
The price is ₩110,685
₩124,521 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Historic Santa Maria Inn
Reception
ECONOMY INN

ECONOMY INN

ECONOMY INN
2.5 star property
2.1 km from Mission Hope Cancer Center
8.0 out of 10, Very Good, (74)
"Decent hotel for the price"
United States
ydalid
The price is ₩75,607
₩85,058 total
includes taxes & fees
Dec 30 - Dec 31
ECONOMY INN
Classic Room | Desk, free WiFi
Villa Motel

Villa Motel

Villa Motel
2.0 star property
2.4 km from Mission Hope Cancer Center
8.0 out of 10, Very Good, (177)
"Staff was very friendly "
United States
erika
The price is ₩93,708
₩105,422 total
includes taxes & fees
Dec 28 - Dec 29
Villa Motel
Premium bedding, in-room safe, blackout drapes, iron/ironing board
Travelodge by Wyndham Santa Maria

Travelodge by Wyndham Santa Maria

Travelodge by Wyndham Santa Maria
2.0 star property
2.9 km from Mission Hope Cancer Center
7.8 out of 10, Good, (1000)
"Great establishment and surrounding neighborhood. "
United States
Julio
The price is ₩143,373
₩161,294 total
includes taxes & fees
Dec 28 - Dec 29
Travelodge by Wyndham Santa Maria
Outdoor pool
Days Inn by Wyndham Santa Maria

Days Inn by Wyndham Santa Maria

Days Inn by Wyndham Santa Maria
2.0 star property
0.8 km from Mission Hope Cancer Center
6.8 out of 10, (1000)
"Room was clean staff was nice. "
United States
Kimberly Dawn
The price is ₩103,416
₩116,343 total
includes taxes & fees
Dec 29 - Dec 30
Days Inn by Wyndham Santa Maria
View from property
Buckboard Motel

Buckboard Motel

Buckboard Motel
2.5 star property
3 km from Mission Hope Cancer Center
6.8 out of 10, (71)
"Excellent place to rest excellent price "
United States
Carlos
The price is ₩90,104
₩101,363 total
includes taxes & fees
Dec 28 - Dec 29
Buckboard Motel
Lobby
Motel 6 Santa Maria, CA - South

Motel 6 Santa Maria, CA - South

Motel 6 Santa Maria, CA - South
2.0 star property
0.5 km from Mission Hope Cancer Center
5.8 out of 10, (511)
"Room was nice and the owner and staff were helpful and kind."
United States
Jason
The price is ₩110,789
₩124,636 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Motel 6 Santa Maria, CA - South
Reception
Hampton Inn & Suites Santa Maria

Hampton Inn & Suites Santa Maria

Hampton Inn & Suites Santa Maria
2.5 star property
3.7 km from Mission Hope Cancer Center
9.4 out of 10, Exceptional, (1004)
"Breakfast very good, Parkin field safe ,the room very clean"
United States
Hugo
The price is ₩171,096
₩192,817 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Hampton Inn & Suites Santa Maria
Property amenity
Fairfield Inn & Suites by Marriott Santa Maria

Fairfield Inn & Suites by Marriott Santa Maria

Fairfield Inn & Suites by Marriott Santa Maria
2.5 star property
3.3 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (726)
"Clean room and great staff and service! "
United States
Ruby
The price is ₩161,466
₩181,964 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Fairfield Inn & Suites by Marriott Santa Maria
Restaurant
Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria
3.0 star property
3.5 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (40)
"Room was great and the staff were extremely courteous and helpful! Can't wait to stay there again."
United States
John
The price is ₩145,406
₩163,865 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Homewood Suites by Hilton Santa Maria
Studio Suite, 2 Double Beds | Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Candlewood Suites Santa Maria by IHG

Candlewood Suites Santa Maria by IHG

Candlewood Suites Santa Maria by IHG
2.5 star property
3.3 km from Mission Hope Cancer Center
8.6 out of 10, Excellent, (1001)
"It was surprisingly great and the 2 girls during check inn were very professional and accomadating thank you"
United States
lupe
The price is ₩136,958
₩154,077 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Candlewood Suites Santa Maria by IHG
Check-in/check-out kiosk
Solaire Inn & Suites

Solaire Inn & Suites

Solaire Inn & Suites
2.5 star property
3.6 km from Mission Hope Cancer Center
8.2 out of 10, Very Good, (1001)
"Clean Staff very helpful "
United States
Sally
The price is ₩90,824
₩102,177 total
includes taxes & fees
Dec 28 - Dec 29
Solaire Inn & Suites
Pet-friendly amenities
Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North
2.0 star property
3.4 km from Mission Hope Cancer Center
7.6 out of 10, Good, (1012)
"Great staff and the room was clean"
Canada
Adam
The price is ₩79,300
₩89,439 total
includes taxes & fees
Dec 30 - Dec 31
Motel 6 Santa Maria, CA - North
Front of property - evening/night
Wine Stone Inn

Wine Stone Inn

Wine Stone Inn
5.0 star property
10.2 km from Mission Hope Cancer Center
9.8 out of 10, Exceptional, (600)
"Room was super clean and roomy ...bed was very comfortable! Love the decor in the entire hotel. Staff was friendly and accommodating. "
United States
shannon
The price is ₩206,302
₩245,499 total
includes taxes & fees
Dec 28 - Dec 29
Wine Stone Inn
Outdoor pool
Radisson Hotel Santa Maria

Radisson Hotel Santa Maria

Radisson Hotel Santa Maria
3.5 star property
6.8 km from Mission Hope Cancer Center
7.6 out of 10, Good, (1332)
"Staff was great . They were very welcoming made the stay comfortable "
United States
Luis
The price is ₩142,148
₩159,924 total
includes taxes & fees
Dec 28 - Dec 29
Radisson Hotel Santa Maria
Desk, free WiFi, bed sheets, wheelchair access
Colonial Motel

Colonial Motel

Colonial Motel
2.0 star property
3.4 km from Mission Hope Cancer Center
6.4 out of 10, (164)
"I recomendar this place "
United States
Everarda
The price is ₩108,125
₩121,640 total
includes taxes & fees
Dec 28 - Dec 29
Colonial Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mission Hope Cancer Center Hotel Reviews

Oxford Suites Pismo Beach

Oxford Suites Pismo Beach

10/10 Excellent
"Absolute perfection from beginning to end Free complimentary drinks , breakfast was outstanding. Next to the outlets . Hot tub . Rooms exceptional Price amazing .. "
Victoria 1-night trip
Posted 1 day ago
Oxford Suites Pismo Beach

Hotels near other Mission Hope Cancer Center attractions

Pacific Conservatory Theatre

You can get tickets for a performance at Pacific Conservatory Theatre during your stay in Santa Maria. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Simas Park

After visiting Simas Park, make a plan to see the other sights and activities in Santa Maria. While in this romantic area, you can savor the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Mission Hope Cancer Center?
Mission Hope Cancer Center is located in a family-friendly area of Santa Maria known for its array of dining options. If you're looking for a convenient place to stay, check out the 6 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Mission Hope Cancer Center?
Historic Santa Maria Inn is one of the top choices for your stay based on our traveler data, and this hotel offers 2 bars and a restaurant. It's located 1.4 mi (2.2 km) from Mission Hope Cancer Center. Another good option is Hampton Inn & Suites Santa Maria, located 2.3 mi (3.7 km) away.
How many hotels are there near Mission Hope Cancer Center?
Expedia has 6 hotels and other accommodations within a mile from Mission Hope Cancer Center.
If I need to cancel the hotel reservation for my stay near Mission Hope Cancer Center, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Mission Hope Cancer Center.
Where can I learn more about changing or cancelling my trip in the area near Mission Hope Cancer Center?
For more details about changing or cancelling your stay near Mission Hope Cancer Center, head over to our customer service page.
What can I see and do near Mission Hope Cancer Center?
Study the collections at Santa Maria Valley Historical Society, Natural History Museum, or Santa Maria Museum of Flight. You can enjoy live performances at Pacific Conservatory Theatre and Santa Maria Civic Theatre. Santa Maria Valley Discovery Museum, Rancho Bowl, and Santa Maria Fairpark are fun stops for the whole family while you're in town.