Find hotels in Panacea, FL from ₩139,514

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Dec 18 - Dec 19
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Dec 19 - Dec 20
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Dec 19 - Dec 21
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Dec 26 - Dec 28

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Our top choices for Panacea hotels

Comfort Studio | Terrace/patio
The Panacea Motel

The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (139)
Embrace coastal charm at this waterfront retreat offering complimentary WiFi and parking. Explore nearby Panacea Springs on hiking trails or kayak directly from the property. Woolley Park attractions are just minutes away.
"A v nice place to stay "
United States
Harry
The Panacea Motel
Lobby
The Lodge at Wakulla Springs

The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1004)
Set in Crawfordville, this hotel offers easy access to Wakulla Springs State Park and Wakulla State Forest. The Edward Ball Dining Room serves American cuisine, while amenities include free WiFi and parking. Guests appreciate the attentive staff and tranquil surroundings.
"Great stay. Boat tour was enjoyable. Quiet relaxing place"
United States
PATRICIA
The Lodge at Wakulla Springs
Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Premium bedding, desk, laptop workspace, blackout drapes
Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (946)
"Great hotel. Very good customer service and very clean"
United States
claudina
The price is ₩164,226
₩183,113 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Wakulla Inn & Suites
Daily cooked-to-order breakfast for a fee
St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (369)
Tee off at this coastal Carrabelle resort offering massages and dining at the restaurant. Enjoy the convenience of in-room washers/dryers and microwaves. Near St. James Bay Golf Club and Island View Park with free WiFi and parking.
"Very clean update villas"
United States
Jack
The price is ₩208,236
₩230,100 total
includes taxes & fees
Jan 1 - Jan 2, 2026
St James Bay Golf & Pickleball Resort
Interior entrance
Wildwood Inn

Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1001)
"Enjoyed our stay and would definitely stay again!"
United States
Corey
The price is ₩169,557
₩194,964 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Wildwood Inn
Terrace/patio
The Old Carrabelle Hotel

The Old Carrabelle Hotel

The Old Carrabelle Hotel
2.0 star property
Carrabelle
10.0 out of 10, Exceptional, (1)
The price is ₩200,852
₩221,941 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Old Carrabelle Hotel
Free WiFi, bed sheets
Franklin Inn

Franklin Inn

Franklin Inn
2.0 star property
Carrabelle
7.8 out of 10, Good, (456)
This motel offers clean rooms and a welcoming atmosphere near Carrabelle Beach and History Museum. Enjoy convenient amenities like free WiFi and parking, plus 24-hour front desk assistance for your coastal getaway.
"JJ was great great location clean room comfortable bed and good value. "
United States
Crystal
The price is ₩126,257
₩139,514 total
includes taxes & fees
Dec 21 - Dec 22
Franklin Inn
Terrace/patio
The Moorings Hotel and Marina

The Moorings Hotel and Marina

The Moorings Hotel and Marina
2.5 star property
Carrabelle
8.4 out of 10, Very Good, (39)
Waterfront hotel with its own marina where kayaking adventures begin. The outdoor pool offers refreshing breaks after exploring nearby Island View Park. Free WiFi and parking enhance your coastal getaway.
"Hotel was really nice and convenient to everything we wanted to do in the area. Very quiet and peaceful. Bed was a little uncomfortable, but that's a personal preference thing and I won't fault them for that. Really nice staff and easy check in and check out. Would definitely return!"
United States
Cheryl
The price is ₩203,814
₩225,215 total
includes taxes & fees
Dec 22 - Dec 23
The Moorings Hotel and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Panacea attractions

Alligator Point Beach

3.5/5 (2 reviews)
Why not spend a lazy afternoon at Alligator Point Beach during your trip to Alligator Point?
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Bald Point State Park

4.6/5 (9 reviews)
You can take time to visit Bald Point State Park during your travels to Alligator Point. Stroll along the beaches in this relaxing area, or seek out the fishing spots.
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Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

See all hotels in Panacea
Sunset over a lake at Panacea, northern Florida, USA | NONE |

Top Panacea Hotel Reviews

The Panacea Motel

The Panacea Motel

10/10 Excellent
"Excellent stay! Very clean and spacious room! Staff was friendly and helpful "
Teesha 2-night trip
Posted 2 weeks ago
The Panacea Motel

More cheap stays in Panacea

The Panacea Motel

The Panacea Motel

1545 Coastal Hwy Panacea FL
Get rates
9/10 Wonderful! (139 reviews)

Frequently asked questions

If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
Where can I learn more about changing or cancelling my trip to Panacea?
For more details about changing or cancelling your trip to Panacea, click here.
What's the best pet-friendly place to stay in Panacea?
The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What's the best hotel for staying near Tallahassee Regional Airport (TLH)?
Tallahassee Sun & Moon is one of the top choices for your stay and is a popular property, featuring free WiFi and free parking. It's located 3.5 mi (5.7 km) from Tallahassee Regional Airport. Other options close to the airport include Hampton Inn & Suites Tallahassee Capitol-University and Governors Inn.
What's it like to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 213 hotels and other accommodations to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Wilson Beach and Alligator Harbor Aquatic Preserve. Check out what more to see and do in Expedia's Panacea guide.
What's the seasonal weather like in Panacea?
The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.

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