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Find Resorts & Hotels with Spas in Southeast Missouri, MO
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Our top choices for Southeast Missouri hotels with a spa

1. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,002 reviews)
The price is ₩134,302
₩151,512 total
includes taxes & fees
Nov 15 - Nov 16

2. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,001 reviews)
The price is ₩126,243
₩145,147 total
includes taxes & fees
Nov 22 - Nov 23

3. Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (1,020 reviews)
The price is ₩119,226
₩133,504 total
includes taxes & fees
Dec 6 - Dec 7

4. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (978 reviews)
The price is ₩129,445
₩146,241 total
includes taxes & fees
Dec 6 - Dec 7

5. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (201 reviews)
The price is ₩114,544
₩130,367 total
includes taxes & fees
Nov 18 - Nov 19

6. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.4 out of 10, Exceptional, (118 reviews)
The price is ₩141,216
₩153,714 total
includes taxes & fees
Nov 15 - Nov 16

7. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
The price is ₩135,860
₩153,268 total
includes taxes & fees
Nov 19 - Nov 20

8. Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
9.6 out of 10, Exceptional, (85 reviews)
The price is ₩130,353
₩147,674 total
includes taxes & fees
Dec 10 - Dec 11

9. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.2 out of 10, Wonderful, (1,001 reviews)
The price is ₩96,693
₩109,084 total
includes taxes & fees
Nov 16 - Nov 17

10. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
8.8 out of 10, Excellent, (896 reviews)
The price is ₩107,318
₩116,145 total
includes taxes & fees
Nov 15 - Nov 16

11. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (860 reviews)
The price is ₩131,065
₩147,860 total
includes taxes & fees
Nov 22 - Nov 23

12. Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti CaruthersvilleHayti
9.2 out of 10, Wonderful, (1,001 reviews)
The price is ₩131,615
₩150,008 total
includes taxes & fees
Nov 22 - Nov 23

13. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (703 reviews)
The price is ₩153,522
₩173,195 total
includes taxes & fees
Nov 15 - Nov 16

14. Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.2 out of 10, Wonderful, (338 reviews)
The price is ₩165,610
₩180,895 total
includes taxes & fees
Nov 13 - Nov 14

15. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
The price is ₩126,907
₩144,437 total
includes taxes & fees
Dec 11 - Dec 12

16. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (559 reviews)
The price is ₩155,940
₩176,702 total
includes taxes & fees
Nov 22 - Nov 23

17. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (118 reviews)
The price is ₩147,747
₩168,025 total
includes taxes & fees
Nov 19 - Nov 20

18. Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
8.0 out of 10, Very good, (1,000 reviews)
The price is ₩83,409
₩93,396 total
includes taxes & fees
Nov 26 - Nov 27

19. Hampton Inn & Suites By Hilton Festus
Hampton Inn & Suites By Hilton FestusFestus
9.4 out of 10, Exceptional, (29 reviews)
The price is ₩152,261
₩174,110 total
includes taxes & fees
Nov 29 - Nov 30

20. The Atrium - A Boutique Hotel
The Atrium - A Boutique HotelPerryville
9.6 out of 10, Exceptional, (14 reviews)
The price is ₩117,823
₩134,879 total
includes taxes & fees
Dec 8 - Dec 9
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Cape Girardeau
10/10 Excellent


























































