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Check availability on Southeast Missouri Resorts & Hotels with Spas

Our top choices for Southeast Missouri hotels with a spa

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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
United States
Rex
The price is ₩139,993
₩157,932 total
includes taxes & fees
Feb 1 - Feb 2
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent
"Everything was wonderful "
STACEY 1-night trip
Posted 3 days ago
Drury Inn & Suites Hayti Caruthersville