Texas Medical Center Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to ₩234,741 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Find hotels in Downtown Houston

Texas Medical Center Hotel Deals

Blossom Hotel Houston

Blossom Hotel Houston

4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
The price is ₩192,939 per night from Jul 29 to Jul 30
₩192,939
₩225,738 total
Jul 29 - Jul 30
includes taxes & fees
9/10 Wonderful! (3,399 reviews)
"Very nice and quiet hotel"

Reviewed on Jul 16, 2025

Blossom Hotel Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
The price is ₩129,574 per night from Aug 3 to Aug 4
₩129,574
₩153,211 total
Aug 3 - Aug 4
includes taxes & fees
8.2/10 Very Good! (1,438 reviews)
Nice hotel in great shape
"Hotel was nice and clean. Service was prompt and efficient and the room was clean and well maintained."

Reviewed on Jul 16, 2025

Hilton Houston Plaza/Medical Center
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
The price is ₩161,152 per night from Jul 18 to Jul 19
₩161,152
₩189,545 total
Jul 18 - Jul 19
includes taxes & fees
9/10 Wonderful! (1,806 reviews)
Nice stay
"Room was clean and comfortable"

Reviewed on Jul 16, 2025

Hyatt Place Houston Medical Center
See all 6,467 properties in Texas Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Texas Medical Center vacation package cost?
Much less than you might think --- from only , in fact! By bundling flights, hotels and car rentals into a tailor-made vacation package, your getaway to Texas Medical Center is just a few clicks away.
How do I get a cheap travel package to Texas Medical Center?
Browse and lock in everything in the one place with our Texas Medical Center vacation packages. You'll discover bargains on flights, hotels, tours and more that'll keep your hip pocket happy and your adventurous spirit alive. And, with more than 550 airlines and 1,000,000 properties all over the world to select from, you'll have the flexibility to mix and match as you please.
Where should I stay in Texas Medical Center?
Choose a place close to Houston Zoo. This famous sight is in the middle of the action and on the must-see lists of many travelers.
What are the top hotels in Texas Medical Center?
Hilton Garden Inn Houston Medical Center, TX and Home2 Suites by Hilton Houston Medical Center, TX are two of the most well-known hotels in Texas Medical Center. Why not have a look at the rates and amenities at each and then decide?
How far in advance should I book my Texas Medical Center vacation?
Browse Expedia to compare international flights as soon as you know your travel dates. You can normally purchase a ticket up to a year in advance. If it's too early for your preferred air carrier, or you have to book last minute, don't stress. Low prices to Texas Medical Center occasionally appear just weeks before the date of departure.
What does an Expedia Texas Medical Center travel package include?
Expedia has all you need to lock in Texas Medical Center trip, but how your package is structured is your choice. Choose from a combination of rental cars, flights and hotels. In search of a few activities to keep you busy? Once you've made your booking, you can add them too. Whatever your style or budget, there's a package deal to match your needs.
What should I know before booking a Texas Medical Center travel package?
Our prices are already low. However, you'll snap up even more savings when you book your flights, hotels and car rentals together. With an Expedia travel package, you'll get transparent pricing and a terrific range of choice.
Can I choose my airline with a Texas Medical Center Expedia vacation package?
Yes --- and it's easy too. Expedia has access to more than 550 partner airlines around the world. Our packages give you the flexibility to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Texas Medical Center vacation package?
It's difficult to predict what tomorrow might bring, so it's good to know that you can change or cancel your Texas Medical Center vacation package. If you made your booking in the last 24 hours, you may be eligible for a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to learn more.

Discover the most popular places to visit in Texas Medical Center

NASA Johnson Space Center

NASA Johnson Space Center

4.5/5(1,214 reviews)

After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.

NASA Johnson Space Center
At the main entrance.

Toyota Center

4/5(967 reviews)

Catch an event at Toyota Center during your trip to Houston. Experience the acclaimed theater scene and entertainment choices in this vibrant area.

Toyota Center
Rice University

Rice University

4.5/5(356 reviews)

Enjoy the collegiate vibe around Rice University, a top university in Houston. Experience the area's fascinating museums and acclaimed art scene.

Rice University
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.