South Carolina Midlands Pet-friendly Vacations
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Top Pet-friendly South Carolina Midlands Hotels
La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
This pet-friendly hotel welcomes dogs and cats (fees apply).
7.8/10 Good! (1,680 reviews)
"Clean, easy check in, convenient"
Reviewed on Sep 14, 2025
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd, Columbia, SC
This pet-friendly hotel welcomes dogs and cats (fees apply).
7.4/10 Good! (1,012 reviews)
Worth it
"Staff was exceptionally polite and helpful"
Reviewed on Sep 20, 2025
Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr, Columbia, SC
Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.
9/10 Wonderful! (1,006 reviews)
"Best hotel we have stayed in a long time! Great room, quiet, good coffee and full breakfast! Fast check-in!"
Reviewed on Sep 20, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
