South Carolina Midlands Pet-friendly Vacations
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Top Pet-friendly South Carolina Midlands Hotels
La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St Florence SC
- 3 hours drive from Fort Jackson
This pet-friendly hotel welcomes dogs and cats (fees apply).
7.8/10 Good! (1,462 reviews)
"Close to the restaurants and shopping."
Reviewed on Oct 22, 2026
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
- 9 min drive from Fort Jackson
This pet-friendly hotel welcomes dogs and cats (fees apply).
8.4/10 Very Good! (1,005 reviews)
"This hotel is in a poor neighborhood and we feared for our safety. The hotel bed was amazing. The shower was nice! The AC was sketchy and the place had a smell! But the main issue for us was the lack of feeling safe. We stayed 3 nights and each night had people working on cars and sitting in lawn ..."
Reviewed on Oct 24, 2026
Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr Columbia SC
- 31 min drive from Fort Jackson
Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.
9.2/10 Wonderful! (1,001 reviews)
"Hotel is very close to I-26 exit 103, staff were personable and professional, and they serve a good breakfast."
Reviewed on Oct 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
