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Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC

3 hours drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.8/10 Good! (1,607 reviews)

If you cherish your sleep just a heads up for the train that goes through twice in middle of the night!

Reviewed on May 15, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

9 min drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

8/10 Very Good! (1,004 reviews)

We stayed for University of South Carolina graduation weekend. Even though it was a busy weekend, this newly remodeled property met our needs. The location was close to where we needed to be and they accommodated our two friendly well behaved dogs. The room was clean and had basic amenities but I ...

Reviewed on May 16, 2026

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC

31 min drive from Fort Jackson

Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.

9.2/10 Wonderful! (1,002 reviews)

The property was located on a lake with a walking path all around the lake. The pool area had a large beautiful pavilion with outdoor kitchen. The staff was friendly. The suite overlooking the lake was perfect for us.

Reviewed on May 15, 2026

See all 3,275 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.