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Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC

3 hours drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.8/10 Good! (1,595 reviews)

Every thing was great. Easy to get on and off 95

Reviewed on Apr 29, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

9 min drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

8/10 Very Good! (1,005 reviews)

The air conditioner in my room was a wall thermostat that was set at 75. When you tried to turn it down it went back to 75. Called front desk and he was clueless on what to do. It was so muggy it was miserable. For the price of two nights I would not stay again. I will say the rooms were very ...

Reviewed on May 1, 2026

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC

31 min drive from Fort Jackson

Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.

9.2/10 Wonderful! (1,001 reviews)

Great

Reviewed on Apr 20, 2026

See all 3,282 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.