Santo Spirito

Florence

A grand church interior with high vaulted ceilings, large columns, and a central altar.
A stone bridge over a calm river, with historic buildings on either side.
A bustling outdoor market with white tents and various stalls.
A church with a bell tower, a circular window, and a weather vane.
A cityscape with a river, a bridge, and mountains in the background.

Stay near popular Santo Spirito attractions

A town square with historic buildings, a church, and a bell tower.

Piazza Santo Spirito

9.6/10 (8 reviews)
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.
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Santo Spirito Hotel Deals

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
The price is ā‚©235,193 per night from Aug 19 to Aug 20
ā‚©235,193
ā‚©281,957 total
Aug 19 - Aug 20
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (696 reviews)
"The staff friendly, welcoming, and very helpful. Centrally located and the perfect spot to explore the city on foot. I will definitely return."

Reviewed on Jul 22, 2026

Hotel Horto Convento
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
The price is ā‚©141,327 per night from Aug 27 to Aug 28
ā‚©141,327
ā‚©178,705 total
Aug 27 - Aug 28
includes taxes & fees
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Piazza della Signoria ...
9/10 Wonderful! (285 reviews)
"Only thing good view and location"

Reviewed on Jul 30, 2026

La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
The price is ā‚©134,486 per night from Aug 2 to Aug 3
ā‚©134,486
ā‚©171,180 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,001 reviews)
"Great staff and well located especially for the West Bank of the city. Slightly too far out for the city etc"

Reviewed on May 12, 2026

UNA Hotels Vittoria Firenze
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI
The price is ā‚©108,692 per night from Aug 2 to Aug 3
ā‚©108,692
ā‚©139,485 total
Aug 2 - Aug 3
includes taxes & fees
Stay at this guesthouse in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (232 reviews)
"Conveniently located. Monica was super helpful. I would definitely stay there again."

Reviewed on Jul 20, 2026

Foresteria Valdese di Firenze - Casa per Ferie
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
The price is ā‚©210,985 per night from Aug 5 to Aug 6
ā‚©210,985
ā‚©255,253 total
Aug 5 - Aug 6
includes taxes & fees
Stay at this residence in Florence. Enjoy free WiFi, concierge services, and premium bedding. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (1,151 reviews)
"The apartment was 2 storey, amazing location. Had kitchen, fridge Perfect for families!! 10/10"

Reviewed on Jul 30, 2026

Palazzo Mannaioni Suites
Casa Santo Nome di GesĆ¹

Casa Santo Nome di GesĆ¹

Piazza del Carmine, 21 Florence FI
The price is ā‚©177,186 per night from Aug 1 to Aug 2
ā‚©177,186
ā‚©214,763 total
Aug 1 - Aug 2
includes taxes & fees
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (375 reviews)
"The location was perfect, quiet, directly of a lovely piazza! The hotel had a quiet garden, delicious breakfast and friendly staff!"

Reviewed on Jul 23, 2026

Casa Santo Nome di GesĆ¹
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito
A river with buildings on the right bank.

Historic Centre of Florence

Cathedral of Santa Maria del Fiore and Piazza della Signoria are a few top attractions in Historic Centre of Florence. Hop around the city on the metro at UnitĆ  Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop and check out the area's fascinating museums, stunning cathedral, and stunning river views.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Cathedral of Santa Maria del Fiore and Piazza del Duomo are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Signoria are top sights worth seeing.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

An ornate building with intricate architectural details and a clear blue sky in the background.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Santo Spirito