The Best Hotels Closest to Roswell Park Cancer Institute in Buffalo for 2026

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Our top choices for Roswell Park Cancer Institute hotels

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

A room with a textured ceiling, a chandelier, and walls painted in a two-tone color scheme.

A historic building with a prominent tower and a large entrance.

1. Buffalo Harmony House

Allentown, 1.2 km from Roswell Park Cancer Institute

Dustin

₩425,083

₩494,621 total

includes taxes & fees

Sep 6 - Sep 7

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A grand room with a chandelier, a fireplace, and ornate furniture.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

A room with a red patterned sofa, wooden bookshelves, a chandelier, and a traditional wooden coffee table.

2. InnBuffalo off Elmwood

Elmwood Village, 2.5 km from Roswell Park Cancer Institute

Terese

₩322,726

₩370,332 total

includes taxes & fees

Sep 30 - Oct 1

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A grand staircase with a wooden handrail and a leopard print carpet, leading to a room with a large window and a door with frosted glass panels.

A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.

A living room with a fireplace, two leather armchairs, a coffee table, and a chandelier.

3. The Edward Hotel

Elmwood Village, 2.3 km from Roswell Park Cancer Institute

Lynne

₩191,311

₩263,432 total

includes taxes & fees

Sep 2 - Sep 3

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A pool table in a room with dark walls, large windows, and green upholstered chairs.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.

4. The Mansion On Delaware Ave

Allentown, 0.8 km from Roswell Park Cancer Institute

Jennifer Penfield

₩283,664

₩325,504 total

includes taxes & fees

Sep 2 - Sep 3

A two-story building with a white exterior, a red door, and large windows.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

A hot tub with a wooden fence and a brick building in the background.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

5. Buffalo Guesthouse

Allentown, 0.5 km from Roswell Park Cancer Institute

Robert

₩237,962

₩273,062 total

includes taxes & fees

Sep 3 - Sep 4

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

A circular fire pit with a metal railing, surrounded by a stone base, set on a tiled patio with a city skyline in the background.

A modern bar area with a curved counter, leather bar stools, and a large chandelier.

A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

6. Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Mike

₩336,498

₩392,861 total

includes taxes & fees

Sep 3 - Sep 4

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

A modern hotel lobby with a reception desk, seating area, and a large window offering a view of the city.

A spacious bedroom with a large bed, a comfortable armchair, and a view of a body of water through floor-to-ceiling windows.

A hotel lobby with a seating area, dining tables, and large windows offering views of the cityscape.

7. Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 2.6 km from Roswell Park Cancer Institute

Vincent

₩331,096

₩386,554 total

includes taxes & fees

Sep 7 - Sep 8

A spacious lobby with modern furniture, large windows, and a high ceiling with exposed beams.

A spacious lobby with a stone fireplace, comfortable seating, large windows, and a modern design.

An outdoor patio area with seating, a fire feature, and a glass-enclosed space with greenery.

A gym with treadmills and a rowing machine, large windows, and a city view.

8. The Westin Buffalo

Buffalo Theater District, 1.2 km from Roswell Park Cancer Institute

Jamie

₩371,987

₩434,294 total

includes taxes & fees

Sep 6 - Sep 7

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.

9. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 0.2 km from Roswell Park Cancer Institute

EDWARD

₩203,171

₩237,202 total

includes taxes & fees

Sep 7 - Sep 8

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.

A modern lobby with a seating area, a fireplace, and a large window offering a view of the city.

A modern lobby with a wooden reception desk, comfortable seating, and a decorative wall with shelves.

10. Courtyard Buffalo Downtown / Canalside

Downtown Buffalo, 2.4 km from Roswell Park Cancer Institute

Diana

₩231,330

₩270,077 total

includes taxes & fees

Sep 6 - Sep 7

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A hotel lobby with a curved reception desk, a chandelier, a seating area with leather chairs, and a tiled floor.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

A modern kitchen with a central island, bar stools, and various appliances.

11. Best Western on the Avenue

Allentown, 0.7 km from Roswell Park Cancer Institute

Emily

₩195,717

₩228,500 total

includes taxes & fees

Sep 7 - Sep 8

A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

A hotel room with a sofa, a desk, a chair, a television, and a large mirror.

An indoor swimming pool with clear blue water, a metal pool ladder, and a seating area with tables and chairs.

A breakfast buffet with various pastries, fruits, and bread.

12. Hampton Inn & Suites Buffalo Downtown

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Yegana

₩211,951

₩247,453 total

includes taxes & fees

Sep 7 - Sep 8

An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.

A modern lobby with a leather sofa, a fireplace, and a television mounted on the wall.

A hotel room with a bed, a desk, a chair, and a view of a cityscape through large windows.

The exterior of the Hilton Garden Inn, featuring a prominent entrance with a large sign, a flag, and a well-maintained sidewalk.

13. Hilton Garden Inn Buffalo Downtown

Buffalo Theater District, 1.5 km from Roswell Park Cancer Institute

Steve

₩188,401

₩224,745 total

includes taxes & fees

Sep 9 - Sep 10

A dining area with a wooden table and chairs, a fireplace, and large windows with a view of greenery outside.

A traditional living room with a wooden floor, a sofa, a coffee table, and a fireplace.

A grand staircase with a decorative railing and a Christmas tree adorned with ornaments and ribbons.

A casino interior with slot machines, a large illuminated pillar, and comfortable seating areas.

14. Summer Street Guest House

Bryant, 1.3 km from Roswell Park Cancer Institute

Anthony

₩491,105

₩720,475 total

includes taxes & fees

Sep 2 - Sep 3

A lobby with a staircase, seating area, and a view of the outdoors.

A bathroom with a toilet, sink, and shower curtain.

A hotel room with two beds, a desk, a television, and a window.

A hotel with a classic brick facade, a glass entrance, and flags.

15. Lenox Hotel and Suites

Allentown, 0.8 km from Roswell Park Cancer Institute

Dereck

₩144,008

₩165,250 total

includes taxes & fees

Sep 13 - Sep 14

A long, ornate hallway with marble walls and a patterned floor, leading to a set of double doors.

The facade of Hotel at the Lafayette with a classic architectural style, large windows, and a prominent entrance.

A spacious indoor area with wooden flooring, multiple tables and chairs, a central bar area, and large windows allowing natural light.

A spacious lobby with a central seating area, large columns, and a chandelier.

16. Hotel at the Lafayette Trademark Collection by Wyndham

Buffalo Theater District, 1.6 km from Roswell Park Cancer Institute

Hannah

₩173,207

₩202,219 total

includes taxes & fees

Sep 7 - Sep 8

An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

A hotel room with a sofa set, a small coffee table, a TV, and a lamp.

A restaurant with multiple tables and chairs, large windows with curtains, and a chandelier.

A Hyatt Regency hotel with a large entrance, a statue of a bull, and a landscaped garden with various plants.

17. Hyatt Regency Buffalo / Hotel and Conference Center

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Melanie

₩188,469

₩220,037 total

includes taxes & fees

Sep 20 - Sep 21

A dining area with a wooden table set for four, surrounded by chairs. There is a kitchen area with cabinets and appliances in the background.

A kitchen with wooden cabinets, a dishwasher, and a dining area with a table and chairs.

A bedroom with a bed, bedside lamps, a nightstand, a window with curtains, and wall art.

A kitchen with wooden cabinets, stainless steel appliances, and a red toaster.

18. 4 Mi to Dtwn: Family Home in Buffalo

Masten Park, 1.6 km from Roswell Park Cancer Institute

₩406,177

₩719,494 total

includes taxes & fees

Sep 7 - Sep 8

A buffet setup with various food items and utensils.

A hotel reception desk with a large mirror, a chandelier, and a 'HOTEL' sign.

A building with a large illuminated sign reading "Russells STEAKS - CHOPS - AND MORE".

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

19. Salvatores Grand Hotel

15.2 km from Roswell Park Cancer Institute

Carol

₩196,456

₩223,466 total

includes taxes & fees

Sep 2 - Sep 3

A hotel with a prominent entrance, a clock tower, and the name "REIKART HOUSE" displayed above the entrance.

A spacious dining area with high ceilings, large windows, and modern chandeliers.

A spacious living area with a fireplace, a large sofa, and a dining area with a table and chairs.

20. Reikart House, Buffalo, a Tribute Portfolio Hotel

10.4 km from Roswell Park Cancer Institute

Brandon

₩318,651

₩362,467 total

includes taxes & fees

Sep 7 - Sep 8

View all properties

Compare popular hotels close to Roswell Park Cancer Institute

Property	Property class	Guest rating
Buffalo Harmony House	10.0 Exceptional 53 reviews	View
InnBuffalo off Elmwood	10.0 Exceptional 224 reviews	View
The Edward Hotel	9.6 Exceptional 257 reviews	View
The Mansion On Delaware Ave	9.4 Exceptional 1,002 reviews	View
Buffalo Guesthouse	9.4 Exceptional 197 reviews	View

Top Roswell Park Cancer Institute Hotel Reviews

The Mansion On Delaware Ave

10/10 Excellent

"The room was nicely styled and clean. The staff were kind."

Aloft by Marriott Buffalo Downtown

10/10 Excellent

"Excellent customer service"

Residence Inn by Marriott Buffalo Downtown

10/10 Excellent

"Property is very modern and well maintained. Rooms are very nice."

Embassy Suites Buffalo

8/10 Good

"The experience was good. I would just expect a little more from a newly renovated hotel attempting to renew their image. (Front desk, consider adding room service, valet was hard to find as they were sitting down behind a corner away from their station). I’m fine with it, but details do matter."

Best Western on the Avenue

10/10 Excellent

"Everything was perfect"

Hilton Garden Inn Buffalo Downtown

8/10 Good

"Staff was wonderful. They were very helpful about the area restaurants and things to see. We stayed on floor 8. The floor is definitely in need of some new carpet. The location of the hotel is very well situated for things to do in Buffalo."

Summer Street Guest House

10/10 Excellent

"Loved the house, the owner, and his dog!"

Buffalo Harmony House

10/10 Excellent

"The breakfast was incredible, the room was cute and the staff was attentive! The only thing that would have made it better was if I could have stayed longer!"

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

8.2/10 (144 reviews)

You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your trip to Buffalo. Experience the area's great live music and entertainment choices.

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Studio Arena Theater

Enjoy a performance at Studio Arena Theater, a storied theater in Buffalo. Experience the area's acclaimed theater scene and entertainment choices.

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Shea's 710 Theatre

You can enjoy a show at Shea's 710 Theatre during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Town Ballroom

You can make plans for a show at Town Ballroom during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Trinity Episcopal Church

You can learn about the history of Buffalo with a stop at Trinity Episcopal Church. Experience the entertainment choices or attend a sporting event in this family-friendly area.

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Alleyway Theatre

You can make plans for a show at Alleyway Theatre during your stay in Buffalo. Experience the great live music and entertainment choices in this family-friendly area.

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The 9th Ward

You can make plans for a show at The 9th Ward during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Asbury Hall at Babeville

You can make plans for a show at Asbury Hall at Babeville during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Frequently asked questions

What's the area like around Roswell Park Cancer Institute?

Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 63 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Roswell Park Cancer Institute?

Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find near Roswell Park Cancer Institute?

Expedia has 63 hotels and other accommodations within a mile from Roswell Park Cancer Institute.

If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near Roswell Park Cancer Institute.

Where can I learn more about changing or cancelling my trip in the area near Roswell Park Cancer Institute?

For more details about changing or cancelling your stay near Roswell Park Cancer Institute, click here.

What can I see and do near Roswell Park Cancer Institute?

You might want to spend some time browsing the exhibits at Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park, or Buffalo AKG Art Museum. Statler Tower, Buffalo Central Terminal, and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Kleinhans Music Hall, Town Ballroom, and Buffalo Iron Works.

How can I get to Roswell Park Cancer Institute?

With so many transportation options, seeing all of the area near Roswell Park Cancer Institute is easy. Take advantage of metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.

Find hotels near Roswell Park Cancer Institute, Buffalo from ₩165,250

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Treat yourself

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Our top choices for Roswell Park Cancer Institute hotels

1. Buffalo Harmony House

2. InnBuffalo off Elmwood

3. The Edward Hotel

4. The Mansion On Delaware Ave

5. Buffalo Guesthouse

6. Curtiss Hotel, an Ascend Collection Hotel

7. Buffalo Marriott at LECOM HARBORCENTER

8. The Westin Buffalo

9. Wyndham Garden Buffalo Downtown

10. Courtyard Buffalo Downtown / Canalside

11. Best Western on the Avenue

12. Hampton Inn & Suites Buffalo Downtown

13. Hilton Garden Inn Buffalo Downtown

14. Summer Street Guest House

15. Lenox Hotel and Suites

16. Hotel at the Lafayette Trademark Collection by Wyndham

17. Hyatt Regency Buffalo / Hotel and Conference Center

18. 4 Mi to Dtwn: Family Home in Buffalo

19. Salvatores Grand Hotel

20. Reikart House, Buffalo, a Tribute Portfolio Hotel

Compare popular hotels close to Roswell Park Cancer Institute

Top Roswell Park Cancer Institute Hotel Reviews

The Mansion On Delaware Ave

Aloft by Marriott Buffalo Downtown

Residence Inn by Marriott Buffalo Downtown

Embassy Suites Buffalo

Best Western on the Avenue

Hilton Garden Inn Buffalo Downtown

Summer Street Guest House

Buffalo Harmony House

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

Studio Arena Theater

Shea's 710 Theatre

Town Ballroom

Trinity Episcopal Church

Alleyway Theatre

The 9th Ward

Asbury Hall at Babeville

Frequently asked questions