The Best Hotels Closest to Roswell Park Cancer Institute in Buffalo for 2026

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Our top choices for Roswell Park Cancer Institute hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A room with a red patterned sofa, wooden bookshelves, a chandelier, and a traditional wooden coffee table.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

A large, two-story building with a prominent entrance, multiple windows, and a well-maintained garden.

1. InnBuffalo off Elmwood

Elmwood Village, 2.5 km from Roswell Park Cancer Institute

Terese

₩178,728

₩205,092 total

includes taxes & fees

Nov 9 - Nov 10

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

A room with a textured ceiling, a chandelier, and walls painted in a two-tone color scheme.

A grand hallway with a wooden staircase, a chandelier, and a patterned floor.

2. Buffalo Harmony House

Allentown, 1.2 km from Roswell Park Cancer Institute

John

₩436,741

₩507,866 total

includes taxes & fees

Oct 25 - Oct 26

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.

A grand staircase with a wooden handrail and a leopard print carpet, leading to a room with a large window and a door with frosted glass panels.

A bedroom with a four-poster bed, a yellow sofa, a white coffee table, and a desk with a chair.

3. The Edward Hotel

Elmwood Village, 2.3 km from Roswell Park Cancer Institute

Grace

₩172,989

₩238,207 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

A spacious bedroom with a large bed, a comfortable armchair, and a view of a body of water through floor-to-ceiling windows.

A modern kitchen with a central island, bar stools, and built-in appliances.

A hotel lobby with a seating area, dining tables, and large windows offering views of the cityscape.

4. Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 2.6 km from Roswell Park Cancer Institute

James

₩336,725

₩393,126 total

includes taxes & fees

Nov 15 - Nov 16

A two-story building with a white exterior, a red door, and large windows.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

A living room with a fireplace, a chandelier, leather sofas, and a glass coffee table.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

5. Buffalo Guesthouse

Allentown, 0.5 km from Roswell Park Cancer Institute

Jan

₩233,334

₩267,750 total

includes taxes & fees

Oct 17 - Oct 18

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

A modern bar area with a curved counter, leather bar stools, and a large chandelier.

6. Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

John

₩340,815

₩397,901 total

includes taxes & fees

Nov 15 - Nov 16

A pool table in a room with dark walls, large windows, and green upholstered chairs.

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

7. The Mansion On Delaware Ave

Allentown, 0.8 km from Roswell Park Cancer Institute

Marilyn

₩264,311

₩303,297 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A modern lobby with a sofa set, coffee table, potted plants, and a large window providing natural light.

A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

8. Wyndham Garden Buffalo Downtown

Downtown Buffalo, 0.2 km from Roswell Park Cancer Institute

Julian

₩204,033

₩238,210 total

includes taxes & fees

Nov 15 - Nov 16

A spacious lobby with modern furniture, large windows, and a high ceiling with exposed beams.

A spacious lobby with a stone fireplace, comfortable seating, large windows, and a modern design.

The Westin hotel entrance with a glass facade and a sign indicating it's now open.

A gym with treadmills and a rowing machine, large windows, and a city view.

9. The Westin Buffalo

Buffalo Theater District, 1.2 km from Roswell Park Cancer Institute

Sarah

₩341,033

₩398,155 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a bar area, seating, and a large TV screen.

A modern building with a Starbucks on the ground floor, featuring large windows and a flat roof.

A modern restaurant with a long counter, bar stools, and a refrigerated display.

A modern indoor swimming pool with clear blue water, surrounded by lounge chairs and a glass-enclosed area.

10. Residence Inn by Marriott Buffalo Downtown

Allentown, 0.7 km from Roswell Park Cancer Institute

Karen

₩318,018

₩371,287 total

includes taxes & fees

Nov 8 - Nov 9

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

A modern lobby with a wooden reception desk, comfortable seating, and a decorative wall with shelves.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered walkway and a courtyard.

A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.

11. Courtyard Buffalo Downtown / Canalside

Downtown Buffalo, 2.4 km from Roswell Park Cancer Institute

Diana

₩272,424

₩318,055 total

includes taxes & fees

Nov 8 - Nov 9

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A modern kitchen with a central island, bar stools, and various appliances.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

A hotel lobby with a curved reception desk, a chandelier, a seating area with leather chairs, and a tiled floor.

12. Best Western on the Avenue

Allentown, 0.7 km from Roswell Park Cancer Institute

John

₩203,980

₩238,146 total

includes taxes & fees

Nov 3 - Nov 4

A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

A breakfast buffet with various pastries, fruits, and bread.

An indoor swimming pool with clear blue water, a metal pool ladder, and a seating area with tables and chairs.

A hotel room with a sofa, a desk, a chair, a television, and a large mirror.

13. Hampton Inn & Suites Buffalo Downtown

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Gerald D

₩226,830

₩264,825 total

includes taxes & fees

Nov 15 - Nov 16

An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.

The exterior of the Hilton Garden Inn, featuring a prominent entrance with a large sign, a flag, and a well-maintained sidewalk.

A modern lobby with a leather sofa, a fireplace, and a television mounted on the wall.

A lobby area with a reception desk, seating arrangements, a coffee station with beverages and snacks, and a decorative wall with a fireplace.

14. Hilton Garden Inn Buffalo Downtown

Buffalo Theater District, 1.5 km from Roswell Park Cancer Institute

Mercedes

₩210,872

₩246,193 total

includes taxes & fees

Nov 16 - Nov 17

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers.

A gym with exercise equipment, a mirror, and a television.

A modern hotel room with a wooden dresser, a flat-screen TV, a kitchenette, a blue sofa, and a small table.

15. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 1.1 km from Roswell Park Cancer Institute

Charles

₩158,238

₩184,742 total

includes taxes & fees

Nov 16 - Nov 17

A long, ornate hallway with marble walls and a patterned floor, leading to a set of double doors.

A spacious lobby with a central seating area, large columns, and a chandelier.

The facade of Hotel at the Lafayette with a classic architectural style, large windows, and a prominent entrance.

A spacious indoor area with wooden flooring, multiple tables and chairs, a central bar area, and large windows allowing natural light.

16. Hotel at the Lafayette Trademark Collection by Wyndham

Buffalo Theater District, 1.6 km from Roswell Park Cancer Institute

Thomas

₩186,935

₩218,246 total

includes taxes & fees

Nov 16 - Nov 17

An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

A restaurant with multiple tables and chairs, large windows with curtains, and a chandelier.

A hotel room with a sofa set, a small coffee table, a TV, and a lamp.

A Starbucks coffee shop with a modern design, featuring wooden furniture and a spacious layout.

17. Hyatt Regency Buffalo / Hotel and Conference Center

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Joseph

₩204,284

₩238,501 total

includes taxes & fees

Oct 25 - Oct 26

A lobby with a staircase, seating area, and a view of the outdoors.

A reception area with a marble wall, a reception desk with glass panels, a clock, and a television mounted on the wall.

A hotel room with two beds, a desk, a television, and a window.

A hotel with a classic brick facade, a glass entrance, and flags.

18. Lenox Hotel and Suites

Allentown, 0.8 km from Roswell Park Cancer Institute

Thomas

₩149,646

₩171,718 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.

A modern bar area with seating, a counter with bottles, and a large window.

A conference room with two chairs and a table, large windows with a city view, and a patterned carpet.

A modern hotel room with a dining area, a large bed, and a view of the city.

19. Embassy Suites Buffalo

Buffalo Theater District, 1.3 km from Roswell Park Cancer Institute

Michelle

₩238,229

₩278,133 total

includes taxes & fees

Nov 15 - Nov 16

A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

A modern cafe with round tables and chairs, a bar area, and a neon sign.

A modern hotel with a glass facade, multiple floors, and a prominent 'Aloft' sign.

A bar area with a circular bar counter, multiple hanging light fixtures, and bar stools.

20. Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 0.8 km from Roswell Park Cancer Institute

Anthony T

₩267,127

₩311,871 total

includes taxes & fees

Nov 15 - Nov 16

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Compare popular hotels close to Roswell Park Cancer Institute

Property	Property class	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 224 reviews	View
Buffalo Harmony House	10.0 Exceptional 56 reviews	View
The Edward Hotel	9.6 Exceptional 268 reviews	View
Buffalo Marriott at LECOM HARBORCENTER	9.4 Exceptional 986 reviews	View
Buffalo Guesthouse	9.4 Exceptional 221 reviews	View

Top Roswell Park Cancer Institute Hotel Reviews

Wyndham Garden Buffalo Downtown

10/10 Excellent

"Parking with valet worked great. Shuttle to restaurants was awesome."

Hilton Garden Inn Buffalo Downtown

8/10 Good

"Staff were helpful. Restaurant on site important since many local restaurants close at 6 PM."

Hampton Inn & Suites Buffalo Downtown

10/10 Excellent

"Convenient"

Hotel at the Lafayette Trademark Collection by Wyndham

10/10 Excellent

"Good charming property in central Buffalo"

Lenox Hotel and Suites

10/10 Excellent

"The Lenox is a lovely hotel with lots of character. It centrally located so you can walk to Allentown and take in Millionaires row on Delaware Ave. The staff were helpful and friendly. Buffalo is a gem and stating at the Lenox was perfect. I highly recommend."

Residence Inn by Marriott Buffalo Downtown

10/10 Excellent

"Clean room. Breakfast good."

Buffalo Guesthouse

10/10 Excellent

"Comfy beds and friendly environment."

The Westin Buffalo

10/10 Excellent

"."

Summer Street Guest House

10/10 Excellent

"Loved the house, the owner, and his dog!"

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

8.2/10 (144 reviews)

You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theater scene.

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Studio Arena Theater

Enjoy a performance at Studio Arena Theater, a storied theater in Buffalo. Experience the area's great live music and entertainment choices.

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Shea's 710 Theatre

You can enjoy a show at Shea's 710 Theatre during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Town Ballroom

You can make plans for a show at Town Ballroom during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Trinity Episcopal Church

You can learn about the history of Buffalo with a stop at Trinity Episcopal Church. Experience the great live music or attend a sporting event in this family-friendly area.

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Alleyway Theatre

You can make plans for a show at Alleyway Theatre during your stay in Buffalo. Experience the acclaimed theater scene and great live music in this family-friendly area.

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The 9th Ward

You can make plans for a show at The 9th Ward during your trip to Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Asbury Hall at Babeville

You can make plans for a show at Asbury Hall at Babeville during your stay in Buffalo. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Frequently asked questions

What's the area like around Roswell Park Cancer Institute?

Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 71 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Roswell Park Cancer Institute?

Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find near Roswell Park Cancer Institute?

Expedia has 71 hotels and other accommodations within a mile from Roswell Park Cancer Institute.

If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near Roswell Park Cancer Institute.

Where can I learn more about changing or cancelling my trip in the area near Roswell Park Cancer Institute?

For more details about changing or cancelling your stay near Roswell Park Cancer Institute, click here.

What can I see and do near Roswell Park Cancer Institute?

You might want to spend some time browsing the exhibits at Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park, or Buffalo AKG Art Museum. Statler Tower, Buffalo Central Terminal, and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Kleinhans Music Hall, Town Ballroom, and Road Less Traveled Productions.

How can I get to Roswell Park Cancer Institute?

With so many transportation options, seeing all of the area near Roswell Park Cancer Institute is easy. Take advantage of metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.

Find hotels near Roswell Park Cancer Institute, Buffalo from ₩171,718

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Our top choices for Roswell Park Cancer Institute hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. Buffalo Marriott at LECOM HARBORCENTER

5. Buffalo Guesthouse

6. Curtiss Hotel, an Ascend Collection Hotel

7. The Mansion On Delaware Ave

8. Wyndham Garden Buffalo Downtown

9. The Westin Buffalo

10. Residence Inn by Marriott Buffalo Downtown

11. Courtyard Buffalo Downtown / Canalside

12. Best Western on the Avenue

13. Hampton Inn & Suites Buffalo Downtown

14. Hilton Garden Inn Buffalo Downtown

15. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

16. Hotel at the Lafayette Trademark Collection by Wyndham

17. Hyatt Regency Buffalo / Hotel and Conference Center

18. Lenox Hotel and Suites

19. Embassy Suites Buffalo

20. Aloft by Marriott Buffalo Downtown

Compare popular hotels close to Roswell Park Cancer Institute

Top Roswell Park Cancer Institute Hotel Reviews

Wyndham Garden Buffalo Downtown

Hilton Garden Inn Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

Hotel at the Lafayette Trademark Collection by Wyndham

Lenox Hotel and Suites

Residence Inn by Marriott Buffalo Downtown

Buffalo Guesthouse

The Westin Buffalo

Summer Street Guest House

Other attractions near Roswell Park Cancer Institute

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

Studio Arena Theater

Shea's 710 Theatre

Town Ballroom

Trinity Episcopal Church

Alleyway Theatre

The 9th Ward

Asbury Hall at Babeville

Frequently asked questions