Find hotels in Downtown South San Francisco, San Francisco from ₩108,265

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Discover 4,684 Downtown South San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
Downtown South San Francisco
8.0 out of 10, Very Good, (2003)
"Hotel was good for the price. "
United States
Dominique
The price is ₩147,061
₩172,751 total
includes taxes & fees
Nov 24 - Nov 25
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (969)
"This place exceeded my expectations. Super easy and convenient garage parking and lovely accommodations and friendly staff. I will definitely stay here again when in the area on business."
United States
Rachel
The price is ₩143,935
₩168,797 total
includes taxes & fees
Nov 27 - Nov 28
Airport Inn

Inn By The SFO

2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1000)
"we booked a room when we get there they said no room available even we paid in advance. their reason overbooked."
Canada
Krystyl Kim
Inn By The SFO

Miller Apartments

2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (15)
"I like that there's a kitchen to use!"
United States
Rogelio
The price is ₩90,868
₩216,348 total
includes taxes & fees
Nov 27 - Nov 28
Miller Apartments

Holiday Inn Express and Suites Fisherman's Wharf by IHG

3.0 star property
16.6 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2182)
"Rooms were quiet and clean, super friendly staff, lots of seating at breakfast, great location, hotel in good condition, water, coffee and tea anytime. Would stay again."
United States
Laura
The price is ₩200,637
₩279,757 total
includes taxes & fees
Dec 12 - Dec 13
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Harbor View Inn

2.0 star property
17.7 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (602)
"Clean room, great views, and perfect location!"
United States
Christina
The price is ₩171,777
₩215,160 total
includes taxes & fees
Nov 24 - Nov 25
Harbor View Inn

Holiday Inn Golden Gateway by IHG

3.5 star property
14.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (4822)
"Easy checkin, clean, friendly staff."
United States
Deja
The price is ₩173,013
₩203,632 total
includes taxes & fees
Nov 24 - Nov 25
Holiday Inn Golden Gateway by IHG

Inn at Rockaway San Francisco Pacifica

2.5 star property
8.8 km from Downtown South San Francisco
8.2 out of 10, Very Good, (1005)
"Great Staff, great view. Walkable small town with neat things going on...farmers' market, wine bar, good restaurant"
United States
Stephen
Inn at Rockaway San Francisco Pacifica

Half Moon Bay Lodge

3.0 star property
24.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1056)
"Great hotel"
United States
Brian
The price is ₩176,909
₩208,025 total
includes taxes & fees
Dec 15 - Dec 16
Half Moon Bay Lodge

DoubleTree by Hilton Hotel Berkeley Marina

4.0 star property
25.3 km from Downtown South San Francisco
8.2 out of 10, Very Good, (3743)
"We loved our stay at this hotel!"
United States
Mollie
The price is ₩202,527
₩233,300 total
includes taxes & fees
Nov 24 - Nov 25
DoubleTree by Hilton Hotel Berkeley Marina

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
16.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (7084)
"Room was clean and spacious, massive bed, breakfast was very good, perfect location! "
United Kingdom
miss h
The price is ₩158,717
₩246,702 total
includes taxes & fees
Dec 2 - Dec 3
Hotel Riu Plaza Fisherman's Wharf

Hyatt Centric Fisherman's Wharf San Francisco

4.0 star property
16.6 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1475)
"Super location easy walking to all the tourist locations Great food and hospitality services "
United States
Melissa
The price is ₩202,091
₩297,737 total
includes taxes & fees
Nov 23 - Nov 24
Hyatt Centric Fisherman's Wharf San Francisco

Hotel Caza Fisherman's Wharf

4.0 star property
16.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (3828)
"Great place to stay"
United States
Joseph
The price is ₩172,755
₩270,836 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Caza Fisherman's Wharf

FOUND Hotel Carlton, Nob Hill

2.0 star property
14.6 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1038)
"Courteous staff, clean room, and comfortable bed."
United States
Thomas
The price is ₩91,987
₩108,265 total
includes taxes & fees
Dec 2 - Dec 3
FOUND Hotel Carlton, Nob Hill

Hilton Garden Inn San Francisco Arpt North

3.0 star property
The East Side, 1.6 km from Downtown South San Francisco
8.4 out of 10, Very Good, (1006)
"Good stay"
United States
Mary Grace
The price is ₩132,594
₩156,046 total
includes taxes & fees
Nov 23 - Nov 24
Hilton Garden Inn San Francisco Arpt North

Hotel Majestic

3.5 star property
14.5 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1011)
"Beautiful historic hotel."
United States
ramanujam
The price is ₩197,845
₩230,505 total
includes taxes & fees
Nov 23 - Nov 24
Hotel Majestic

The Lodge at Tiburon

3.5 star property
24.5 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1001)
"Great location, beautiful town"
United States
Erez
The price is ₩261,322
₩333,973 total
includes taxes & fees
Dec 7 - Dec 8
The Lodge at Tiburon

Hyatt Regency San Francisco Airport

4.0 star property
8.4 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1340)
"Clean room, staff"
United States
Kaoru
The price is ₩231,169
₩303,544 total
includes taxes & fees
Nov 24 - Nov 25
Hyatt Regency San Francisco Airport

Hilton San Francisco Airport Bayfront

4.0 star property
9.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2653)
"Clean room, comfortable bed, airport shuttle and excellent restaurant! "
United States
patricia
The price is ₩138,336
₩157,281 total
includes taxes & fees
Dec 14 - Dec 15
Hilton San Francisco Airport Bayfront

HYATT house Emeryville/San Francisco Bay Area

3.0 star property
23 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1162)
"Check in was great and the staff was helpful and courteous. "
United States
Geraldine
The price is ₩245,707
₩275,672 total
includes taxes & fees
Dec 14 - Dec 15
HYATT house Emeryville/San Francisco Bay Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Downtown South San Francisco Hotel Reviews

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Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood.
What's a favorite place to stay in Downtown South San Francisco?
Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favorite options in the area include Airport Inn and Inn By The SFO.
How many hotels will I find in the Downtown South San Francisco area?
When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodations in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco.
Where can I learn more about changing or cancelling my trip to Downtown South San Francisco?
To find more details about picking new dates or cancelling your trip to Downtown South San Francisco, head over to our customer service page.
What can I see and do in this South San Francisco neighborhood?
See's Candies, Cinemark Century at Tanforan, and K1 Speed are just a few of the places to visit in and around Downtown South San Francisco. K1 Speed San Francisco and The Shops at Tanforan are also worth a visit when you're out sightseeing in South San Francisco.