Find hotels in Downtown South San Francisco, San Francisco from ₩140,439

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 28 - Sep 29
Tomorrow
Sep 29 - Sep 30
Next weekend
Oct 3 - Oct 5
In two weeks
Oct 10 - Oct 12

Filter by

Guest rating
Guest rating
Star rating

Discover 4,606 Downtown South San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Exterior

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
8.0 out of 10, Very Good, (2038)
"Great place to stay "
The price is ₩152,178
₩178,500 total
includes taxes & fees
Oct 26 - Oct 27
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Airport Inn
Interior detail

Airport Inn

2.0 star property
8.8 out of 10, Excellent, (959)
"The inside is super nice and clean. Very pleasant"
The price is ₩145,905
₩170,956 total
includes taxes & fees
Sep 29 - Sep 30
Airport Inn
Inn By The SFO
Lobby

Inn By The SFO

2.0 star property
7.8 out of 10, Good, (1000)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
The price is ₩124,209
₩146,054 total
includes taxes & fees
Oct 6 - Oct 7
Inn By The SFO
Miller Apartments
Fridge, microwave, coffee/tea maker, dining tables

Miller Apartments

2.0 star property
7.8 out of 10, Good, (14)
"Ty"
The price is ₩88,107
₩209,773 total
includes taxes & fees
Sep 29 - Sep 30
Miller Apartments
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Free daily buffet breakfast

Holiday Inn Express and Suites Fisherman's Wharf by IHG

3.0 star property
9.2 out of 10, Wonderful, (2177)
"Good place to stay!"
The price is ₩194,540
₩271,270 total
includes taxes & fees
Oct 19 - Oct 20
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Hotel North Beach
Lobby

Hotel North Beach

2.0 star property
7.0 out of 10, Good, (1010)
"Good location "
The price is ₩81,552
₩95,824 total
includes taxes & fees
Sep 29 - Sep 30
Hotel North Beach
Half Moon Bay Lodge
Exterior

Half Moon Bay Lodge

3.0 star property
9.0 out of 10, Wonderful, (1006)
"Beautiful landscaping surrounding area and close to beaches. "
The price is ₩223,087
₩261,477 total
includes taxes & fees
Oct 28 - Oct 29
Half Moon Bay Lodge
Hyatt Centric Fisherman's Wharf San Francisco
Terrace/patio

Hyatt Centric Fisherman's Wharf San Francisco

4.0 star property
8.6 out of 10, Excellent, (1430)
"Great place to stay."
The price is ₩239,651
₩340,138 total
includes taxes & fees
Oct 17 - Oct 18
Hyatt Centric Fisherman's Wharf San Francisco
Hotel Caza Fisherman's Wharf
Exterior

Hotel Caza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (3813)
"very nice place to stay"
The price is ₩239,791
₩346,928 total
includes taxes & fees
Oct 17 - Oct 18
Hotel Caza Fisherman's Wharf
Hotel Riu Plaza Fisherman's Wharf
Lobby sitting area

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (6927)
"It was very close to tourist points, breakfast was superb!"
The price is ₩212,787
₩308,520 total
includes taxes & fees
Oct 17 - Oct 18
Hotel Riu Plaza Fisherman's Wharf
FOUND Hotel Carlton, Nob Hill
Front of property

FOUND Hotel Carlton, Nob Hill

2.0 star property
8.6 out of 10, Excellent, (921)
"Clean rooms and friendly staff."
The price is ₩119,325
₩140,439 total
includes taxes & fees
Oct 19 - Oct 20
FOUND Hotel Carlton, Nob Hill
The Lodge at Tiburon
Front of property

The Lodge at Tiburon

3.5 star property
8.8 out of 10, Excellent, (1018)
"Overall a great stay. "
The price is ₩304,356
₩381,015 total
includes taxes & fees
Oct 5 - Oct 6
The Lodge at Tiburon
Hotel Majestic
Front of property

Hotel Majestic

3.5 star property
9.2 out of 10, Wonderful, (1032)
"Nice, nostalgic hotel. Would definitely stay there again. "
The price is ₩170,518
₩198,668 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Majestic
The Marina Inn on San Francisco Bay
Outdoor pool

The Marina Inn on San Francisco Bay

2.5 star property
8.6 out of 10, Excellent, (2140)
"What a great little gem for the Bay!"
The price is ₩147,624
₩168,291 total
includes taxes & fees
Sep 29 - Sep 30
The Marina Inn on San Francisco Bay
Hotel Nikko San Francisco
Front of property - evening/night

Hotel Nikko San Francisco

4.5 star property
9.4 out of 10, Exceptional, (2593)
"Everything from the staff to the location was excellent. Will definitely stay here again."
The price is ₩259,654
₩370,429 total
includes taxes & fees
Oct 4 - Oct 5
Hotel Nikko San Francisco
Hotel Zephyr San Francisco
Game room

Hotel Zephyr San Francisco

4.0 star property
8.6 out of 10, Excellent, (2240)
"Great location"
The price is ₩202,293
₩287,866 total
includes taxes & fees
Oct 17 - Oct 18
Hotel Zephyr San Francisco
SFO El Rancho Inn SureStay Collection by Best Western
Exterior

SFO El Rancho Inn SureStay Collection by Best Western

3.0 star property
8.4 out of 10, Very Good, (2867)
"Very clean, staff was very helpful and the location is perfect. "
The price is ₩161,750
₩187,137 total
includes taxes & fees
Oct 5 - Oct 6
SFO El Rancho Inn SureStay Collection by Best Western
Hyatt Regency San Francisco Airport
Exterior

Hyatt Regency San Francisco Airport

4.0 star property
8.8 out of 10, Excellent, (1321)
"The location was great"
The price is ₩191,721
₩254,608 total
includes taxes & fees
Oct 26 - Oct 27
Hyatt Regency San Francisco Airport
Hotel Skye SFO
Standard Room, Multiple Beds | In-room safe, desk, laptop workspace, iron/ironing board

Hotel Skye SFO

3.0 star property
8.8 out of 10, Excellent, (1457)
"Great property, friendly staff and close to airport."
The price is ₩150,979
₩181,337 total
includes taxes & fees
Sep 29 - Sep 30
Hotel Skye SFO
The Dylan at SFO
Lobby sitting area

The Dylan at SFO

3.0 star property
9.2 out of 10, Wonderful, (1771)
"Sweet small hotel really close to the SFO Airport with lots of nice amenities for an inexpensive hotel!"
The price is ₩164,344
₩195,273 total
includes taxes & fees
Oct 5 - Oct 6
The Dylan at SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.
Union Square which includes a high rise building and a city

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Fisherman\'s Wharf featuring a bay or harbor

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

Downtown San Francisco featuring railway items

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

South of Market featuring skyline, a city and city views

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill showing a city and street scenes

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Downtown South San Francisco Hotel Reviews

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

10/10 Excellent
"Excellent "
Zoveida 1-night trip
Posted 7 hours ago
Hotel Caza Fisherman's Wharf

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Downtown South San Francisco?

You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood.

What's a favorite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favorite options in the area include Airport Inn and Inn By The SFO.

How many hotels will I find in the Downtown South San Francisco area?

When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodations in Downtown South San Francisco.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco.

Where can I learn more about changing or cancelling my trip to Downtown South San Francisco?

To find more details about picking new dates or cancelling your trip to Downtown South San Francisco, head over to our customer service page.

What can I see and do in this South San Francisco neighborhood?

See's Candies, Cinemark Century at Tanforan, and K1 Speed San Francisco are just a few of the places to visit in and around Downtown South San Francisco. The Shops at Tanforan and San Bruno Point Park are also worth a visit when you're out sightseeing in South San Francisco.