A forested valley with autumn foliage, a rocky cliff, and a sunset.

Southern Illinois, Illinois hotel rooms at the Drury Inn & Suites

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 30 - Aug 31
Tomorrow
Aug 31 - Sep 1
Next weekend
Sep 4 - Sep 6
In two weeks
Sep 11 - Sep 13

Our top choices for Southern Illinois Drury Inn & Suites

A modern lounge area with a sectional sofa, ottomans, and a round table.
A reception desk with a computer, a printer, and a sign that reads "TRAVEL happy". There are chairs and a large window in the background.
A hotel room with two beds, a desk, a chair, a television, and a painting on the wall.
A modern hotel lobby with a seating area, tables, and a large window offering a view of the outdoors.

1. Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights
Fairview Heights
United States
Orbie
₩126,610
₩143,044 total
includes taxes & fees
Sep 6 - Sep 7
Drury Inn & Suites St. Louis Fairview Heights
A bar area with a long counter, multiple chairs, and hanging light fixtures.
A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.
A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.

2. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Kirstyn
₩152,760
₩172,286 total
includes taxes & fees
Sep 6 - Sep 7
Drury Plaza Hotel Mt. Vernon
An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.
A lobby with patterned sofas, a fireplace, and framed pictures on the wall.
A lobby with two armchairs, a lamp, a framed artwork, and a sign indicating a fitness center.
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

3. Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
O'Fallon
United States
KEVIN
₩145,878
₩169,190 total
includes taxes & fees
Sep 6 - Sep 7
Drury Inn & Suites St. Louis O'Fallon, IL
A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.
A restaurant with a brick wall, large windows, and a seating area with tables and chairs.
An indoor swimming pool with clear glass walls, a tiled edge, and a ceiling with metal beams. There are lounge chairs and tables around the pool area.
A spacious indoor area with a large table and chairs, a sofa, and a staircase leading to an upper level.

4. Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
Eastport
United States
James
₩152,760
₩175,643 total
includes taxes & fees
Sep 3 - Sep 4
Drury Inn & Suites St. Louis Collinsville
A spacious lobby with high ceilings, multiple seating areas, and large windows allowing natural light.
An indoor swimming pool with clear water, tiled walls, and a ceiling with square vents.
A spacious lobby with a high ceiling, a central seating area with multiple chairs, a reception desk, and a kitchen area in the background.
An outdoor patio area with a table and chairs, a red umbrella, and a brick building facade.

5. Drury Inn & Suites Marion

Drury Inn & Suites Marion
Marion
United States
Tara
₩132,115
₩158,511 total
includes taxes & fees
Sep 20 - Sep 21
Drury Inn & Suites Marion
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"I will return. Management, Dionna, was awesome."
Grace 1-night trip
Posted 6 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"Great hotel for a last minute stay."
Cynthia 1-night trip
Posted 16 hours ago
Drury Inn & Suites St. Louis Fairview Heights
Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL

10/10 Excellent
"Second time staying at the property. Front desk always friendly. Room was clean."
Muhammad 1-night trip
Posted 18 hours ago
Super 8 by Wyndham Mt. Vernon IL
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

10/10 Excellent
"Staff was very helpful and pleasant. We have stayed here several times and are always happy with our stay. Excellent breakfast."
Patricia 1-night trip
Posted 1 day ago
Holiday Inn Express Metropolis by IHG
Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

8/10 Good
"Room was clean. Could have used a little more lighting but that's just my preference. I had a single king room. The bed was firm but not uncomfortable. Breakfast was a pleasant surprise with eggs and sausage along with waffles, toast, yogurt, cereal, juice and coffee. Fruit would be a nice addition"
Gary 1-night trip
Posted 2 days ago
Ramada by Wyndham Effingham
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

8/10 Good
"Room was clean but highway noise was a bit annoying. Staff was very pleasant and breakfast had a good variety of food."
Merrie 1-night trip
Posted 3 days ago
Baymont by Wyndham Effingham
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

10/10 Excellent
"Free parking, quiet and close to the freeway"
Mihai 1-night trip
Posted 4 days ago
Comfort Inn Edwardsville - St. Louis
Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24

10/10 Excellent
"Tv did not work but everything else was spot on."
Samantha 1-night trip
Posted 5 days ago
Quality Inn & Suites Metropolis I-24

Explore a world of travel with Expedia