Find hotels in Southern Illinois, IL from ₩81,481
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Sep 14 - Sep 15Tomorrow
Sep 15 - Sep 16This weekend
Sep 18 - Sep 20Next weekend
Sep 25 - Sep 27Our top choices for Southern Illinois hotels
1. Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
Kirstyn
₩148,904
₩167,938 total
includes taxes & fees
Sep 27 - Sep 28
2. Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
Tina
₩102,646
₩113,916 total
includes taxes & fees
Sep 21 - Sep 22
3. Best Western Delta Inn
Best Western Delta InnEffingham
Chris
₩115,914
₩129,800 total
includes taxes & fees
Sep 20 - Sep 21
4. Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
Heidi
₩144,879
₩156,444 total
includes taxes & fees
Sep 16 - Sep 17
5. Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
Larry
₩126,969
₩140,908 total
includes taxes & fees
Sep 20 - Sep 21
6. Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
John
₩158,309
₩178,374 total
includes taxes & fees
Sep 27 - Sep 28
7. Comfort Inn & Suites Greenville I-70
Comfort Inn & Suites Greenville I-70Greenville
Debbie
₩131,611
₩146,061 total
includes taxes & fees
Sep 21 - Sep 22
8. Super 8 by Wyndham Mt. Vernon IL
Super 8 by Wyndham Mt. Vernon ILMount Vernon
Matthew W,
₩97,937
₩111,372 total
includes taxes & fees
Sep 16 - Sep 17
9. Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
Kate
₩163,917
₩181,914 total
includes taxes & fees
Sep 27 - Sep 28
10. Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
Sierra
₩107,046
₩118,799 total
includes taxes & fees
Sep 24 - Sep 25
11. Best Western Plus Parkside Inn & Suites
Best Western Plus Parkside Inn & SuitesOlney
Richard
₩169,914
₩188,571 total
includes taxes & fees
Sep 21 - Sep 22
12. Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
Suzanne
₩87,191
₩104,611 total
includes taxes & fees
Sep 27 - Sep 28
13. Best Western Marion Hotel
Best Western Marion HotelMarion
Lauren
₩109,622
₩131,525 total
includes taxes & fees
Sep 20 - Sep 21
14. Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
Penny
₩140,868
₩157,745 total
includes taxes & fees
Sep 24 - Sep 25
15. La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
Alexis
₩152,822
₩171,131 total
includes taxes & fees
Sep 20 - Sep 21
16. Holiday Inn Express Metropolis by IHG
Holiday Inn Express Metropolis by IHGMetropolis
Benjamin
₩130,135
₩144,424 total
includes taxes & fees
Sep 20 - Sep 21
17. Ramada by Wyndham Effingham
Ramada by Wyndham EffinghamEffingham
Kristen
₩90,088
₩100,880 total
includes taxes & fees
Sep 29 - Sep 30
18. Suite Dreams Hotel
Suite Dreams HotelMattoon
Judd
₩127,452
₩142,719 total
includes taxes & fees
Sep 16 - Sep 17
19. Super 8 by Wyndham Troy IL/St. Louis Area
Super 8 by Wyndham Troy IL/St. Louis AreaTroy
Esmeralda
₩91,229
₩101,247 total
includes taxes & fees
Sep 22 - Sep 23
20. Quality Inn & Suites Metropolis I-24
Quality Inn & Suites Metropolis I-24Metropolis
Cierra
₩75,841
₩88,179 total
includes taxes & fees
Sep 27 - Sep 28
Vacation Rentals in Southern Illinois
Cottage
Harrisburg Home w/ Private Yard + Screened Porch!
Harrisburg Home w/ Private Yard + Screened Porch!Harrisburg
"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."
Cottage
Illinois Vacation Rental Home: Pets Welcome
Illinois Vacation Rental Home: Pets WelcomePalestine
Cottage
Cozy Anna Home Near Southern Illinois Attractions!
Cozy Anna Home Near Southern Illinois Attractions!Anna
"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."
Cottage
Country Home Near EIU & Lake Charleston!
Country Home Near EIU & Lake Charleston!Charleston
"Property was very clean and beautifully decorated in a farmhouse style. Very cozy and comfortable! Came stocked with everything you would need. We had fun at nearby Aikman Wildlife Adventure in Arcola, Kayaking in Lake Charleston, hiking in Fox Ridge State Park a visit to Amish country in Arthur, IL. The kitchen, living and dining room were very spacious! The bathroom was very tiny so if staying with 4 adults - be prepared for this. Also there was a strange odor right outside the front entry...
Cottage
Peaceful Robinson Home w/ Yard, Near Golf Courses!
Peaceful Robinson Home w/ Yard, Near Golf Courses!Robinson
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Stay near popular Southern Illinois attractions
Garden of the Gods Recreation Area
9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.
Harrah's Metropolis
8.0/10 (310 reviews)
This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards program to maximize your experience while enjoying Southern classics at the on-site restaurants.
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.
See all hotels in Southern Illinois
Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews
Drury Plaza Hotel Mt. Vernon
10/10 Excellent
"Great job clean room good breakfast"
Drury Inn & Suites St. Louis O'Fallon, IL
10/10 Excellent
"Room was nicely decorated and clean, bed and pillows very comfortable, staff friendly and helpful, breakfast was delicious. Only downside was air conditioning loud with a scratching sound with blower"
Baymont by Wyndham Effingham
8/10 Good
"very quiet"
Holiday Inn Express Metropolis by IHG
10/10 Excellent
"was a great hotel to stop at on a long journey to get some rest"
Motel 6 Caseyville, IL - Caseyville Il
10/10 Excellent
"Clean. Friendly staff good prices"
Quality Inn O'Fallon - St. Louis - Shiloh
8/10 Good
"The room was good but breakfast sucks. Not many choices; just waffles, two kinds of cereal, and toast or bagels. On the plus side there is a Starbucks just pass the entrance/exit of the parking lot."
Ramada by Wyndham Effingham
10/10 Excellent
"Everything was great and great location and great breakfast."
Drury Inn & Suites St. Louis Fairview Heights
10/10 Excellent
"The amenities where excellent and offered more then other places offer. The staff were kind d and friendly. The rooms where clean, comfortable, and up to what you wa t feom a hotel stay.I would stay there again."
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
10/10 Excellent
"I enjoyed my stay at Harrahs. The hotel was nice and clean. The staff was friendly and helpful. I ordered room service food from the grill which arrived quickly and tasted fresh. The only thing I was wondering was why The Bridges didn't have room service. I did go to Bridges for breakfast and it tasted fresh and flavorful. I enjoyed the casino with had a good selection of slots, but I would stay there even without gaming. I enjoyed it very much."
More cheap stays in Southern Illinois
Americas Best Value Inn Collinsville St. Louis
552 Ramada Blvd Collinsville IL
₩70,858
₩81,481 total
Oct 11 - Oct 12
includes taxes & fees
6.4/10 (971 reviews)
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
₩71,843
₩82,605 total
Sep 21 - Sep 22
includes taxes & fees
6.6/10 (1,101 reviews)
Best Western Delta Inn
1509 Hampton Dr Effingham IL
₩115,914
₩129,800 total
Sep 20 - Sep 21
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
Country Inn & Suites by Radisson, Effingham, IL
1200 N Raney Effingham IL
₩126,969
₩140,908 total
Sep 20 - Sep 21
includes taxes & fees
Comfort Inn Edwardsville - St. Louis
3080 S State Route 157 Edwardsville IL
₩123,159
₩141,608 total
Sep 22 - Sep 23
includes taxes & fees
Baymont by Wyndham Marion
2608 W Main St Marion IL
₩126,177
₩151,386 total
Sep 27 - Sep 28
includes taxes & fees
8.4/10 Very Good! (1,095 reviews)
Hotels in Southern Illinois with star-rating
4 Star Hotels
4 properties
3 Star Hotels
84 properties
2 Star Hotels
217 properties
