Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Southwestern Virginia

Spa

Family friendly

Our top choices for Southwestern Virginia hotels

The Highlander at Radford, Tapestry Collection by Hilton

Radford

Julie

₩142,433 total

includes taxes & fees

Jun 2 - Jun 3

Hard Rock Hotel & Casino Bristol

Bristol

Lynne

₩221,114 total

includes taxes & fees

May 26 - May 27

Natural Bridge Hotel, Trademark Collection by Wyndham

Natural Bridge

Elbin Jr.

₩137,576 total

includes taxes & fees

Jun 8 - Jun 9

Tru by Hilton Radford, VA

Christiansburg

Rebecca

₩137,917 total

includes taxes & fees

Jun 2 - Jun 3

Suite, 1 King Bed, Accessible, Non Smoking | Desk, iron/ironing board, rollaway beds, free WiFi

Comfort Inn & Suites Hillsville I-77

Hillsville

Erik

₩165,114 total

includes taxes & fees

Jun 2 - Jun 3

Spark by Hilton Wytheville Holston Rd I 81

Wytheville

Jeanna

₩135,930 total

includes taxes & fees

Jun 16 - Jun 17

Holiday Inn Express Hotel & Suites Christiansburg by IHG

Christiansburg

Thomas

₩143,790 total

includes taxes & fees

Jun 7 - Jun 8

General Francis Marion Hotel

Marion

Liviu

₩164,455 total

includes taxes & fees

May 20 - May 21

Quality Inn Dublin I-81

Dublin

RICHARD

₩112,077 total

includes taxes & fees

May 31 - Jun 1

Hampton Inn Norton, VA

Norton

brandon

₩162,079 total

includes taxes & fees

Jun 14 - Jun 15

Country Inn & Suites by Radisson, Abingdon, VA

Abingdon

John

₩143,446 total

includes taxes & fees

May 25 - May 26

Fairfield Inn by Marriott Christiansburg

Christiansburg

Barbara

₩141,188 total

includes taxes & fees

Jun 2 - Jun 3

Sleep Inn Wytheville I-77 and I-81

Wytheville

Jonathan

₩155,391 total

includes taxes & fees

May 24 - May 25

avid hotel Salem by IHG

Salem

Nancy

₩135,351 total

includes taxes & fees

Jun 7 - Jun 8

Comfort Suites Abingdon I-81

Abingdon

₩147,841 total

includes taxes & fees

May 25 - May 26

Deluxe Room | In-room safe, individually decorated, individually furnished, desk

Hotel Floyd

Floyd

Emily

₩217,407 total

includes taxes & fees

May 26 - May 27

Tru By Hilton Christiansburg

Christiansburg

Dwayne

₩145,558 total

includes taxes & fees

Jun 2 - Jun 3

Jackson Park Inn, an Ascend Collection Hotel

Pulaski

Matthew

₩176,354 total

includes taxes & fees

May 25 - May 26

Americas Best Value Inn & Suites Independence VA

Independence

Laura

₩108,262 total

includes taxes & fees

May 24 - May 25

La Quinta Inn & Suites by Wyndham Roanoke Salem

Salem

Andrea

₩162,945 total

includes taxes & fees

Jun 3 - Jun 4

View all properties

Vacation Rentals in Southwestern Virginia

Apartment

Affordable Corporate Suites Christiansburg

Christiansburg

"Good location, great value, clean"

Aparthotel

The West End Flats

West End

"What a gem, really enjoyed staying at The West End Flats. Our apartment was great, large bathroom, high end kitchen, We didn't need them but full-size washer/dryer was in the unit. AFOG onsite is wonderful, we picked up a brew each night and played corn hole in their back yard. "

Cottage

Cozy Cottage Near Dtwn Dining, Walk to Casino

Bristol

"Quiet neighborhood, close to Hard Rock casino. "

Cabin

4BR Lodge on Wolf Creek – Fishing, Hiking, New River Fun & Hokie Weekends

Narrows

"House was very clean with a well appointed kitchen. Great space for a large family with room to spread out. We love being beside the beautiful creek. "

Cottage

Walk to Roanoke River Greenway: Mountain-view Home

Riverland/Walnut Hill

"Beautiful home in a great location. Just enough room for a family of 4. Comfy house definitely felt like home away from home. Contact person is great and very responsive. "

Apartment

Apt w/ Lake Views - Day Trip to Virginia Tech!

Radford

"This was a great stay! Quiet, peaceful, and beautiful! Host had great hospitality, super kind, and very accommodating! We will definitely stay here again when in the area next! Highly recommended! :)"

Cottage

Cozy Damascus Cottage w/ Porch & Trail Access!

Damascus

Cottage

Cozy Fries Escape w/ Mountain & River Views!

Fries

"The family and I loved this place. Clean, comfortable, has everything well organized, great location, great view of New River. "

Cottage

1 Mi to Dtwn Roanoke: Home w/ Yard & Mtn View!

Riverland/Walnut Hill

"We rented the property for a wedding weekend for 6 people. Essentially used it as a place to shower sleep and wind down. The property has everything you need. Super spacious. Very clean and comfortable. Wonderful backyard to be outside. We did have an issue with the lock. Property owner was very communicative and immediately came to change out the battery. Very apologetic. But it was the responsiveness that was out of this world to correct the situation. I highly recommend renting this...

Apartment

Bristol Escape w/ Patio, 2 Mi to Downtown!

Bristol

"It was so cozy nice weekend getaway "

Cottage

Home w/ Bunkroom: 2 Mi to Hatfield & Mccoy Trail

Bluefield

"Very nice place to stay, like brand new inside."

Cottage

Bristol Retreat w/ Creek Access: 2 Mi to Dtwn

Bristol

"The property was amazing, settled right on a beautiful creek and the property owner was wonderful. "

Cottage

Mountain-view Blue Ridge Cabin Getaway w/ Fire Pit

Callaway

"Wonderful stay for a beautiful VT football weekend. Great place for our family. Gorgeous views and property. "

Cottage

Dog-friendly Home w/ Mtn Views in Chilhowie!

Chilhowie

Apartment

Comfy Damascus Apartment - Walkable Location

Damascus

See all vacation rentals

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southwestern Virginia attractions

Virginia Tech University

4.8/5 (1,791 reviews)

Explore the campus of Virginia Tech University, during your trip to Blacksburg. You can attend a sporting event while in the area.

See properties

Learn more about Southwestern Virginia

Explore the family-friendly area of Southwestern Virginia—a college vibe, sports teams, and sights from Wytheville Meeting Center to Wohlfahrt Haus Dinner Theatre.

See all hotels in Southwestern Virginia

Top Southwestern Virginia Hotel Reviews

Hyatt Place Blacksburg / University

10/10 Excellent

"Great place near virginia tech"

Natural Bridge Hotel, Trademark Collection by Wyndham

4/10 Poor

"Room off to the side of the hotel were very outdated, Cobb webs in the corners and ceilings, floor was old, spongy and broken in a few places that would catch your foot that could possibly be a fall hazard. The rooms in the main hotel may be better, but I have no idea."

Hotel Roanoke & Conference Ctr, Curio Collection by Hilton

10/10 Excellent

"The hotel is a top notch from the moment you park at the front entrance to your departure. The rooms are clean and specious. Everything is modern and in a brand new condition. The front desk, bar and the restaurant are provided excellent service. Valet parking was great too. Highly recommend."

Ramada by Wyndham Wytheville

2/10 Terrible

"SCAM ALERT -- the hotel said that an Expedia glitch forced them to cancel my reservation, even though Expedia had just emailed me to ask "how was your check-in?" They were trying to pull this on the woman in front of me in line too. They said that the only room they could offer me was a smoking room for double the price, even though there were only about 5 cars in the parking lot. My name was on a handwritten list of about a dozen people, and this sure seemed like a bait-and-switch to get customers to book at one price and then blame a "glitch" to charge double the price. Still waiting for my refund."