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Compare 93 hotels in Mississippi County with room rates, reviews, and availability. Most hotels are fully refundable.

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
6.6 out of 10, (603)
"Staff was great! Room was nice. "
United States
Lana
The price is ₩79,721
₩88,470 total
includes taxes & fees
Nov 9 - Nov 10
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston
2.5 star property
6.8 out of 10, (406)
"I consistently choose to stay there due to positive past encounters."
United States
IMTIAZ
The price is ₩94,755
₩105,154 total
includes taxes & fees
Dec 7 - Dec 8
Quality Inn Charleston - Sikeston
Eagle Inn Charleston
2.0 star property
6.8 out of 10, (102)
"Did not look like the picture at all! They charged an extra $50 for amenities that were not used. The room was not clean. There was cockroaches. There were semis next-door that started up at 4:30 in the morning, but at this point, we had no choice because we came in really late and there wasn’t anything else around. Will not stay there again."
United States
Natalie
Eagle Inn Charleston
Quality Inn Cairo I-57
2.5 star property
6.6 out of 10, (271)
"We had a quiet and convenient one night stay. "
United States
Cindy
The price is ₩99,548
₩110,478 total
includes taxes & fees
Nov 16 - Nov 17
Quality Inn Cairo I-57
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi County Hotel Reviews