Lodging Image

Search Hotels in New Madrid County

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Top Cities in New Madrid County

A tree with sunlight filtering through its leaves, creating a warm glow.
HotelsHotels

Sikeston

Sikeston
A cannon on a brick platform by a river, with a steamboat in the background.
HotelsHotels

New Madrid

New Madrid

Check prices for these dates

This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for New Madrid County hotels

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

1. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,001 reviews)
"Awesome place will be staying in more of them"
United States
Tim
The price is ₩126,196
₩145,094 total
includes taxes & fees
Oct 29 - Oct 30
Drury Inn & Suites Sikeston, MO
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

2. Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (638 reviews)
"Great place"
United States
Lori
The price is ₩137,224
₩156,059 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

3. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,000 reviews)
"Clean rooms, great parking, very nice staff"
United States
Shelley
The price is ₩113,843
₩129,753 total
includes taxes & fees
Nov 5 - Nov 6
Best Western Plus Sikeston I-55
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

4. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,001 reviews)
"This was a very good value. It has been the best hotel I've stayed at in awhile."
United States
David
The price is ₩89,018
₩101,459 total
includes taxes & fees
Nov 2 - Nov 3
Days Inn and Suites by Wyndham Sikeston
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

5. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
7.0 out of 10, Good, (687 reviews)
"It is a clean place, and we enjoyed our stay"
United States
Laura
The price is ₩76,692
₩87,410 total
includes taxes & fees
Oct 28 - Oct 29
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

6. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.8 out of 10, Excellent, (517 reviews)
"I have always have a great stay each time I’ve been here. Beds comfortable and rooms very clean."
United States
Melissa
The price is ₩124,969
₩142,122 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Express & Suites Sikeston Southwest by IHG
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

7. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (118 reviews)
"The hotel was very nice and clean. The staff was very friendly and helpful."
United States
Allen
The price is ₩135,608
₩154,219 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites by Marriott Sikeston
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (826 reviews)
"Very clean property and the staff were very accommodating."
United States
Craig
The price is ₩93,301
₩106,340 total
includes taxes & fees
Oct 28 - Oct 29
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A hotel room with two beds, a desk, a chair, a TV, and a mirror.

9. Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (161 reviews)
"Great clean place to stay at"
United States
William
The price is ₩78,451
₩93,338 total
includes taxes & fees
Oct 17 - Oct 18
Country Yard Inn and Suite
A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

10. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (77 reviews)
"Very clean and a very friendly staff! Air conditioner in room wasn’t working perfectly so it felt very humid but overall was not bad. I would stay here again!"
United States
Brenda
The price is ₩74,920
₩85,952 total
includes taxes & fees
Oct 25 - Oct 26
Super 8 By Wyndham Marston
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

11. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (316 reviews)
"Our room was very clean and comfy. The bathroom was clean but could use an update. The bathroom tissue and face tissues are on the thin side. Breafast bar was excellent. The staff was very nice and helpful."
United States
Kathryn
The price is ₩106,553
₩121,445 total
includes taxes & fees
Nov 15 - Nov 16
Comfort Inn & Suites Sikeston I-55
Property amenity

12. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (26 reviews)
"Great location"
United States
Rubin
The price is ₩146,349
₩166,435 total
includes taxes & fees
Oct 22 - Oct 23
TownePlace Suites by Marriott Sikeston
A hotel room with two beds, a television, a desk, and a mirror.

13. Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
5.8 out of 10, (129 reviews)
"Quiet safe area."
United States
Frank
The price is ₩58,741
₩73,265 total
includes taxes & fees
Oct 21 - Oct 22
Travel Inn Marston I-55 by Hotel O
A bedroom with a bed, bedside table, lamp, and a view of the bathroom.

14. OYO Malden Airport Inn

OYO Malden Airport Inn
2.5 star property
Malden
6.4 out of 10, (79 reviews)
"Clean room, cleaning staff friendly, AC working, overflowing dumpster."
United States
James
OYO Malden Airport Inn
A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.

15. Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (513 reviews)
"It’s an older place but very clean"
United States
Danny
The price is ₩81,902
₩93,982 total
includes taxes & fees
Nov 1 - Nov 2
Reelfoot Lake Inn
A cozy cabin-style room with a large L-shaped sectional sofa, a wooden ceiling, and a ladder leading to an upper level.

16. Close to Reelfoot Lake! Dog-friendly Retreat

Close to Reelfoot Lake! Dog-friendly Retreat
2.5 star property
Tiptonville
Close to Reelfoot Lake! Dog-friendly Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top New Madrid County Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent
"We have visited the area many times in the past few years and have had terrible luck at hotels all around the area. This was such a breath of fresh air. The property was beautiful, the room was super clean, the staff was so pleasant and helpful. Breakfast was tasty and the bed was super comfortable. We have found out hotel when we come to town."
Stacy 1-night trip
Posted 5 hours ago
Drury Inn & Suites Hayti Caruthersville