Santo Spirito

Florence

Brancacci Chapel which includes heritage architecture, a church or cathedral and a sunset
Brancacci Chapel which includes heritage architecture and a church or cathedral
Brancacci Chapel featuring heritage elements
Brancacci Chapel which includes a church or cathedral and heritage architecture
Arcetri which includes a city and landscape views

Popular places to visit

Piazza Santo Spirito

Piazza Santo Spirito

Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.

Piazza Santo Spirito
Porta Romana

Porta Romana

Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.

Porta Romana
Brancacci Chapel which includes heritage architecture and a church or cathedral

Brancacci Chapel

A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.

Brancacci Chapel
Uffizi Gallery

Uffizi Gallery

Art lovers will be in their element in this famous museum, home to the most extensive and important collection of masterpieces in the world.

Uffizi Gallery
Ponte Vecchio which includes a bridge and a river or creek

Ponte Vecchio

Take a trip over Florence’s iconic bridge, spared by the Nazis for its beauty and home to jewelers for more than four centuries.

Ponte Vecchio
Cathedral of Santa Maria del Fiore featuring a city, heritage architecture and a church or cathedral

Cathedral of Santa Maria del Fiore

The “Saint Mary of the Flower” cathedral and its towering dome have come to symbolize Florence.

Cathedral of Santa Maria del Fiore

Santo Spirito Hotel Deals

UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59, Florence, FI
Fully refundableReserve now, pay when you stay
The price is ₩135,522 per night from Aug 31 to Sep 1
₩135,522
₩171,698 total
Aug 31 - Sep 1
includes taxes & fees
Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (987 reviews)
"Amazing place, love the decor!"

Reviewed on Jul 28, 2025

UNA Hotels Vittoria Firenze
Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13, Florence, FI
The price is ₩228,911 per night from Aug 20 to Aug 21
₩228,911
₩274,426 total
Aug 20 - Aug 21
includes taxes & fees
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.6/10 Exceptional! (546 reviews)
"Our two night stay at Horto Convento was very nice, from the friendly, helpful staff, to the comfortable bed, to the delicious breakfast. The property is located away from a busy street, in a lovely setting next to a church. If I had to note any issue at all, it would be the very narrow bathroom ..."

Reviewed on Aug 6, 2025

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r, Florence, FI
The price is ₩223,446 per night from Aug 13 to Aug 14
₩223,446
₩268,414 total
Aug 13 - Aug 14
includes taxes & fees
Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,012 reviews)
"Property was very well kept and very comfortable beds. It’s walking distance from most attractions."

Reviewed on Aug 5, 2025

Palazzo Mannaioni Suites
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8, Florence, FI
The price is ₩153,755 per night from Aug 13 to Aug 14
₩153,755
₩188,522 total
Aug 13 - Aug 14
includes taxes & fees
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ...
9/10 Wonderful! (193 reviews)
Perfect spot
"Amazing room, we were on the first floor and had very tall ceilings in a very cool building. Safe area and secure building as well. Highly recommend"

Reviewed on Jul 21, 2025

La Torre Del Cestello
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49, Florence, FI
The price is ₩135,654 per night from Aug 13 to Aug 14
₩135,654
₩168,611 total
Aug 13 - Aug 14
includes taxes & fees
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.8/10 Excellent! (160 reviews)
"Great location, easy to walk to tourist sights and bridges. Room was clean, great air conditioning, comfortable beds and pillows, clean bathroom. Safe, quiet accommodation. Good restaurants nearby. Five stars. Great travel accommodation."

Reviewed on Aug 11, 2025

Foresteria Valdese di Firenze - Casa per Ferie
Casa Santo Nome di Gesù

Casa Santo Nome di Gesù

Piazza del Carmine, 21, Florence, FI
The price is ₩183,827 per night from Aug 14 to Aug 15
₩183,827
₩221,602 total
Aug 14 - Aug 15
includes taxes & fees
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (317 reviews)
"We were there for 2 nights in a room for 5 people; everything was extremely clean and had a good time!"

Reviewed on Aug 9, 2025

Casa Santo Nome di Gesù
See all 468 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santo Spirito

Brancacci Chapel which includes a church or cathedral and heritage architecture

San Frediano

San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica.

San Frediano
Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(529 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4.5/5(1,057 area reviews)

Enjoy the popular shops in Santa Maria Novella. Palazzo dei Congressi is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Uffizi Gallery which includes street scenes as well as a large group of people

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

San Giovanni
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

5/5(2,214 area reviews)

Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Historic Centre of Florence

Santo Spirito