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Compare 158 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Fairfield Inn by Marriott Hartsville

2.5 star property
8.6 out of 10, Excellent, (649)
"Walking distance to restaurants and bar, quiet area, comfortable beds"
The price is ₩129,999
₩145,599 total
includes taxes & fees
Aug 24 - Aug 25
Fairfield Inn by Marriott Hartsville

The Mantissa Hotel

3.0 star property
9.2 out of 10, Wonderful, (251)
"Great location!"
The price is ₩261,248
₩292,596 total
includes taxes & fees
Aug 19 - Aug 20
The Mantissa Hotel

The Landmark Inn

2.5 star property
7.0 out of 10, Good, (297)
"Friendly staff clean quiet room"
The price is ₩111,110
₩129,304 total
includes taxes & fees
Aug 19 - Aug 20
The Landmark Inn

Hampton Inn & Suites Hartsville

2.5 star property
9.2 out of 10, Wonderful, (455)
"Love the area stayed before will stay again "
The price is ₩168,818
₩189,077 total
includes taxes & fees
Aug 24 - Aug 25
Hampton Inn & Suites Hartsville

Quality Inn

2.5 star property
6.0 out of 10, (303)
"Stayed here several times. Inexpensive option for budget travelers. Would like to see the place cleaned up. "
The price is ₩88,069
₩99,625 total
includes taxes & fees
Sep 2 - Sep 3
Quality Inn

Oak Manor Inn

3.0 star property
8.0 out of 10, Very Good, (22)
"The south at it’s very best. Beautiful, comfortable and welcoming. I only wish that we’d had longer to stay. David was very friendly and accommodating. I can’t recommend this beautiful home strongly enough. Stay here……you’ll love it."
The price is ₩151,735
₩169,942 total
includes taxes & fees
Sep 7 - Sep 8
Oak Manor Inn

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
6.8 out of 10, (1005)
"Good quality hotel with affordable pricing."
The price is ₩93,055
₩104,222 total
includes taxes & fees
Aug 19 - Aug 20
Days Inn by Wyndham Florence Near Civic Center

Comfort Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (1051)
"Good service, comfy bed and pillows!"
The price is ₩148,457
₩166,274 total
includes taxes & fees
Sep 14 - Sep 15
Comfort Inn & Suites

Park Inn by Radisson Florence, SC

2.5 star property
9.0 out of 10, Wonderful, (2118)
"Perfect for overnight while traveling, plenty of food options and right off I-95"
The price is ₩116,666
₩130,666 total
includes taxes & fees
Sep 1 - Sep 2
Park Inn by Radisson Florence, SC

Quality Inn & Suites Florence Civic Center

2.5 star property
7.8 out of 10, Good, (1239)
"Great pool, breakfast and rooms. "
The price is ₩124,985
₩139,984 total
includes taxes & fees
Aug 24 - Aug 25
Quality Inn & Suites Florence Civic Center

Howard Johnson by Wyndham Florence

2.0 star property
8.8 out of 10, Excellent, (2341)
"Great hotel, beautiful property, great friendly staff!"
The price is ₩97,652
₩109,371 total
includes taxes & fees
Aug 19 - Aug 20
Howard Johnson by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3.0 star property
8.0 out of 10, Very Good, (1678)
"Nice stay"
The price is ₩148,749
₩166,596 total
includes taxes & fees
Aug 19 - Aug 20
La Quinta Inn & Suites by Wyndham Florence

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
9.4 out of 10, Exceptional, (886)
"Enjoyed the stay "
The price is ₩187,499
₩209,997 total
includes taxes & fees
Aug 24 - Aug 25
Staybridge Suites Florence - Civic Center by IHG

Hampton Inn & Suites Florence-North-I-95

2.5 star property
9.0 out of 10, Wonderful, (730)
"great place to stay"
The price is ₩169,999
₩190,399 total
includes taxes & fees
Aug 24 - Aug 25
Hampton Inn & Suites Florence-North-I-95

Residence Inn Marriott Florence

3.0 star property
8.8 out of 10, Excellent, (413)
"The staff and the breakfast was amazing!!"
The price is ₩148,888
₩166,755 total
includes taxes & fees
Aug 24 - Aug 25
Residence Inn Marriott Florence

Courtyard by Marriott Florence

3.0 star property
7.8 out of 10, Good, (660)
"Great place to stay. Clean and comfortable. Friendly staff and will definitely stay there again."
The price is ₩140,277
₩157,111 total
includes taxes & fees
Aug 24 - Aug 25
Courtyard by Marriott Florence

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

2.5 star property
8.6 out of 10, Excellent, (1001)
"Top notch property and staff."
The price is ₩163,888
₩183,555 total
includes taxes & fees
Aug 21 - Aug 22
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Springhill Suites by Marriott Cheraw

3.0 star property
9.4 out of 10, Exceptional, (243)
"Great place "
The price is ₩181,943
₩203,777 total
includes taxes & fees
Aug 24 - Aug 25
Springhill Suites by Marriott Cheraw

SpringHill Suites by Marriott Florence

3.0 star property
8.6 out of 10, Excellent, (931)
"Great place to stay. "
The price is ₩156,985
₩175,825 total
includes taxes & fees
Aug 24 - Aug 25
SpringHill Suites by Marriott Florence

Hyatt Place Florence Downtown

3.0 star property
8.8 out of 10, Excellent, (1007)
"great visit"
The price is ₩134,721
₩150,887 total
includes taxes & fees
Sep 15 - Sep 16
Hyatt Place Florence Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Hartsville

Stroll along the scenic Black Creek, where kayakers glide past historic buildings and lush parks. Sonoco Park's trails and Kalmia Gardens' blooms offer peaceful retreats, while Coker University's campus adds a vibrant collegiate atmosphere to this charming Southern town.

The boardwalk at Kalmia Gardens
Photo by Jackie Rodriguez
Open Photo by Jackie Rodriguez

Top Hartsville Hotel Reviews

Frequently asked questions

What's the best place to stay in Hartsville?

The Mantissa Hotel is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Hampton Inn & Suites Hartsville and Fairfield Inn by Marriott Hartsville as top options for your trip. See all available top hotels, or vacation rentals in Hartsville.

If I need to cancel my hotel reservation in Hartsville, will I receive a refund?

Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Hartsville.

Where can I learn more about changing or cancelling my trip to Hartsville?

For additional details about updating your trip to Hartsville or cancelling it, click here.

What is the favorite LGBTQ-friendly accommodation in Hartsville?

Fairfield Inn by Marriott Hartsville is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Hampton Inn & Suites Hartsville is another good option for your stay. See all available hotels listed as LGBTQ-friendly in Hartsville.

What's the best pet-friendly place to stay in Hartsville?

Quality Inn is a top hotel for people traveling with their pets, and offers a water park and free WiFi for its human guests. Other good choices for you and your pet include The Landmark Inn and Hampton Inn & Suites Hartsville. See more pet-friendly hotel accommodations in Hartsville.

Where is the best hotel to stay with easy access to Coker College?

Adjacent to Coker College, Fairfield Inn by Marriott Hartsville is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. Other good options close by include Hampton Inn & Suites Hartsville, SC and The Mantissa Hotel.

What about the best place to stay close to Kalmia Gardens?

One of the top choices for your stay is Fairfield Inn by Marriott Hartsville, located 2.7 mi (4.3 km) from Kalmia Gardens, and this hotel offers free breakfast and an outdoor pool. Hampton Inn & Suites Hartsville, SC and The Mantissa Hotel are two other good choices within a few miles.

What are some accommodations with pools in Hartsville?

Hampton Inn & Suites Hartsville is a top hotel with a pool, free buffet breakfast, and free WiFi. View all hotels with pools in Hartsville.

What's the top hotel in Hartsville with an on-site water park or a water park nearby?

Quality Inn is a popular hotel featuring water park access, a seasonal outdoor pool, and free parking. You'll find Neptune Island Waterpark within 3 minutes by car. Check out all hotels with or near waterparks in Hartsville.

What is the best accommodation for staying close to Florence Regional Airport (FLO)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an outdoor pool. It's located 2.2 mi (3.5 km) from Florence Regional Airport. Other good choices near the airport include Hotel Florence, an Ascend Hotel Collection Member and Baymont Inn & Suites Florence by Wyndham.

How is it staying in Hartsville?

Visitors to Hartsville are sure to enjoy the restaurants. Tourists can also enjoy the city's university setting and shopping. In Hartsville, there are 16 hotels and other accommodations to choose from. Find out more about Hartsville.

What should I see while I'm in Hartsville?

Cultural venues include Hartsville Museum and Center Theatre. Landmarks like Kalmia Gardens and East Home Avenue Historic District might be worth a visit. The picturesque setting of Byerly Park and Segars-McKinnon Heritage Preserve exemplify the area's natural beauty. Check out what more to see and do in Expedia's Hartsville guide.

What's the seasonal weather like in Hartsville?

The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 49°F. Average annual precipitation for Hartsville is 52 inches.