
Find hotels in North Central, San Antonio
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Our top choices for North Central hotels

1. La Quinta Inn By Wyndham IH-10 West San Antonio TX
La Quinta Inn By Wyndham IH-10 West San Antonio TX
2. San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3. Holiday Inn Express San Antonio-Airport by IHG
Holiday Inn Express San Antonio-Airport by IHG
4. Drury Plaza Hotel San Antonio Airport
Drury Plaza Hotel San Antonio Airport
5. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
6. Estancia del Norte San Antonio, Tapestry Collection by Hilton
Estancia del Norte San Antonio, Tapestry Collection by Hilton
7. Wyndham Garden San Antonio Airport
Wyndham Garden San Antonio Airport
8. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
9. Comfort Inn and Suites Near Medical Center
Comfort Inn and Suites Near Medical Center
10. Hampton Inn & Suites San Antonio-Airport
Hampton Inn & Suites San Antonio-Airport
11. Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San Antonio
12. Crowne Plaza San Antonio Airport by IHG
Crowne Plaza San Antonio Airport by IHG
13. Omni La Mansion del Rio
Omni La Mansion del Rio
14. Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
15. Hyatt Regency San Antonio Riverwalk
Hyatt Regency San Antonio Riverwalk
16. Hotel Valencia Riverwalk, Valencia Collection
Hotel Valencia Riverwalk, Valencia Collection
17. Drury Plaza Hotel San Antonio Riverwalk
Drury Plaza Hotel San Antonio Riverwalk
18. La Quinta Inn & Suites by Wyndham San Antonio Airport
La Quinta Inn & Suites by Wyndham San Antonio Airport
19. Best Western Plus Downtown North
Best Western Plus Downtown North
20. Hyatt Place San Antonio - Riverwalk
Hyatt Place San Antonio - RiverwalkCompare popular hotels in North Central
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() La Quinta Inn By Wyndham IH-10 West San Antonio TX | 6.2 1,002 reviews | View | ||||||
![]() San Antonio Marriott Northwest Medical Center | 8.6 Excellent 1,193 reviews | View | ||||||
![]() Holiday Inn Express San Antonio-Airport by IHG | 9.4 Exceptional 1,007 reviews | View | ||||||
![]() Drury Inn & Suites San Antonio Northwest Medical Center | 9.2 Wonderful 1,527 reviews | View | ||||||
![]() Courtyard by Marriott Medical Center San Antonio | 8.8 Excellent 1,002 reviews | View |
Where to stay in North Central

Downtown San Antonio
Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Uptown Central
While visiting Uptown Central, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District
While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

Northwest Side
While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.
Top North Central Hotel Reviews

























































































