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Mar 14 - Mar 15
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Mar 15 - Mar 16
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Mar 20 - Mar 22
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Mar 27 - Mar 29

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Our top choices for Santo Spirito hotels

Apartment | Laptop workspace, iron/ironing board, cribs/infant beds, free WiFi

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
9.4 out of 10, Exceptional, (3 reviews)
"Very nice apartment and great location. The included parking and laundry facilities were the reason we selected the property, and were very happy with everything. Overall a lovely stay. "
United States
Michele
The price is ₩102,627
₩287,776 total
includes taxes & fees
Mar 15 - Mar 16
Mamo Florence - Bice & Krizia Apartments
Property entrance

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (197 reviews)
"The room was clean a d comfortable, and the staff was very courteous and helpful. The location was also good with most attractions being a 30 to 40 minute walk or less."
United States
Roger
Foresteria Valdese di Firenze - Casa per Ferie
Double Room, Garden View | Pillowtop beds, minibar, in-room safe, desk

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (174 reviews)
"The room was beautiful and clean, the staff was pleasant, breakfast was fantastic, 10/10"
United States
Dan
The price is ₩166,771
₩203,975 total
includes taxes & fees
Mar 29 - Mar 30
La Fonderia Firenze
Superior Double Room, 1 King Bed | Premium bedding, down comforters, in-room safe, desk

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.0 out of 10, Wonderful, (240 reviews)
"Great location and great rooms"
United States
David
La Torre Del Cestello
Exterior

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
9.0 out of 10, Wonderful, (22 reviews)
"Very goord place to stay"
United States
Victor
The price is ₩90,063
₩119,596 total
includes taxes & fees
Mar 15 - Mar 16
L'Antica Porta Boutique B&B
Lobby sitting area

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (225 reviews)
"Gorgeous room in a beautiful property, very helpful staff, tranquil setting"
United Kingdom
Olivia
The price is ₩427,649
₩494,362 total
includes taxes & fees
Mar 30 - Mar 31
AdAstra Suites
Fireplace

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (169 reviews)
"Great location and extremely charming!"
United States
Brook
The price is ₩298,071
₩351,835 total
includes taxes & fees
Mar 19 - Mar 20
Ottantotto Firenze
Deluxe Quadruple Room | Hypo-allergenic bedding, minibar, in-room safe, free WiFi

Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.6 out of 10, Good, (92 reviews)
"Great service easy check in Clean safe quiet "
United States
Gabriel
The price is ₩103,380
₩134,245 total
includes taxes & fees
Mar 17 - Mar 18
Palazzo Oliveto
Suite | Room amenity

Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is ₩834,770
₩942,195 total
includes taxes & fees
Mar 16 - Mar 17
Torre di Bellosguardo
Royal Double Room | Minibar, in-room safe, soundproofing, free WiFi

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (111 reviews)
"Fabulous place to stay"
United Kingdom
Kenneth
The price is ₩320,013
₩375,962 total
includes taxes & fees
Mar 24 - Mar 25
Oltrarno Splendid
Apartment | Balcony view

Mamo Florence - Maddalena Apartment

Mamo Florence - Maddalena Apartment
Santo Spirito
8.8 out of 10, Excellent, (3 reviews)
"As advertised, the stairs to reach the apartment were quite a work out. The is a nice clothes washing machine but no dryer, so plan for the provided drying rack. Everything was very nice!"
United States
Geoff
Mamo Florence - Maddalena Apartment
Family Apartment | Living area | 40-inch flat-screen TV with digital channels, TV

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.4 out of 10, Very Good, (30 reviews)
"Nice location with easy access to bus stops. Close to good restaurants and bars. "
United States
Prasanna
The price is ₩122,295
₩291,900 total
includes taxes & fees
Mar 16 - Mar 17
Appartamenti degli Artisti by Mmega
Comfort Apartment, 1 Bedroom | 1 bedroom, premium bedding, down comforters, individually decorated

Santo Spirito Bright Flat by Mmega

Santo Spirito Bright Flat by Mmega
Santo Spirito
The price is ₩130,445
₩300,865 total
includes taxes & fees
Mar 15 - Mar 16
Santo Spirito Bright Flat by Mmega
Superior Apartment, Courtyard View | Living area | Flat-screen TV

Borgo San Frediano Hideaway

Borgo San Frediano Hideaway
Santo Spirito
Borgo San Frediano Hideaway
Suite | Egyptian cotton sheets, premium bedding, in-room safe, desk

Palazzo Mannaioni Suites

Palazzo Mannaioni Suites
4.0 star property
Santo Spirito
9.2 out of 10, Wonderful, (1,089 reviews)
"Clean room, great staff, excellent location."
United States
Joseph
Palazzo Mannaioni Suites
Standard Double or Twin Room, 1 Double or 2 Twin Beds, Private Bathroom | Down comforters, individually decorated, individually furnished, desk

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (178 reviews)
"Our stay here was wonderful! The host was so pleasant and the view from the terrace was beautiful. The location was in a great spot for enjoying the Florentine neighborhoods, and close to many of the restaurants recommended to us. We would stay here again in a heartbeat."
United States
Bianca
The price is ₩159,342
₩195,803 total
includes taxes & fees
Mar 15 - Mar 16
1900 Artevita
Panoramic Double Room, 1 Bedroom, Air conditioning, City View | Hypo-allergenic bedding, minibar, blackout drapes, soundproofing

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"My husband and I enjoyed our stay here! Large rooms and bathrooms, wonderful location, and great staff! "
United States
Christina
The price is ₩330,300
₩383,857 total
includes taxes & fees
Mar 22 - Mar 23
SPIRIT OF FLORENCE Boutique Rooms
Front of property

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.6 out of 10, Exceptional, (47 reviews)
"Excellent place to stay!"
United States
Diane
The price is ₩186,423
₩225,593 total
includes taxes & fees
Mar 17 - Mar 18
Palazzo D'Oltrarno - Residenza D'Epoca
Property entrance

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (144 reviews)
"Our stay was wonderful! Roxy was so welcoming and helpful! The room and view was beautiful as well! Great location with amazing food and sights nearby! "
United States
Jacqueline
Residenza D'Epoca Al Numero 8
Lobby

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
Santo Spirito
9.8 out of 10, Exceptional, (626 reviews)
"Lovely location, staff were great"
United Kingdom
Martin
The price is ₩231,926
₩279,067 total
includes taxes & fees
Mar 15 - Mar 16
Hotel Horto Convento
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo featuring heritage architecture and a church or cathedral

Duomo

Piazza di Santa Maria Novella and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Ponte Vecchio showing a bridge and a river or creek

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Basilica of Santa Croce showing a church or cathedral and religious elements

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments

10/10 Excellent
"Claudia was attentive and quickly responsive. The room was in great condition and staff maintained it well. No problems with WiFi and for breakfast, Claudia was flexible in providing. We loved our ‘hidden gem’ close enough for lots of food and shopping options. ❤️🇮🇹❤️ we would stay here again! "
Carmen 6-night trip
Posted 19 hours ago
Drom Florence Rooms & Apartments

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Piazza Santo Spirito and Arno River as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on Expedia customer reviews, Oltrarno Splendid is the highest ranked property in Santo Spirito. This B&B is a short 7-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and free WiFi. Other favorite options in the area include Hotel Horto Convento and La Fonderia Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 496 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
Where can I learn more about changing or cancelling my trip to Santo Spirito?
To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Piazza Santo Spirito and Piazza del Carmine are some other places worth a visit. Piazza di Santa Maria Novella and Cathedral of Santa Maria del Fiore are some favorite places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Santa Maria della Carmine and Brancacci Chapel are also worth a stop.